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Diagnostic value of color flow mapping and Doppler echocardiography in the quantification of mitral regurgitation in patients with mitral valve prolapse or rheumatic heart disease.
J Am Soc Echocardiogr. 2007 Oct; 20(10):1141-8.JA

Abstract

OBJECTIVES

The objective was to analyze the diagnostic value of the echocardiographic methods used for quantification of mitral regurgitation (MR) in patients with mitral valve prolapse (MVP) or rheumatic heart disease (RHD).

METHODS

The study included 50 patients with MR (mean age of 46.1 years; 35 women), 27 (54%) with RHD and 23 (46%) with MVP. Quantification of the mitral valve regurgitation was obtained by regurgitant orifice area (ROA) and regurgitant volume (RV) by the flow convergence region (FCR) and two-dimensional Doppler echocardiographic methods, regurgitant fraction, jet area (JA), jet area/left atrial area ratio (JA/LAA), and vena contracta (VC). Patients were clinically followed to identify cardiovascular events. Data were analyzed by Pearson, kappa, and receiver operator characteristic curve tests; significance was defined as a P value less than .05.

RESULTS

The correlation between the two methods for ROA and RV were r = 0.79 and r = 0.80, respectively, and between these parameters and regurgitant fraction, VC, JA, and JA/LAA varied from r = 0.54 to r = 0.94 (P lt; .05); the agreement varied from kappa = 0.19 to kappa = 0.83. The highest accuracy to identify patients with clinically significant MR (events at follow-up) was 96% for ROA by FCR, 94% for VC, 86% for RV by FCR, and 86% for JA. No method showed a significant difference between MVP and RHD.

CONCLUSIONS

The methods analyzed had significant correlation and good agreement. ROA by FCR and VC had the best performance to identify severe MR; no significant difference between MVP and RHD was observed.

Authors+Show Affiliations

Disciplina de Cardiologia, Escola Paulista de Medicina-UNIFESP, São Paulo, SP, Brasil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17588714

Citation

Pinheiro, Aurélio Carvalho, et al. "Diagnostic Value of Color Flow Mapping and Doppler Echocardiography in the Quantification of Mitral Regurgitation in Patients With Mitral Valve Prolapse or Rheumatic Heart Disease." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, vol. 20, no. 10, 2007, pp. 1141-8.
Pinheiro AC, Mancuso FJ, Hemerly DF, et al. Diagnostic value of color flow mapping and Doppler echocardiography in the quantification of mitral regurgitation in patients with mitral valve prolapse or rheumatic heart disease. J Am Soc Echocardiogr. 2007;20(10):1141-8.
Pinheiro, A. C., Mancuso, F. J., Hemerly, D. F., Kiyose, A. T., Campos, O., de Andrade, J. L., de Paola, A. A., de Camargo Carvalho, A. C., & Moises, V. A. (2007). Diagnostic value of color flow mapping and Doppler echocardiography in the quantification of mitral regurgitation in patients with mitral valve prolapse or rheumatic heart disease. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, 20(10), 1141-8.
Pinheiro AC, et al. Diagnostic Value of Color Flow Mapping and Doppler Echocardiography in the Quantification of Mitral Regurgitation in Patients With Mitral Valve Prolapse or Rheumatic Heart Disease. J Am Soc Echocardiogr. 2007;20(10):1141-8. PubMed PMID: 17588714.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic value of color flow mapping and Doppler echocardiography in the quantification of mitral regurgitation in patients with mitral valve prolapse or rheumatic heart disease. AU - Pinheiro,Aurélio Carvalho, AU - Mancuso,Frederico José Neves, AU - Hemerly,Daniela Fernanda Alli, AU - Kiyose,Alberto Takeshi, AU - Campos,Orlando, AU - de Andrade,José Lázaro, AU - de Paola,Angelo Amato Vicenzo, AU - de Camargo Carvalho,Antonio Carlos, AU - Moises,Valdir Ambrosio, Y1 - 2007/06/25/ PY - 2006/11/02/received PY - 2007/6/26/pubmed PY - 2007/10/19/medline PY - 2007/6/26/entrez SP - 1141 EP - 8 JF - Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography JO - J Am Soc Echocardiogr VL - 20 IS - 10 N2 - OBJECTIVES: The objective was to analyze the diagnostic value of the echocardiographic methods used for quantification of mitral regurgitation (MR) in patients with mitral valve prolapse (MVP) or rheumatic heart disease (RHD). METHODS: The study included 50 patients with MR (mean age of 46.1 years; 35 women), 27 (54%) with RHD and 23 (46%) with MVP. Quantification of the mitral valve regurgitation was obtained by regurgitant orifice area (ROA) and regurgitant volume (RV) by the flow convergence region (FCR) and two-dimensional Doppler echocardiographic methods, regurgitant fraction, jet area (JA), jet area/left atrial area ratio (JA/LAA), and vena contracta (VC). Patients were clinically followed to identify cardiovascular events. Data were analyzed by Pearson, kappa, and receiver operator characteristic curve tests; significance was defined as a P value less than .05. RESULTS: The correlation between the two methods for ROA and RV were r = 0.79 and r = 0.80, respectively, and between these parameters and regurgitant fraction, VC, JA, and JA/LAA varied from r = 0.54 to r = 0.94 (P lt; .05); the agreement varied from kappa = 0.19 to kappa = 0.83. The highest accuracy to identify patients with clinically significant MR (events at follow-up) was 96% for ROA by FCR, 94% for VC, 86% for RV by FCR, and 86% for JA. No method showed a significant difference between MVP and RHD. CONCLUSIONS: The methods analyzed had significant correlation and good agreement. ROA by FCR and VC had the best performance to identify severe MR; no significant difference between MVP and RHD was observed. SN - 1097-6795 UR - https://www.unboundmedicine.com/medline/citation/17588714/Diagnostic_value_of_color_flow_mapping_and_Doppler_echocardiography_in_the_quantification_of_mitral_regurgitation_in_patients_with_mitral_valve_prolapse_or_rheumatic_heart_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0894-7317(07)00167-8 DB - PRIME DP - Unbound Medicine ER -