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[Identification of jizhi syrup using HPLC fingerprint].
Zhongguo Zhong Yao Za Zhi. 2007 Apr; 32(8):681-3.ZZ

Abstract

OBJECTIVE

To establish a HPLC fingerprint for quantitative analysis of the active constituents of jizhi syrup.

METHOD

HPLC analysis was performed on a Zorbax Sb C18 column (4.6 mm x 250 mm, 5 microm), the mobile phase in gradient elution was composed of (A) 1% acetic acid solution (including 0.2% triethylamine) and (B) acetonitrile, at a flow rate of 1.0 mL x min(-1). The column temperature was 30 degrees C and the wavelength was 280 nm.

RESULT

21 common peaks were tested in 10 batches of samples. Compared with the standard fingerprint, the similarity of each sample was greater than 0.99. At the same time, protocatechuic acid, protocatechu aldehyde, chlorogenic acid, caffeic acid, naringin and neohesperidin were found in all samples.

CONCLUSION

The established method can be used for the quality control of jizhi syrup.

Authors+Show Affiliations

Qu QL
Instistute of Chinese Materia Medical, China Academy of Traditional Chinese Medicine, Beijing 100700, China.
Yang B
No affiliation info available
Wang QP
No affiliation info available
Yi CQ
No affiliation info available
Xiao YQ
No affiliation info available
Wang YY
No affiliation info available

MeSH

Antitussive AgentsBenzaldehydesCatecholsChlorogenic AcidChromatography, High Pressure LiquidDrug CombinationsDrugs, Chinese HerbalFlavanonesHydroxybenzoatesPlants, MedicinalReproducibility of Results

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

17608218

Citation

Qu, Qiao-ling, et al. "[Identification of Jizhi Syrup Using HPLC Fingerprint]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 32, no. 8, 2007, pp. 681-3.
Qu QL, Yang B, Wang QP, et al. [Identification of jizhi syrup using HPLC fingerprint]. Zhongguo Zhong Yao Za Zhi. 2007;32(8):681-3.
Qu, Q. L., Yang, B., Wang, Q. P., Yi, C. Q., Xiao, Y. Q., & Wang, Y. Y. (2007). [Identification of jizhi syrup using HPLC fingerprint]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 32(8), 681-3.
Qu QL, et al. [Identification of Jizhi Syrup Using HPLC Fingerprint]. Zhongguo Zhong Yao Za Zhi. 2007;32(8):681-3. PubMed PMID: 17608218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Identification of jizhi syrup using HPLC fingerprint]. AU - Qu,Qiao-ling, AU - Yang,Bin, AU - Wang,Qian-peng, AU - Yi,Chong-qin, AU - Xiao,Yong-qing, AU - Wang,Yong-yan, PY - 2007/7/5/pubmed PY - 2008/5/20/medline PY - 2007/7/5/entrez SP - 681 EP - 3 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 32 IS - 8 N2 - OBJECTIVE: To establish a HPLC fingerprint for quantitative analysis of the active constituents of jizhi syrup. METHOD: HPLC analysis was performed on a Zorbax Sb C18 column (4.6 mm x 250 mm, 5 microm), the mobile phase in gradient elution was composed of (A) 1% acetic acid solution (including 0.2% triethylamine) and (B) acetonitrile, at a flow rate of 1.0 mL x min(-1). The column temperature was 30 degrees C and the wavelength was 280 nm. RESULT: 21 common peaks were tested in 10 batches of samples. Compared with the standard fingerprint, the similarity of each sample was greater than 0.99. At the same time, protocatechuic acid, protocatechu aldehyde, chlorogenic acid, caffeic acid, naringin and neohesperidin were found in all samples. CONCLUSION: The established method can be used for the quality control of jizhi syrup. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/17608218/[Identification_of_jizhi_syrup_using_HPLC_fingerprint]_ L2 - https://medlineplus.gov/coldandcoughmedicines.html DB - PRIME DP - Unbound Medicine ER -