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[Epidemiological study of the effects of smoking cigarette on thyroid gland].
Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Jan; 28(1):53-6.ZL

Abstract

OBJECTIVE

To investigate the effect of cigarette smoking on thyroid gland volume, thyroid function and thyroid autoantibodies in the areas with different iodine intakes.

METHODS

A cross-sectional epidemiological study in Panshan (mild iodine-deficient area), Zhangwu (more than adequate iodine intake area) and Huanghua (iodine-excessive area) was conducted in 3761 subjects in 1999.80.2 % of them were followed up in 2004. Questionnaires, thyroid function, thyroid autoantibodies, urinary iodine concentration,and thyroid B ultrasound were performed.

RESULTS

The prevalence of goiter was higher in smokers than in non-smokers (15.1% vs. 11.5%, P< 0.05). The average thyroid volume was higher in smokers with phenomenon more obvious in Panshan and Huanghua areas. Data from logistic analysis showed that smoking cigarette was an independent risk factor of goiter. There was no difference in serum TSH and Tg level between smokers and non-smokers. The positive rate of TPOAb (>100 IU/ml) was higher in smokers than in non-smokers(10.8% vs. 9.0 % , P <0.05) and was especially obvious in Huanghua area. Smoking was a independent risk factor of increasing positive rate of TPOAb. During the prospective observation,it was found that the incidence of positive TPOAb(>,100 IU/ml) was 7.4% in the subjects that were from non-smokers turning to smokers and 2.9% in those whose smoking behavior did not change. Logistic analysis indicated that the shifting from non-smoking to smoking was independent risk factor for the increase on high incidence of positive TPOAb.

CONCLUSION

Smoking cigarette was a independent risk factor of goiter. Smoking was also a risk factor of increasing TPOAb positive rate. Shifting from not smoking to smoking was an independent risk factor of increasing high incidence of positive TPOAb.

Authors+Show Affiliations

Department of Endocrinology, 1st Affiliated Hospital, China Medical University, Shenyang 110001, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

17575933

Citation

Gu, Xiao-Lan, et al. "[Epidemiological Study of the Effects of Smoking Cigarette On Thyroid Gland]." Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, vol. 28, no. 1, 2007, pp. 53-6.
Gu XL, Mao JY, Shan ZY, et al. [Epidemiological study of the effects of smoking cigarette on thyroid gland]. Zhonghua Liu Xing Bing Xue Za Zhi. 2007;28(1):53-6.
Gu, X. L., Mao, J. Y., Shan, Z. Y., Teng, X. C., Teng, D., Guan, H. X., Li, Y. S., Yu, X. H., Fan, C. L., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y. Y., Zhao, D., Yang, R., Jiang, Y. Q., Li, C. Y., & Teng, W. P. (2007). [Epidemiological study of the effects of smoking cigarette on thyroid gland]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 28(1), 53-6.
Gu XL, et al. [Epidemiological Study of the Effects of Smoking Cigarette On Thyroid Gland]. Zhonghua Liu Xing Bing Xue Za Zhi. 2007;28(1):53-6. PubMed PMID: 17575933.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Epidemiological study of the effects of smoking cigarette on thyroid gland]. AU - Gu,Xiao-Lan, AU - Mao,Jin-yuan, AU - Shan,Zhong-yan, AU - Teng,Xiao-chun, AU - Teng,Di, AU - Guan,Hai-xia, AU - Li,Yu-shu, AU - Yu,Xiao-hui, AU - Fan,Chen-ling, AU - Chong,Wei, AU - Yang,Fan, AU - Dai,Hong, AU - Yu,Yang, AU - Li,Jia, AU - Chen,Yan-yan, AU - Zhao,Dong, AU - Yang,Rong, AU - Jiang,Ya-qiu, AU - Li,Chen-yang, AU - Teng,Wei-ping, PY - 2007/6/20/pubmed PY - 2010/6/4/medline PY - 2007/6/20/entrez SP - 53 EP - 6 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 28 IS - 1 N2 - OBJECTIVE: To investigate the effect of cigarette smoking on thyroid gland volume, thyroid function and thyroid autoantibodies in the areas with different iodine intakes. METHODS: A cross-sectional epidemiological study in Panshan (mild iodine-deficient area), Zhangwu (more than adequate iodine intake area) and Huanghua (iodine-excessive area) was conducted in 3761 subjects in 1999.80.2 % of them were followed up in 2004. Questionnaires, thyroid function, thyroid autoantibodies, urinary iodine concentration,and thyroid B ultrasound were performed. RESULTS: The prevalence of goiter was higher in smokers than in non-smokers (15.1% vs. 11.5%, P< 0.05). The average thyroid volume was higher in smokers with phenomenon more obvious in Panshan and Huanghua areas. Data from logistic analysis showed that smoking cigarette was an independent risk factor of goiter. There was no difference in serum TSH and Tg level between smokers and non-smokers. The positive rate of TPOAb (>100 IU/ml) was higher in smokers than in non-smokers(10.8% vs. 9.0 % , P <0.05) and was especially obvious in Huanghua area. Smoking was a independent risk factor of increasing positive rate of TPOAb. During the prospective observation,it was found that the incidence of positive TPOAb(>,100 IU/ml) was 7.4% in the subjects that were from non-smokers turning to smokers and 2.9% in those whose smoking behavior did not change. Logistic analysis indicated that the shifting from non-smoking to smoking was independent risk factor for the increase on high incidence of positive TPOAb. CONCLUSION: Smoking cigarette was a independent risk factor of goiter. Smoking was also a risk factor of increasing TPOAb positive rate. Shifting from not smoking to smoking was an independent risk factor of increasing high incidence of positive TPOAb. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/17575933/[Epidemiological_study_of_the_effects_of_smoking_cigarette_on_thyroid_gland]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0254-6450&amp;year=2007&amp;vol=28&amp;issue=1&amp;fpage=53 DB - PRIME DP - Unbound Medicine ER -