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A new flavonoid glycoside from the leaf of Cephalotaxus koreana.
Fitoterapia. 2007 Sep; 78(6):409-13.F

Abstract

A new flavone glycoside, apigenin 5-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside (1), along with four known flavonol glycosides (2-5), were isolated from the leaf of Cephalotaxus koreana. The new glycoside 1 showed inhibitory activity in superoxide radical scavenging assay with IC(50) value of 13.0 microM, while it showed weak activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. Compounds 2-5 exhibited antioxidant activity in scavenging DPPH and superoxide radicals with IC(50) values ranging from 5.7 to 22.3 microM.

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Authors+Show Affiliations

Bae K
College of Pharmacy, Chungnam National University, Daejeon, South Korea. baekh@cnu.ac.kr
Jin W
No affiliation info available
Thuong PT
No affiliation info available
Min BS
No affiliation info available
Na M
No affiliation info available
Lee YM
No affiliation info available
Kang SS
No affiliation info available

MeSH

Biphenyl CompoundsCephalotaxusFlavonesFree Radical ScavengersGlycosidesHumansInhibitory Concentration 50PhytotherapyPicratesPlant ExtractsPlant LeavesSuperoxides

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17616262

Citation

Bae, Kihwan, et al. "A New Flavonoid Glycoside From the Leaf of Cephalotaxus Koreana." Fitoterapia, vol. 78, no. 6, 2007, pp. 409-13.
Bae K, Jin W, Thuong PT, et al. A new flavonoid glycoside from the leaf of Cephalotaxus koreana. Fitoterapia. 2007;78(6):409-13.
Bae, K., Jin, W., Thuong, P. T., Min, B. S., Na, M., Lee, Y. M., & Kang, S. S. (2007). A new flavonoid glycoside from the leaf of Cephalotaxus koreana. Fitoterapia, 78(6), 409-13.
Bae K, et al. A New Flavonoid Glycoside From the Leaf of Cephalotaxus Koreana. Fitoterapia. 2007;78(6):409-13. PubMed PMID: 17616262.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new flavonoid glycoside from the leaf of Cephalotaxus koreana. AU - Bae,Kihwan, AU - Jin,Wenyi, AU - Thuong,Phuong Thien, AU - Min,Byung Sun, AU - Na,Minkyun, AU - Lee,Young Mi, AU - Kang,Sam Sik, Y1 - 2007/04/11/ PY - 2006/01/11/received PY - 2007/02/23/accepted PY - 2007/7/10/pubmed PY - 2007/11/6/medline PY - 2007/7/10/entrez SP - 409 EP - 13 JF - Fitoterapia JO - Fitoterapia VL - 78 IS - 6 N2 - A new flavone glycoside, apigenin 5-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside (1), along with four known flavonol glycosides (2-5), were isolated from the leaf of Cephalotaxus koreana. The new glycoside 1 showed inhibitory activity in superoxide radical scavenging assay with IC(50) value of 13.0 microM, while it showed weak activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. Compounds 2-5 exhibited antioxidant activity in scavenging DPPH and superoxide radicals with IC(50) values ranging from 5.7 to 22.3 microM. SN - 0367-326X UR - https://www.unboundmedicine.com/medline/citation/17616262/A_new_flavonoid_glycoside_from_the_leaf_of_Cephalotaxus_koreana_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(07)00083-4 DB - PRIME DP - Unbound Medicine ER -