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Pregnancy outcome in women with sickle cell - a five year review.
Niger Postgrad Med J. 2007 Jun; 14(2):151-4.NP

Abstract

OBJECTIVES

To evaluate the cases of sickle cell anaemia in obstetric practice, and to highlight their problems in pregnancy as well as their contribution to maternal and foetal outcome in Nigeria. We believe that the findings would be useful for designing interventions to reduce the obstetric burden of sickle cell disease.

PATIENTS AND MATERIALS

The service delivery record of 42 pregnancies in 39 patients with sickle cell disease was retrospectively reviewed at the University of Benin Teaching Hospital (UBTH) between January 2000 and December 2004.

RESULTS

The incidence of sickle cell disease in the study was 8.7/1000 deliveries. Nearly 62% of the patients were aged 25-34 years, while 76.2% were either nulliparous (Para O) or primiparous (Para 1). There was one grandmultipara (2.38%). Anaemia (95.25%), Malaria (33.33%), Bone pain crisis (23.81%), and pneumonia (19.05%) in that order of frequency were the most common complications of pregnancy. The perinatal mortality rate was 250 per 1000 births while the maternal mortality rate was 47.6 per 1000 pregnancies. At delivery, 20% of cases had caesarean section (5% elective and 15% emergency) and the instrumental interventions include 12.5% vacuum and 27.5% forceps respectively.

CONCLUSION

Early booking, good antenatal care and supervised hospital delivery produced a better obstetric outcome.

Authors+Show Affiliations

Department of Obstetrics and Gynaecology, College of Health Sciences, Delta State University, Abraka.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17599116

Citation

Omo-Aghoja, I O., and F E. Okonofua. "Pregnancy Outcome in Women With Sickle Cell - a Five Year Review." The Nigerian Postgraduate Medical Journal, vol. 14, no. 2, 2007, pp. 151-4.
Omo-Aghoja IO, Okonofua FE. Pregnancy outcome in women with sickle cell - a five year review. Niger Postgrad Med J. 2007;14(2):151-4.
Omo-Aghoja, I. O., & Okonofua, F. E. (2007). Pregnancy outcome in women with sickle cell - a five year review. The Nigerian Postgraduate Medical Journal, 14(2), 151-4.
Omo-Aghoja IO, Okonofua FE. Pregnancy Outcome in Women With Sickle Cell - a Five Year Review. Niger Postgrad Med J. 2007;14(2):151-4. PubMed PMID: 17599116.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pregnancy outcome in women with sickle cell - a five year review. AU - Omo-Aghoja,I O, AU - Okonofua,F E, PY - 2007/6/30/pubmed PY - 2007/8/19/medline PY - 2007/6/30/entrez SP - 151 EP - 4 JF - The Nigerian postgraduate medical journal JO - Niger Postgrad Med J VL - 14 IS - 2 N2 - OBJECTIVES: To evaluate the cases of sickle cell anaemia in obstetric practice, and to highlight their problems in pregnancy as well as their contribution to maternal and foetal outcome in Nigeria. We believe that the findings would be useful for designing interventions to reduce the obstetric burden of sickle cell disease. PATIENTS AND MATERIALS: The service delivery record of 42 pregnancies in 39 patients with sickle cell disease was retrospectively reviewed at the University of Benin Teaching Hospital (UBTH) between January 2000 and December 2004. RESULTS: The incidence of sickle cell disease in the study was 8.7/1000 deliveries. Nearly 62% of the patients were aged 25-34 years, while 76.2% were either nulliparous (Para O) or primiparous (Para 1). There was one grandmultipara (2.38%). Anaemia (95.25%), Malaria (33.33%), Bone pain crisis (23.81%), and pneumonia (19.05%) in that order of frequency were the most common complications of pregnancy. The perinatal mortality rate was 250 per 1000 births while the maternal mortality rate was 47.6 per 1000 pregnancies. At delivery, 20% of cases had caesarean section (5% elective and 15% emergency) and the instrumental interventions include 12.5% vacuum and 27.5% forceps respectively. CONCLUSION: Early booking, good antenatal care and supervised hospital delivery produced a better obstetric outcome. SN - 1117-1936 UR - https://www.unboundmedicine.com/medline/citation/17599116/Pregnancy_outcome_in_women_with_sickle_cell___a_five_year_review_ DB - PRIME DP - Unbound Medicine ER -