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Dissociation of sexual function and sexual bother following autologous sural nerve grafting during radical prostatectomy.
Int J Urol. 2007 Jun; 14(6):510-4.IJ

Abstract

AIM

We prospectively investigated health-related quality of life (HR-QOL), including sexual function and sexual bother, in patients who underwent nerve grafting during a radical prostatectomy in comparison with those who underwent a non-nerve-sparing radical prostatectomy.

METHODS

Between August 2001 and May 2004, radical prostatectomies were performed on 69 patients with clinical T1-T2N0/M0 prostate cancer. Of these, 66 patients (22: nerve-grafting patients, 44: non-nerve-sparing and non-nerve-grafting patients) were enroled into this study. The observation periods ranged from 12-46 months (median: 29 months). The general HR-QOL was measured with the SF-36 General Health Survey and disease-specific HR-QOL was measured with the University of California Los Angeles-Prostate Cancer Index.

RESULTS

Penile tumescence was observed in 11 out of 15 (73.3%) prostate-specific antigen failure-free patients who underwent unilateral nerve grafting with contra-lateral nerve-sparing or bilateral nerve grafting. Vaginal penetration was observed in six out of 15 (40.0%) patients. The time for partial erection and for intercourse, respectively, ranged from 3-21 months (median = 6 months) and 6-36 months (median = 13.5 months). There were no significant differences in general HR-QOL changes over time between the nerve-grafting patients and the patients without any nerve-preserving procedures. The sexual function score was significantly better in the nerve-grafting (bilateral nerve graft or unilateral nerve graft with contra-lateral nerve-sparing) patients than in the non-nerve-sparing/non-nerve-grafting patients. The sexual bother score, however, was more serious for the patients who underwent nerve-grafting surgery than for the non-nerve-sparing/non-nerve-grafting patients.

CONCLUSION

Sexual bother is serious for patients who attempt to maintain sexual function after special surgical procedures, such as nerve-grafting surgery. We should be aware that careful counseling is needed to avoid impatient and excessive hope for the recovery of sexual function.

Authors+Show Affiliations

Department of Urology, Kagawa University, Faculty of Medicine, Kagawa, Japan. uro@med.kagawa-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

17593095

Citation

Kuwata, Yoshihiro, et al. "Dissociation of Sexual Function and Sexual Bother Following Autologous Sural Nerve Grafting During Radical Prostatectomy." International Journal of Urology : Official Journal of the Japanese Urological Association, vol. 14, no. 6, 2007, pp. 510-4.
Kuwata Y, Muneuchi G, Igawa HH, et al. Dissociation of sexual function and sexual bother following autologous sural nerve grafting during radical prostatectomy. Int J Urol. 2007;14(6):510-4.
Kuwata, Y., Muneuchi, G., Igawa, H. H., Tsukuda, F., Inui, M., & Kakehi, Y. (2007). Dissociation of sexual function and sexual bother following autologous sural nerve grafting during radical prostatectomy. International Journal of Urology : Official Journal of the Japanese Urological Association, 14(6), 510-4.
Kuwata Y, et al. Dissociation of Sexual Function and Sexual Bother Following Autologous Sural Nerve Grafting During Radical Prostatectomy. Int J Urol. 2007;14(6):510-4. PubMed PMID: 17593095.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dissociation of sexual function and sexual bother following autologous sural nerve grafting during radical prostatectomy. AU - Kuwata,Yoshihiro, AU - Muneuchi,Gan, AU - Igawa,Hiroharu H, AU - Tsukuda,Fumio, AU - Inui,Masashi, AU - Kakehi,Yoshiyuki, PY - 2007/6/27/pubmed PY - 2007/9/21/medline PY - 2007/6/27/entrez SP - 510 EP - 4 JF - International journal of urology : official journal of the Japanese Urological Association JO - Int J Urol VL - 14 IS - 6 N2 - AIM: We prospectively investigated health-related quality of life (HR-QOL), including sexual function and sexual bother, in patients who underwent nerve grafting during a radical prostatectomy in comparison with those who underwent a non-nerve-sparing radical prostatectomy. METHODS: Between August 2001 and May 2004, radical prostatectomies were performed on 69 patients with clinical T1-T2N0/M0 prostate cancer. Of these, 66 patients (22: nerve-grafting patients, 44: non-nerve-sparing and non-nerve-grafting patients) were enroled into this study. The observation periods ranged from 12-46 months (median: 29 months). The general HR-QOL was measured with the SF-36 General Health Survey and disease-specific HR-QOL was measured with the University of California Los Angeles-Prostate Cancer Index. RESULTS: Penile tumescence was observed in 11 out of 15 (73.3%) prostate-specific antigen failure-free patients who underwent unilateral nerve grafting with contra-lateral nerve-sparing or bilateral nerve grafting. Vaginal penetration was observed in six out of 15 (40.0%) patients. The time for partial erection and for intercourse, respectively, ranged from 3-21 months (median = 6 months) and 6-36 months (median = 13.5 months). There were no significant differences in general HR-QOL changes over time between the nerve-grafting patients and the patients without any nerve-preserving procedures. The sexual function score was significantly better in the nerve-grafting (bilateral nerve graft or unilateral nerve graft with contra-lateral nerve-sparing) patients than in the non-nerve-sparing/non-nerve-grafting patients. The sexual bother score, however, was more serious for the patients who underwent nerve-grafting surgery than for the non-nerve-sparing/non-nerve-grafting patients. CONCLUSION: Sexual bother is serious for patients who attempt to maintain sexual function after special surgical procedures, such as nerve-grafting surgery. We should be aware that careful counseling is needed to avoid impatient and excessive hope for the recovery of sexual function. SN - 0919-8172 UR - https://www.unboundmedicine.com/medline/citation/17593095/Dissociation_of_sexual_function_and_sexual_bother_following_autologous_sural_nerve_grafting_during_radical_prostatectomy_ L2 - https://doi.org/10.1111/j.1442-2042.2006.01695.x DB - PRIME DP - Unbound Medicine ER -