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Community identification of natural health product-drug interactions.
Ann Pharmacother. 2007 Jul; 41(7):1124-9.AP

Abstract

BACKGROUND

The majority of Canadians use natural health products (NHPs), most of which are purchased in pharmacies. Community pharmacists regularly field inquiries regarding NHPs. As such, pharmacists are ideally placed to answer questions about NHP use and interactions with other medications.

OBJECTIVE

To identify community pharmacists' familiarity with NHPs and NHP-related adverse events (AEs) and their knowledge and ability to counsel on potential and known NHP-drug interactions.

METHODS

Survey questions were derived from a literature review of previous surveys, data collected from Health Canada, and in consultation with clinicians, pharmacists, policy-makers, and researchers. A convenience sample of 321 community pharmacists in Alberta and British Columbia were asked to participate.

RESULTS

We received responses from 132 pharmacists, resulting in a response rate of 41% (132/321). A total of 19% of the sample had previously reported an adverse event to Health Canada. When asked specifically about NHP-drug interactions/AEs, 47% of pharmacists stated that they had identified a potential interaction; however, only 2 of these reported it to Health Canada. Pharmacists were most familiar (76% of respondents) with the interaction between sertraline and St. John's wort and were least familiar with interactions between NHPs and anti-retrovirals.

CONCLUSIONS

This survey provides evidence to suggest that pharmacists encounter reportable NHP-drug interactions, yet rarely choose to report these events. The current lack of available data on NHP AEs makes it difficult to provide patients and healthcare providers with useful strategies for managing AEs and drug interactions. Changes to the current system of monitoring AEs due to NHPs and further education of healthcare professionals regarding NHP-drug interactions is required.

Authors+Show Affiliations

CARE Program, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17578882

Citation

Charrois, Theresa L., et al. "Community Identification of Natural Health Product-drug Interactions." The Annals of Pharmacotherapy, vol. 41, no. 7, 2007, pp. 1124-9.
Charrois TL, Hill RL, Vu D, et al. Community identification of natural health product-drug interactions. Ann Pharmacother. 2007;41(7):1124-9.
Charrois, T. L., Hill, R. L., Vu, D., Foster, B. C., Boon, H. S., Cramer, K., & Vohra, S. (2007). Community identification of natural health product-drug interactions. The Annals of Pharmacotherapy, 41(7), 1124-9.
Charrois TL, et al. Community Identification of Natural Health Product-drug Interactions. Ann Pharmacother. 2007;41(7):1124-9. PubMed PMID: 17578882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Community identification of natural health product-drug interactions. AU - Charrois,Theresa L, AU - Hill,Richard L, AU - Vu,Duc, AU - Foster,Brian C, AU - Boon,Heather S, AU - Cramer,Kristie, AU - Vohra,Sunita, Y1 - 2007/06/19/ PY - 2007/6/21/pubmed PY - 2007/8/11/medline PY - 2007/6/21/entrez SP - 1124 EP - 9 JF - The Annals of pharmacotherapy JO - Ann Pharmacother VL - 41 IS - 7 N2 - BACKGROUND: The majority of Canadians use natural health products (NHPs), most of which are purchased in pharmacies. Community pharmacists regularly field inquiries regarding NHPs. As such, pharmacists are ideally placed to answer questions about NHP use and interactions with other medications. OBJECTIVE: To identify community pharmacists' familiarity with NHPs and NHP-related adverse events (AEs) and their knowledge and ability to counsel on potential and known NHP-drug interactions. METHODS: Survey questions were derived from a literature review of previous surveys, data collected from Health Canada, and in consultation with clinicians, pharmacists, policy-makers, and researchers. A convenience sample of 321 community pharmacists in Alberta and British Columbia were asked to participate. RESULTS: We received responses from 132 pharmacists, resulting in a response rate of 41% (132/321). A total of 19% of the sample had previously reported an adverse event to Health Canada. When asked specifically about NHP-drug interactions/AEs, 47% of pharmacists stated that they had identified a potential interaction; however, only 2 of these reported it to Health Canada. Pharmacists were most familiar (76% of respondents) with the interaction between sertraline and St. John's wort and were least familiar with interactions between NHPs and anti-retrovirals. CONCLUSIONS: This survey provides evidence to suggest that pharmacists encounter reportable NHP-drug interactions, yet rarely choose to report these events. The current lack of available data on NHP AEs makes it difficult to provide patients and healthcare providers with useful strategies for managing AEs and drug interactions. Changes to the current system of monitoring AEs due to NHPs and further education of healthcare professionals regarding NHP-drug interactions is required. SN - 1542-6270 UR - https://www.unboundmedicine.com/medline/citation/17578882/Community_identification_of_natural_health_product_drug_interactions_ L2 - http://journals.sagepub.com/doi/full/10.1345/aph.1H463?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -