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Chronic venous disorders: correlation between visible signs, symptoms, and presence of functional disease.

Abstract

BACKGROUND

The aim of this study was to investigate the frequency of chronic venous disorders (CVD) in different demographic groups in Italy and to provide correlations between patterns of valve incompetence and clinical feature of disease severity.

METHODS

Advertisements in television and newspapers in 53 Italian cities were used to solicit 16,251 subjects (13,826 women, mean age 50.4 years; 2,425 men, mean age 59.1 years). They underwent a clinical examination of the lower limbs, including presence and severity of visible signs (CEAP classification), and assessment of functional disease by color-coded duplex ultrasound imaging.

RESULTS

Varicose veins and telangiectases were the most common objective signs in both men and women. Older people were more severely affected. Telangiectases were more frequent in women, and men had a higher incidence of trunk varices, trophic changes, and venous reflux. Frequency of both visible and functional venous disease increased with family history and body mass index. Presence of reflux correlated positively with increasing CEAP grade of visible disease (Pfor trend < .0001 for all superficial venous segments). A large number of subjects, especially women, complained of subjective symptoms in the legs, and the presence of symptoms correlated almost always positively with both worsening of visible findings (P for trend < .001) and presence of hemodynamic change in both genders.

CONCLUSIONS

The frequency of reflux increased with the severity of visible signs of disease as described by the CEAP classification. In men, the occurrence of subjective symptoms was mostly correlated with functional disorders.

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  • Authors+Show Affiliations

    ,

    Vita-Salute University, Scientific Institute H. San Raffaele, Milan, Italy.

    , , ,

    Source

    Journal of vascular surgery 46:2 2007 Aug pg 322-30

    MeSH

    Adult
    Chronic Disease
    Cross-Sectional Studies
    Female
    Health Surveys
    Humans
    Incidence
    Italy
    Lower Extremity
    Male
    Middle Aged
    Risk Factors
    Severity of Illness Index
    Telangiectasis
    Ultrasonography, Doppler, Color
    Varicose Veins
    Venous Insufficiency

    Pub Type(s)

    Journal Article
    Multicenter Study

    Language

    eng

    PubMed ID

    17600668

    Citation

    Chiesa, Roberto, et al. "Chronic Venous Disorders: Correlation Between Visible Signs, Symptoms, and Presence of Functional Disease." Journal of Vascular Surgery, vol. 46, no. 2, 2007, pp. 322-30.
    Chiesa R, Marone EM, Limoni C, et al. Chronic venous disorders: correlation between visible signs, symptoms, and presence of functional disease. J Vasc Surg. 2007;46(2):322-30.
    Chiesa, R., Marone, E. M., Limoni, C., Volontè, M., & Petrini, O. (2007). Chronic venous disorders: correlation between visible signs, symptoms, and presence of functional disease. Journal of Vascular Surgery, 46(2), pp. 322-30.
    Chiesa R, et al. Chronic Venous Disorders: Correlation Between Visible Signs, Symptoms, and Presence of Functional Disease. J Vasc Surg. 2007;46(2):322-30. PubMed PMID: 17600668.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Chronic venous disorders: correlation between visible signs, symptoms, and presence of functional disease. AU - Chiesa,Roberto, AU - Marone,Enrico Maria, AU - Limoni,Costanzo, AU - Volontè,Marina, AU - Petrini,Orlando, Y1 - 2007/06/27/ PY - 2007/02/12/received PY - 2007/04/07/accepted PY - 2007/6/30/pubmed PY - 2007/8/25/medline PY - 2007/6/30/entrez SP - 322 EP - 30 JF - Journal of vascular surgery JO - J. Vasc. Surg. VL - 46 IS - 2 N2 - BACKGROUND: The aim of this study was to investigate the frequency of chronic venous disorders (CVD) in different demographic groups in Italy and to provide correlations between patterns of valve incompetence and clinical feature of disease severity. METHODS: Advertisements in television and newspapers in 53 Italian cities were used to solicit 16,251 subjects (13,826 women, mean age 50.4 years; 2,425 men, mean age 59.1 years). They underwent a clinical examination of the lower limbs, including presence and severity of visible signs (CEAP classification), and assessment of functional disease by color-coded duplex ultrasound imaging. RESULTS: Varicose veins and telangiectases were the most common objective signs in both men and women. Older people were more severely affected. Telangiectases were more frequent in women, and men had a higher incidence of trunk varices, trophic changes, and venous reflux. Frequency of both visible and functional venous disease increased with family history and body mass index. Presence of reflux correlated positively with increasing CEAP grade of visible disease (Pfor trend < .0001 for all superficial venous segments). A large number of subjects, especially women, complained of subjective symptoms in the legs, and the presence of symptoms correlated almost always positively with both worsening of visible findings (P for trend < .001) and presence of hemodynamic change in both genders. CONCLUSIONS: The frequency of reflux increased with the severity of visible signs of disease as described by the CEAP classification. In men, the occurrence of subjective symptoms was mostly correlated with functional disorders. SN - 0741-5214 UR - https://www.unboundmedicine.com/medline/citation/17600668/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S0741-5214(07)00633-7 DB - PRIME DP - Unbound Medicine ER -