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The use of typhoid vaccines in Asia: the DOMI experience.
Clin Infect Dis. 2007 Jul 15; 45 Suppl 1:S34-8.CI

Abstract

BACKGROUND

Two currently licensed typhoid vaccines have been evaluated in Asia, yet few Asian countries have considered including typhoid vaccines in their vaccination programs. The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction of typhoid vaccines in Asian countries.

METHODS

The centerpiece of the program is a multidisciplinary demonstration project with Vi vaccine in 5 Asian countries. The project includes epidemiologic, economic, sociobehavioral, and policy studies.

RESULTS

Policy makers want evidence on which to base their vaccine-related decisions. The DOMI Program has provided updated information on the typhoid fever burden at several Asian sites. Cost-of-illness studies found high costs to governments and individuals. Sociobehavioral studies indicated a positive attitude toward typhoid vaccines. The results of the demonstration projects indicate that mass-immunization campaigns are feasible and acceptable.

CONCLUSIONS

The DOMI Program has begun to provide momentum for the evidence-based, rational introduction of typhoid vaccines into the public health programs of several Asian countries.

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Authors+Show Affiliations

Ochiai RL
International Vaccine Institute, Kwanak-gu, Seoul, Korea. rlochiai@ivi.int
Acosta CJ
No affiliation info available
Agtini M
No affiliation info available
Bhattacharya SK
No affiliation info available
Bhutta ZA
No affiliation info available
Do CG
No affiliation info available
Dong B
No affiliation info available
Chen X
No affiliation info available
Stanton B
No affiliation info available
Kaljee L
No affiliation info available
Nyamete A
No affiliation info available
Galindo CM
No affiliation info available
von Seidlein L
No affiliation info available
DeRoeck D
No affiliation info available
Jodar L
No affiliation info available
Clemens JD
No affiliation info available

MeSH

Administration, OralAdolescentAdultAsiaChildChild, PreschoolCost of IllnessDeveloping CountriesDrug Administration ScheduleEpidemiologic StudiesEvidence-Based MedicineHealth PolicyHumansImmunization ProgramsMass VaccinationMiddle AgedPolysaccharides, BacterialPoverty AreasProspective StudiesTyphoid FeverTyphoid-Paratyphoid VaccinesVaccines, AttenuatedZea mays

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17582567

Citation

Ochiai, R Leon, et al. "The Use of Typhoid Vaccines in Asia: the DOMI Experience." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 45 Suppl 1, 2007, pp. S34-8.
Ochiai RL, Acosta CJ, Agtini M, et al. The use of typhoid vaccines in Asia: the DOMI experience. Clin Infect Dis. 2007;45 Suppl 1:S34-8.
Ochiai, R. L., Acosta, C. J., Agtini, M., Bhattacharya, S. K., Bhutta, Z. A., Do, C. G., Dong, B., Chen, X., Stanton, B., Kaljee, L., Nyamete, A., Galindo, C. M., von Seidlein, L., DeRoeck, D., Jodar, L., & Clemens, J. D. (2007). The use of typhoid vaccines in Asia: the DOMI experience. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 45 Suppl 1, S34-8.
Ochiai RL, et al. The Use of Typhoid Vaccines in Asia: the DOMI Experience. Clin Infect Dis. 2007 Jul 15;45 Suppl 1:S34-8. PubMed PMID: 17582567.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The use of typhoid vaccines in Asia: the DOMI experience. AU - Ochiai,R Leon, AU - Acosta,Camilo J, AU - Agtini,Magdarina, AU - Bhattacharya,Sujit K, AU - Bhutta,Zulfiqar A, AU - Do,Canh Gia, AU - Dong,Baiqing, AU - Chen,Xinguang, AU - Stanton,Bonita, AU - Kaljee,Linda, AU - Nyamete,Andrew, AU - Galindo,Claudia M, AU - von Seidlein,Lorenz, AU - DeRoeck,Denise, AU - Jodar,Luis, AU - Clemens,John D, PY - 2007/7/14/pubmed PY - 2007/8/19/medline PY - 2007/7/14/entrez SP - S34 EP - 8 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 45 Suppl 1 N2 - BACKGROUND: Two currently licensed typhoid vaccines have been evaluated in Asia, yet few Asian countries have considered including typhoid vaccines in their vaccination programs. The Diseases of the Most Impoverished (DOMI) Program was initiated to provide evidence to decide on the introduction of typhoid vaccines in Asian countries. METHODS: The centerpiece of the program is a multidisciplinary demonstration project with Vi vaccine in 5 Asian countries. The project includes epidemiologic, economic, sociobehavioral, and policy studies. RESULTS: Policy makers want evidence on which to base their vaccine-related decisions. The DOMI Program has provided updated information on the typhoid fever burden at several Asian sites. Cost-of-illness studies found high costs to governments and individuals. Sociobehavioral studies indicated a positive attitude toward typhoid vaccines. The results of the demonstration projects indicate that mass-immunization campaigns are feasible and acceptable. CONCLUSIONS: The DOMI Program has begun to provide momentum for the evidence-based, rational introduction of typhoid vaccines into the public health programs of several Asian countries. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/17582567/The_use_of_typhoid_vaccines_in_Asia:_the_DOMI_experience_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/518144 DB - PRIME DP - Unbound Medicine ER -