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Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART.
AIDS. 2007 Jul 31; 21(12):1641-3.AIDS

Abstract

In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression.

Authors+Show Affiliations

Department of Clinical Sciences, Malmo University Hospital, Lund University, Malmo, Sweden.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17630561

Citation

Björkman, Per, et al. "Enhanced and Resumed GB Virus C Replication in HIV-1-infected Individuals Receiving HAART." AIDS (London, England), vol. 21, no. 12, 2007, pp. 1641-3.
Björkman P, Flamholc L, Molnegren V, et al. Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART. AIDS. 2007;21(12):1641-3.
Björkman, P., Flamholc, L., Molnegren, V., Marshall, A., Güner, N., & Widell, A. (2007). Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART. AIDS (London, England), 21(12), 1641-3.
Björkman P, et al. Enhanced and Resumed GB Virus C Replication in HIV-1-infected Individuals Receiving HAART. AIDS. 2007 Jul 31;21(12):1641-3. PubMed PMID: 17630561.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enhanced and resumed GB virus C replication in HIV-1-infected individuals receiving HAART. AU - Björkman,Per, AU - Flamholc,Leo, AU - Molnegren,Vilma, AU - Marshall,Aline, AU - Güner,Nuray, AU - Widell,Anders, PY - 2007/7/17/pubmed PY - 2007/9/29/medline PY - 2007/7/17/entrez SP - 1641 EP - 3 JF - AIDS (London, England) JO - AIDS VL - 21 IS - 12 N2 - In patients co-infected with HIV-1 and GB virus C (GBV-C), the disappearance of GBV-C RNA has been associated with accelerated disease progression. We studied longitudinal GBV-C viral titres in 28 HIV-1/GVB-C co-infected individuals receiving HAART. During HAART, median GBV-C RNA titres increased from 95 to 6000 copies/ml (P < 0.001). In patients interrupting HAART, GBV-C-RNA titres decreased as HIV replication resumed. These findings further support the theory that GBV-C replication could depend on the dynamics of HIV progression. SN - 0269-9370 UR - https://www.unboundmedicine.com/medline/citation/17630561/Enhanced_and_resumed_GB_virus_C_replication_in_HIV_1_infected_individuals_receiving_HAART_ L2 - https://doi.org/10.1097/QAD.0b013e32823bc9b7 DB - PRIME DP - Unbound Medicine ER -