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Chlorine sensitivity of feline calicivirus, a norovirus surrogate.
Appl Environ Microbiol. 2007 Sep; 73(17):5679-82.AE

Abstract

The sensitivity to free chlorine of feline calicivirus (FCV), a norovirus surrogate, was examined relative to chlorine demand. When a crude suspension of FCV was treated with a sodium hypochlorite solution containing 10 microg/ml free chlorine, the extent of the decrease of viral infectivity clearly depended on the volume of the reaction mixture. The apparent sensitivity of FCV to free chlorine increased with the reduction of host cell debris, indicating that chlorine demand must be minimized to know the true sensitivity of the virus. We therefore partially purified the viruses from the host cell components and found that the infectivity of FCV was reduced by more than log 4.6 by 5 min of treatment with 300 ng/ml free chlorine.

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Authors+Show Affiliations

Urakami H
College of Applied Life Sciences, Niigata University of Pharmacy and Applied Life Sciences (NUPALS), 265-1 Higashijima, Niigata, Niigata 956-8603, Japan. urakami@nupals.ac.jp
Ikarashi K
No affiliation info available
Okamoto K
No affiliation info available
Abe Y
No affiliation info available
Ikarashi T
No affiliation info available
Kono T
No affiliation info available
Konagaya Y
No affiliation info available
Tanaka N
No affiliation info available

MeSH

AnimalsCalicivirus, FelineCatsCell LineChlorineDisinfectantsDisinfectionHumansMicrobial Sensitivity TestsNorovirusSodium Hypochlorite

Pub Type(s)

Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17616623

Citation

Urakami, Hiroshi, et al. "Chlorine Sensitivity of Feline Calicivirus, a Norovirus Surrogate." Applied and Environmental Microbiology, vol. 73, no. 17, 2007, pp. 5679-82.
Urakami H, Ikarashi K, Okamoto K, et al. Chlorine sensitivity of feline calicivirus, a norovirus surrogate. Appl Environ Microbiol. 2007;73(17):5679-82.
Urakami, H., Ikarashi, K., Okamoto, K., Abe, Y., Ikarashi, T., Kono, T., Konagaya, Y., & Tanaka, N. (2007). Chlorine sensitivity of feline calicivirus, a norovirus surrogate. Applied and Environmental Microbiology, 73(17), 5679-82.
Urakami H, et al. Chlorine Sensitivity of Feline Calicivirus, a Norovirus Surrogate. Appl Environ Microbiol. 2007;73(17):5679-82. PubMed PMID: 17616623.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chlorine sensitivity of feline calicivirus, a norovirus surrogate. AU - Urakami,Hiroshi, AU - Ikarashi,Kumiko, AU - Okamoto,Ko, AU - Abe,Yukari, AU - Ikarashi,Tamami, AU - Kono,Takeshi, AU - Konagaya,Yukifumi, AU - Tanaka,Nobumasa, Y1 - 2007/07/06/ PY - 2007/7/10/pubmed PY - 2007/10/24/medline PY - 2007/7/10/entrez SP - 5679 EP - 82 JF - Applied and environmental microbiology JO - Appl Environ Microbiol VL - 73 IS - 17 N2 - The sensitivity to free chlorine of feline calicivirus (FCV), a norovirus surrogate, was examined relative to chlorine demand. When a crude suspension of FCV was treated with a sodium hypochlorite solution containing 10 microg/ml free chlorine, the extent of the decrease of viral infectivity clearly depended on the volume of the reaction mixture. The apparent sensitivity of FCV to free chlorine increased with the reduction of host cell debris, indicating that chlorine demand must be minimized to know the true sensitivity of the virus. We therefore partially purified the viruses from the host cell components and found that the infectivity of FCV was reduced by more than log 4.6 by 5 min of treatment with 300 ng/ml free chlorine. SN - 0099-2240 UR - https://www.unboundmedicine.com/medline/citation/17616623/Chlorine_sensitivity_of_feline_calicivirus_a_norovirus_surrogate_ L2 - http://aem.asm.org/cgi/pmidlookup?view=long&pmid=17616623 DB - PRIME DP - Unbound Medicine ER -