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Drugs in oral fluid in randomly selected drivers.
Forensic Sci Int. 2007 Aug 06; 170(2-3):105-10.FS

Abstract

There were 13,176 roadside drug tests performed in the first year of the random drug-testing program conducted in the state of Victoria. Drugs targeted in the testing were methamphetamines and Delta(9)-tetrahydrocannabinol (THC). On-site screening was conducted by the police using DrugWipe, while the driver was still in the vehicle and if positive, a second test on collected oral fluid, using the Rapiscan, was performed in a specially outfitted "drug bus" located adjacent to the testing area. Oral fluid on presumptive positive cases was sent to the laboratory for confirmation with limits of quantification of 5, 5, and 2 ng/mL for methamphetamine (MA), methylenedioxy-methamphetamine (MDMA), and THC, respectively. Recovery experiments conducted in the laboratory showed quantitative recovery of analytes from the collector. When oral fluid could not be collected, blood was taken from the driver and sent to the laboratory for confirmation. These roadside tests gave 313 positive cases following GC-MS confirmation. These comprised 269, 118, and 87 cases positive to MA, MDMA, and THC, respectively. The median oral concentrations (undiluted) of MA, MDMA, and THC was 1136, 2724, and 81 ng/mL. The overall drug positive rate was 2.4% of the screened population. This rate was highest in drivers of cars (2.8%). The average age of drivers detected with a positive drug reading was 28 years. Large vehicle (trucks over 4.5 t) drivers were older; on average at 38 years. Females accounted for 19% of all positives, although none of the positive truck drivers were female. There was one false positive to cannabis when the results of both on-site devices were considered and four to methamphetamines.

Authors+Show Affiliations

Victorian Institute of Forensic Medicine, Department of Forensic Medicine, Monash University, Southbank, Australia. olaf@vifm.org <olaf@vifm.org>No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17658711

Citation

Drummer, Olaf H., et al. "Drugs in Oral Fluid in Randomly Selected Drivers." Forensic Science International, vol. 170, no. 2-3, 2007, pp. 105-10.
Drummer OH, Gerostamoulos D, Chu M, et al. Drugs in oral fluid in randomly selected drivers. Forensic Sci Int. 2007;170(2-3):105-10.
Drummer, O. H., Gerostamoulos, D., Chu, M., Swann, P., Boorman, M., & Cairns, I. (2007). Drugs in oral fluid in randomly selected drivers. Forensic Science International, 170(2-3), 105-10.
Drummer OH, et al. Drugs in Oral Fluid in Randomly Selected Drivers. Forensic Sci Int. 2007 Aug 6;170(2-3):105-10. PubMed PMID: 17658711.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drugs in oral fluid in randomly selected drivers. AU - Drummer,Olaf H, AU - Gerostamoulos,Dimitri, AU - Chu,Mark, AU - Swann,Philip, AU - Boorman,Martin, AU - Cairns,Ian, Y1 - 2007/07/20/ PY - 2006/10/09/received PY - 2007/03/01/revised PY - 2007/03/03/accepted PY - 2007/7/31/pubmed PY - 2007/10/19/medline PY - 2007/7/31/entrez SP - 105 EP - 10 JF - Forensic science international JO - Forensic Sci Int VL - 170 IS - 2-3 N2 - There were 13,176 roadside drug tests performed in the first year of the random drug-testing program conducted in the state of Victoria. Drugs targeted in the testing were methamphetamines and Delta(9)-tetrahydrocannabinol (THC). On-site screening was conducted by the police using DrugWipe, while the driver was still in the vehicle and if positive, a second test on collected oral fluid, using the Rapiscan, was performed in a specially outfitted "drug bus" located adjacent to the testing area. Oral fluid on presumptive positive cases was sent to the laboratory for confirmation with limits of quantification of 5, 5, and 2 ng/mL for methamphetamine (MA), methylenedioxy-methamphetamine (MDMA), and THC, respectively. Recovery experiments conducted in the laboratory showed quantitative recovery of analytes from the collector. When oral fluid could not be collected, blood was taken from the driver and sent to the laboratory for confirmation. These roadside tests gave 313 positive cases following GC-MS confirmation. These comprised 269, 118, and 87 cases positive to MA, MDMA, and THC, respectively. The median oral concentrations (undiluted) of MA, MDMA, and THC was 1136, 2724, and 81 ng/mL. The overall drug positive rate was 2.4% of the screened population. This rate was highest in drivers of cars (2.8%). The average age of drivers detected with a positive drug reading was 28 years. Large vehicle (trucks over 4.5 t) drivers were older; on average at 38 years. Females accounted for 19% of all positives, although none of the positive truck drivers were female. There was one false positive to cannabis when the results of both on-site devices were considered and four to methamphetamines. SN - 1872-6283 UR - https://www.unboundmedicine.com/medline/citation/17658711/Drugs_in_oral_fluid_in_randomly_selected_drivers_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0379-0738(07)00558-0 DB - PRIME DP - Unbound Medicine ER -