Tags

Type your tag names separated by a space and hit enter

Low glycaemic index or low glycaemic load diets for overweight and obesity.
Cochrane Database Syst Rev 2007; (3):CD005105CD

Abstract

BACKGROUND

Obesity is increasingly prevalent, yet the nutritional management remains contentious. It has been suggested that low glycaemic index or load diets may stimulate greater weight loss than higher glycaemic index or load diets or other weight reduction diets.

OBJECTIVES

To assess the effects of low glycaemic index or load diets for weight loss in overweight or obese people.

SEARCH STRATEGY

Trials were identified through The Cochrane Library, MEDLINE, EMBASE, CINAHL and manual searches of bibliographies.

SELECTION CRITERIA

Randomised controlled trials comparing a low glycaemic index or load diet (LGI) with a higher glycaemic index or load diet or other diet (Cdiet) in overweight or obese people.

DATA COLLECTION AND ANALYSIS

Two authors independently selected trials, assessed quality and extracted data, including any information provided on adverse effects.

MAIN RESULTS

We identified six eligible randomised controlled trials (total of 202 participants). Interventions ranged from five weeks to six months duration with up to six months follow-up after the intervention ceased. The decrease in body mass (WMD -1.1 kg, 95% confidence interval (CI) -2.0 to -0.2, P < 0.05) (n = 163), total fat mass (WMD -1.1 kg, 95% CI -1.9 to -0.4, P < 0.05) (n =147) and body mass index (WMD -1.3, 95% CI -2.0 to -0.5, P < 0.05) (n = 48) was significantly greater in participants receiving LGI compared to Cdiets. The decrease in total cholesterol was significantly greater with LGI compared to Cdiets (WMD -0.22 mmol/L, 95% CI -0.43 to -0.02, P < 0.05), as was the change in LDL-cholesterol (WMD -0.24 mmol/L, 95% CI -0.44 to -0.05, P < 0.05). No study reported adverse effects, mortality or quality of life data.

AUTHORS' CONCLUSIONS

Overweight or obese people on LGI lost more weight and had more improvement in lipid profiles than those receiving Cdiets. Body mass, total fat mass, body mass index, total cholesterol and LDL-cholesterol all decreased significantly more in the LGI group. In studies comparing ad libitum LGI diets to conventional restricted energy low-fat diets, participants fared as well or better on th LGI diet, even though they could eat as much as desired. Lowering the glycaemic load of the diet appears to be an effective method of promoting weight loss and improving lipid profiles and can be simply incorporated into a person's lifestyle. Further research with longer term follow-up will determine whether improvement continues long-term and improves quality of life.

Authors+Show Affiliations

University of Sydney, Children's Hospital at Westmead, CEBPGAN (Centre for Evidence Based Paediatrics Gastroenterology and Nutrition), Locked Bag 4001, Westmead, Australia, NSW 2145. dianat@chw.edu.au

Pub Type(s)

Journal Article
Meta-Analysis
Review
Systematic Review

Language

eng

PubMed ID

17636786

Citation

Thomas, D E., et al. "Low Glycaemic Index or Low Glycaemic Load Diets for Overweight and Obesity." The Cochrane Database of Systematic Reviews, 2007, p. CD005105.
Thomas DE, Elliott EJ, Baur L. Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst Rev. 2007.
Thomas, D. E., Elliott, E. J., & Baur, L. (2007). Low glycaemic index or low glycaemic load diets for overweight and obesity. The Cochrane Database of Systematic Reviews, (3), p. CD005105.
Thomas DE, Elliott EJ, Baur L. Low Glycaemic Index or Low Glycaemic Load Diets for Overweight and Obesity. Cochrane Database Syst Rev. 2007 Jul 18;(3)CD005105. PubMed PMID: 17636786.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Low glycaemic index or low glycaemic load diets for overweight and obesity. AU - Thomas,D E, AU - Elliott,E J, AU - Baur,L, Y1 - 2007/07/18/ PY - 2007/7/20/pubmed PY - 2007/10/19/medline PY - 2007/7/20/entrez SP - CD005105 EP - CD005105 JF - The Cochrane database of systematic reviews JO - Cochrane Database Syst Rev IS - 3 N2 - BACKGROUND: Obesity is increasingly prevalent, yet the nutritional management remains contentious. It has been suggested that low glycaemic index or load diets may stimulate greater weight loss than higher glycaemic index or load diets or other weight reduction diets. OBJECTIVES: To assess the effects of low glycaemic index or load diets for weight loss in overweight or obese people. SEARCH STRATEGY: Trials were identified through The Cochrane Library, MEDLINE, EMBASE, CINAHL and manual searches of bibliographies. SELECTION CRITERIA: Randomised controlled trials comparing a low glycaemic index or load diet (LGI) with a higher glycaemic index or load diet or other diet (Cdiet) in overweight or obese people. DATA COLLECTION AND ANALYSIS: Two authors independently selected trials, assessed quality and extracted data, including any information provided on adverse effects. MAIN RESULTS: We identified six eligible randomised controlled trials (total of 202 participants). Interventions ranged from five weeks to six months duration with up to six months follow-up after the intervention ceased. The decrease in body mass (WMD -1.1 kg, 95% confidence interval (CI) -2.0 to -0.2, P < 0.05) (n = 163), total fat mass (WMD -1.1 kg, 95% CI -1.9 to -0.4, P < 0.05) (n =147) and body mass index (WMD -1.3, 95% CI -2.0 to -0.5, P < 0.05) (n = 48) was significantly greater in participants receiving LGI compared to Cdiets. The decrease in total cholesterol was significantly greater with LGI compared to Cdiets (WMD -0.22 mmol/L, 95% CI -0.43 to -0.02, P < 0.05), as was the change in LDL-cholesterol (WMD -0.24 mmol/L, 95% CI -0.44 to -0.05, P < 0.05). No study reported adverse effects, mortality or quality of life data. AUTHORS' CONCLUSIONS: Overweight or obese people on LGI lost more weight and had more improvement in lipid profiles than those receiving Cdiets. Body mass, total fat mass, body mass index, total cholesterol and LDL-cholesterol all decreased significantly more in the LGI group. In studies comparing ad libitum LGI diets to conventional restricted energy low-fat diets, participants fared as well or better on th LGI diet, even though they could eat as much as desired. Lowering the glycaemic load of the diet appears to be an effective method of promoting weight loss and improving lipid profiles and can be simply incorporated into a person's lifestyle. Further research with longer term follow-up will determine whether improvement continues long-term and improves quality of life. SN - 1469-493X UR - https://www.unboundmedicine.com/medline/citation/17636786/Low_glycaemic_index_or_low_glycaemic_load_diets_for_overweight_and_obesity_ L2 - https://doi.org/10.1002/14651858.CD005105.pub2 DB - PRIME DP - Unbound Medicine ER -