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Depression and coronary heart disease: a review of the epidemiological evidence, explanatory mechanisms and management approaches.

Abstract

There is compelling evidence that depression is an independent risk factor for both the development of Coronary Heart Disease (CHD) and for worsening prognosis once CHD is established. Given the increasing awareness of the high prevalence of co-morbid depression in individuals with CHD, clinical psychologists are likely to become increasingly involved in the care of cardiac patients. It is imperative therefore, that they are aware of the complex relationship between depression and CHD and are familiar with the pharmacological and psychological interventions most likely to be effective in these patients. The following review explores the epidemiological evidence for the relationship between depression and CHD, examines the biological, behavioral and social mechanisms that may account for this relationship, and considers the findings of the psychological and pharmacological intervention trials seeking to improve outcomes for depressed cardiac patients. Collaboration across a range of disciplines is needed to establish a program of research and professional education and to develop clinical practice guidelines and pathways which support the implementation of best practice in the assessment and management of co-morbid depression in people with and at risk of CHD. Clinical psychologists are well-equipped to take a lead in this important endeavor.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    National Heart Foundation of Australia (NSW Division), Australia. kerrie.goldston@heartfoundation.com.au

    Source

    Clinical psychology review 28:2 2008 Feb pg 288-306

    MeSH

    Antidepressive Agents
    Causality
    Cognitive Behavioral Therapy
    Coronary Disease
    Depressive Disorder
    Evidence-Based Medicine
    Humans
    Practice Guidelines as Topic
    Prognosis
    Risk Factors
    Treatment Outcome

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't
    Review

    Language

    eng

    PubMed ID

    17601644

    Citation

    Goldston, Kerrie, and Andrew J. Baillie. "Depression and Coronary Heart Disease: a Review of the Epidemiological Evidence, Explanatory Mechanisms and Management Approaches." Clinical Psychology Review, vol. 28, no. 2, 2008, pp. 288-306.
    Goldston K, Baillie AJ. Depression and coronary heart disease: a review of the epidemiological evidence, explanatory mechanisms and management approaches. Clin Psychol Rev. 2008;28(2):288-306.
    Goldston, K., & Baillie, A. J. (2008). Depression and coronary heart disease: a review of the epidemiological evidence, explanatory mechanisms and management approaches. Clinical Psychology Review, 28(2), pp. 288-306.
    Goldston K, Baillie AJ. Depression and Coronary Heart Disease: a Review of the Epidemiological Evidence, Explanatory Mechanisms and Management Approaches. Clin Psychol Rev. 2008;28(2):288-306. PubMed PMID: 17601644.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Depression and coronary heart disease: a review of the epidemiological evidence, explanatory mechanisms and management approaches. AU - Goldston,Kerrie, AU - Baillie,Andrew J, Y1 - 2007/05/25/ PY - 2006/02/09/received PY - 2007/04/30/revised PY - 2007/05/18/accepted PY - 2007/7/3/pubmed PY - 2008/6/6/medline PY - 2007/7/3/entrez SP - 288 EP - 306 JF - Clinical psychology review JO - Clin Psychol Rev VL - 28 IS - 2 N2 - There is compelling evidence that depression is an independent risk factor for both the development of Coronary Heart Disease (CHD) and for worsening prognosis once CHD is established. Given the increasing awareness of the high prevalence of co-morbid depression in individuals with CHD, clinical psychologists are likely to become increasingly involved in the care of cardiac patients. It is imperative therefore, that they are aware of the complex relationship between depression and CHD and are familiar with the pharmacological and psychological interventions most likely to be effective in these patients. The following review explores the epidemiological evidence for the relationship between depression and CHD, examines the biological, behavioral and social mechanisms that may account for this relationship, and considers the findings of the psychological and pharmacological intervention trials seeking to improve outcomes for depressed cardiac patients. Collaboration across a range of disciplines is needed to establish a program of research and professional education and to develop clinical practice guidelines and pathways which support the implementation of best practice in the assessment and management of co-morbid depression in people with and at risk of CHD. Clinical psychologists are well-equipped to take a lead in this important endeavor. SN - 0272-7358 UR - https://www.unboundmedicine.com/medline/citation/17601644/Depression_and_coronary_heart_disease:_a_review_of_the_epidemiological_evidence_explanatory_mechanisms_and_management_approaches_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0272-7358(07)00105-5 DB - PRIME DP - Unbound Medicine ER -