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[Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly].
Clin Calcium 2007; 17(7):1098-104CC

Abstract

The incidence of osteoporotic fractures increases along aging and the importance of their prevention is more emphasized in the elderly. Although the major determinants for fragile fractures in the elderly are not only the lower bone strength but also frailty and fall, treatments with anti-resorbers are effective also in the elderly. On the other hands, nutritional agents such as active vitamin D3 and vitamin K2 are effective in reducing the fracture incidences in spite of their modest effects on bone mineral density. Recently, the effects of vitamin Ds on the reduction of fall events are noticed and the prevention of osteoporotic fractures in the elderly through extra-skeletal mechanisms seems promising.

Authors+Show Affiliations

National Center for Geriatrics and Gerontology, Department of Advanced Medicine.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

17607078

Citation

Hosoi, Takayuki, and World Health Organization. "[Absolute Risk for Fracture and WHO Guideline. Pharmacological Intervention to Prevent Osteoporotic Fractures in the Elderly]." Clinical Calcium, vol. 17, no. 7, 2007, pp. 1098-104.
Hosoi T, World Health Organization. [Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly]. Clin Calcium. 2007;17(7):1098-104.
Hosoi, T. (2007). [Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly]. Clinical Calcium, 17(7), pp. 1098-104.
Hosoi T, World Health Organization. [Absolute Risk for Fracture and WHO Guideline. Pharmacological Intervention to Prevent Osteoporotic Fractures in the Elderly]. Clin Calcium. 2007;17(7):1098-104. PubMed PMID: 17607078.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Absolute risk for fracture and WHO guideline. Pharmacological intervention to prevent osteoporotic fractures in the elderly]. AU - Hosoi,Takayuki, AU - ,, PY - 2007/7/4/pubmed PY - 2007/8/29/medline PY - 2007/7/4/entrez SP - 1098 EP - 104 JF - Clinical calcium JO - Clin Calcium VL - 17 IS - 7 N2 - The incidence of osteoporotic fractures increases along aging and the importance of their prevention is more emphasized in the elderly. Although the major determinants for fragile fractures in the elderly are not only the lower bone strength but also frailty and fall, treatments with anti-resorbers are effective also in the elderly. On the other hands, nutritional agents such as active vitamin D3 and vitamin K2 are effective in reducing the fracture incidences in spite of their modest effects on bone mineral density. Recently, the effects of vitamin Ds on the reduction of fall events are noticed and the prevention of osteoporotic fractures in the elderly through extra-skeletal mechanisms seems promising. SN - 0917-5857 UR - https://www.unboundmedicine.com/medline/citation/17607078/[Absolute_risk_for_fracture_and_WHO_guideline__Pharmacological_intervention_to_prevent_osteoporotic_fractures_in_the_elderly]_ L2 - https://medlineplus.gov/osteoporosis.html DB - PRIME DP - Unbound Medicine ER -