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Evaluation of a commercial measles virus immunoglobulin M enzyme immunoassay.
J Clin Microbiol. 1991 Dec; 29(12):2865-7.JC

Abstract

Paired serum samples from 93 patients suspected of having measles were assayed for measles virus-specific immunoglobulin M (IgM) antibodies by an enzyme immunoassay (EIA), and the results were compared with results from a complement fixation assay and an EIA for measles virus IgG. By using significant serologic rises as the standard for comparison, the IgM EIA assay had a sensitivity of 85.7%, a specificity of 81.3%, a positive predictive value of 95.7%, and a negative predictive value of 54.2%. This assay can be expected to perform well in outbreak situations.

Authors+Show Affiliations

Biosciences Division, Connecticut State Department of Health Services, Hartford 06144.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1757560

Citation

Mayo, D R., et al. "Evaluation of a Commercial Measles Virus Immunoglobulin M Enzyme Immunoassay." Journal of Clinical Microbiology, vol. 29, no. 12, 1991, pp. 2865-7.
Mayo DR, Brennan T, Cormier DP, et al. Evaluation of a commercial measles virus immunoglobulin M enzyme immunoassay. J Clin Microbiol. 1991;29(12):2865-7.
Mayo, D. R., Brennan, T., Cormier, D. P., Hadler, J., & Lamb, P. (1991). Evaluation of a commercial measles virus immunoglobulin M enzyme immunoassay. Journal of Clinical Microbiology, 29(12), 2865-7.
Mayo DR, et al. Evaluation of a Commercial Measles Virus Immunoglobulin M Enzyme Immunoassay. J Clin Microbiol. 1991;29(12):2865-7. PubMed PMID: 1757560.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of a commercial measles virus immunoglobulin M enzyme immunoassay. AU - Mayo,D R, AU - Brennan,T, AU - Cormier,D P, AU - Hadler,J, AU - Lamb,P, PY - 1991/12/1/pubmed PY - 1991/12/1/medline PY - 1991/12/1/entrez SP - 2865 EP - 7 JF - Journal of clinical microbiology JO - J Clin Microbiol VL - 29 IS - 12 N2 - Paired serum samples from 93 patients suspected of having measles were assayed for measles virus-specific immunoglobulin M (IgM) antibodies by an enzyme immunoassay (EIA), and the results were compared with results from a complement fixation assay and an EIA for measles virus IgG. By using significant serologic rises as the standard for comparison, the IgM EIA assay had a sensitivity of 85.7%, a specificity of 81.3%, a positive predictive value of 95.7%, and a negative predictive value of 54.2%. This assay can be expected to perform well in outbreak situations. SN - 0095-1137 UR - https://www.unboundmedicine.com/medline/citation/1757560/Evaluation_of_a_commercial_measles_virus_immunoglobulin_M_enzyme_immunoassay_ DB - PRIME DP - Unbound Medicine ER -