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WITHDRAWN: Maternal antigen avoidance during lactation for preventing atopic eczema in infants.
Cochrane Database Syst Rev 2007; (4):CD000131CD

Abstract

BACKGROUND

Background pending.

OBJECTIVES

To assess the effects of prescribing an antigen avoidance diet to lactating mothers of infants with atopic eczema on the severity of the eczema.

SEARCH STRATEGY

The register of clinical trials maintained and updated by the Cochrane Pregnancy and Childbirth Group. Date of last search: October 2001.

SELECTION CRITERIA

All acceptably controlled comparisons of maternal antigen avoidance prescribed to lactating mothers of infants with atopic eczema, regardless of the degree of antigen avoidance (number of foods eliminated from the diet) or its duration.

DATA COLLECTION AND ANALYSIS

Data were extracted by the author from published reports, and supplemented by additional information from trialists contacted by the author.

MAIN RESULTS

One trial involving 17 women was included. Based on this single small trial, maternal antigen avoidance was associated with a nonsignificant reduction in eczema severity.

AUTHORS' CONCLUSIONS

The unimpressive results of this single trial should be interpreted with caution both because of its small size (n=17) and because the trial compared exposure to cow milk and egg with exposure to soya milk (soya can itself be allergenic). Maternal reports of changes in the severity of their breast-fed infants' eczema following ingestion of certain foods should be pursued by performing multiple (preferably double-blinded) challenges and dechallenges with the suspected foods.

Authors+Show Affiliations

McGill University, Faculty of Medicine, 1020 Pine Avenue West, Montreal, Quebec, Canada, H3A 1A2. michael.kramer@mcgill.ca

Pub Type(s)

Journal Article
Review
Systematic Review

Language

eng

PubMed ID

17636598

Citation

Kramer, M S.. "WITHDRAWN: Maternal Antigen Avoidance During Lactation for Preventing Atopic Eczema in Infants." The Cochrane Database of Systematic Reviews, 2007, p. CD000131.
Kramer MS. WITHDRAWN: Maternal antigen avoidance during lactation for preventing atopic eczema in infants. Cochrane Database Syst Rev. 2007.
Kramer, M. S. (2007). WITHDRAWN: Maternal antigen avoidance during lactation for preventing atopic eczema in infants. The Cochrane Database of Systematic Reviews, (4), p. CD000131.
Kramer MS. WITHDRAWN: Maternal Antigen Avoidance During Lactation for Preventing Atopic Eczema in Infants. Cochrane Database Syst Rev. 2007 Jul 18;(4)CD000131. PubMed PMID: 17636598.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - WITHDRAWN: Maternal antigen avoidance during lactation for preventing atopic eczema in infants. A1 - Kramer,M S, Y1 - 2007/07/18/ PY - 2007/7/20/pubmed PY - 2007/10/19/medline PY - 2007/7/20/entrez SP - CD000131 EP - CD000131 JF - The Cochrane database of systematic reviews JO - Cochrane Database Syst Rev IS - 4 N2 - BACKGROUND: Background pending. OBJECTIVES: To assess the effects of prescribing an antigen avoidance diet to lactating mothers of infants with atopic eczema on the severity of the eczema. SEARCH STRATEGY: The register of clinical trials maintained and updated by the Cochrane Pregnancy and Childbirth Group. Date of last search: October 2001. SELECTION CRITERIA: All acceptably controlled comparisons of maternal antigen avoidance prescribed to lactating mothers of infants with atopic eczema, regardless of the degree of antigen avoidance (number of foods eliminated from the diet) or its duration. DATA COLLECTION AND ANALYSIS: Data were extracted by the author from published reports, and supplemented by additional information from trialists contacted by the author. MAIN RESULTS: One trial involving 17 women was included. Based on this single small trial, maternal antigen avoidance was associated with a nonsignificant reduction in eczema severity. AUTHORS' CONCLUSIONS: The unimpressive results of this single trial should be interpreted with caution both because of its small size (n=17) and because the trial compared exposure to cow milk and egg with exposure to soya milk (soya can itself be allergenic). Maternal reports of changes in the severity of their breast-fed infants' eczema following ingestion of certain foods should be pursued by performing multiple (preferably double-blinded) challenges and dechallenges with the suspected foods. SN - 1469-493X UR - https://www.unboundmedicine.com/medline/citation/17636598/WITHDRAWN:_Maternal_antigen_avoidance_during_lactation_for_preventing_atopic_eczema_in_infants_ L2 - https://doi.org/10.1002/14651858.CD000131 DB - PRIME DP - Unbound Medicine ER -