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Extraintestinal pathogenic Escherichia coli.
Foodborne Pathog Dis. 2007 Summer; 4(2):134-63.FP

Abstract

Extraintestinal pathogenic Escherichia coli (ExPEC) possesses virulence traits that allow it to invade, colonize, and induce disease in bodily sites outside of the gastrointestinal tract. Human diseases caused by ExPEC include urinary tract infections, neonatal meningitis, sepsis, pneumonia, surgical site infections, as well as infections in other extraintestinal locations. ExPEC-induced diseases represent a large burden in terms of medical costs and productivity losses. In addition to human illnesses, ExPEC strains also cause extraintestinal infections in domestic animals and pets. A commonality of virulence factors has been demonstrated between human and animal ExPEC, suggesting that the organisms are zoonotic pathogens. ExPEC strains have been isolated from food products, in particular from raw meats and poultry, indicating that these organisms potentially represent a new class of foodborne pathogens. This review discusses various aspects of ExPEC, including its presence in food products, in animals used for food or as companion pets; the diseases ExPEC can cause; and the virulence factors and virulence mechanisms that cause disease.

Authors+Show Affiliations

United States Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, Wyndmoor, Pennsylvania 19038, USA. james.smith@ars.usda.govNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17600482

Citation

Smith, James L., et al. "Extraintestinal Pathogenic Escherichia Coli." Foodborne Pathogens and Disease, vol. 4, no. 2, 2007, pp. 134-63.
Smith JL, Fratamico PM, Gunther NW. Extraintestinal pathogenic Escherichia coli. Foodborne Pathog Dis. 2007;4(2):134-63.
Smith, J. L., Fratamico, P. M., & Gunther, N. W. (2007). Extraintestinal pathogenic Escherichia coli. Foodborne Pathogens and Disease, 4(2), 134-63.
Smith JL, Fratamico PM, Gunther NW. Extraintestinal Pathogenic Escherichia Coli. Foodborne Pathog Dis. 2007;4(2):134-63. PubMed PMID: 17600482.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extraintestinal pathogenic Escherichia coli. AU - Smith,James L, AU - Fratamico,Pina M, AU - Gunther,Nereus W, PY - 2007/6/30/pubmed PY - 2007/9/5/medline PY - 2007/6/30/entrez SP - 134 EP - 63 JF - Foodborne pathogens and disease JO - Foodborne Pathog Dis VL - 4 IS - 2 N2 - Extraintestinal pathogenic Escherichia coli (ExPEC) possesses virulence traits that allow it to invade, colonize, and induce disease in bodily sites outside of the gastrointestinal tract. Human diseases caused by ExPEC include urinary tract infections, neonatal meningitis, sepsis, pneumonia, surgical site infections, as well as infections in other extraintestinal locations. ExPEC-induced diseases represent a large burden in terms of medical costs and productivity losses. In addition to human illnesses, ExPEC strains also cause extraintestinal infections in domestic animals and pets. A commonality of virulence factors has been demonstrated between human and animal ExPEC, suggesting that the organisms are zoonotic pathogens. ExPEC strains have been isolated from food products, in particular from raw meats and poultry, indicating that these organisms potentially represent a new class of foodborne pathogens. This review discusses various aspects of ExPEC, including its presence in food products, in animals used for food or as companion pets; the diseases ExPEC can cause; and the virulence factors and virulence mechanisms that cause disease. SN - 1535-3141 UR - https://www.unboundmedicine.com/medline/citation/17600482/Extraintestinal_pathogenic_Escherichia_coli_ L2 - https://www.liebertpub.com/doi/10.1089/fpd.2007.0087?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -