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Ultrasound-guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer?
J Clin Ultrasound. 2007 Sep; 35(7):363-6.JC

Abstract

PURPOSE

To investigate the number of cores required to diagnose breast cancer using ultrasound (US)-guided core needle biopsy.

METHODS

US-guided core biopsy of 150 masses was performed in 144 patients. For each mass, 6 cores were obtained and analyzed separately. The histopathologic diagnosis was classified as benign, malignant, or normal breast tissue. Each core was analyzed separately. For diagnostic purposes, the cases were grouped as follows: group G1 comprised the first core; group G2 comprised the first and second core; group G3 comprised the first 3 cores; up to group G6, which included all 6 cores. The results were also analyzed by tumor size (</=2 cm and >2 cm).

RESULTS

The sensitivity in the diagnosis of breast cancer was 90.1% in group G1 and 94.1% in the remaining groups (G2-G6). In tumors </=2 cm, the sensitivity was 88.4% for group G1 and 90.7% for the others, whereas for tumors >2 cm the sensitivity was 91.4% for group G1 and 96.6% when 2 or more cores were obtained.

CONCLUSION

It appears that 2 cores are sufficient to diagnose breast cancer in this study population assuming no technical error occurred in US guidance of the needle through the mass.

Authors+Show Affiliations

Santa Casa de Belo Horizonte, Universidade Federal de Minas Gerais, Avenida Bernardo Monteiro, no. 1470, Apto. 1202, Bairro Funcionários, Belo Horizonte, Minas Gerais, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

17663457

Citation

de Lucena, Clécio Enio Murta, et al. "Ultrasound-guided Core Needle Biopsy of Breast Masses: How Many Cores Are Necessary to Diagnose Cancer?" Journal of Clinical Ultrasound : JCU, vol. 35, no. 7, 2007, pp. 363-6.
de Lucena CE, Dos Santos Júnior JL, de Lima Resende CA, et al. Ultrasound-guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer? J Clin Ultrasound. 2007;35(7):363-6.
de Lucena, C. E., Dos Santos Júnior, J. L., de Lima Resende, C. A., do Amaral, V. F., de Almeida Barra, A., & Reis, J. H. (2007). Ultrasound-guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer? Journal of Clinical Ultrasound : JCU, 35(7), 363-6.
de Lucena CE, et al. Ultrasound-guided Core Needle Biopsy of Breast Masses: How Many Cores Are Necessary to Diagnose Cancer. J Clin Ultrasound. 2007;35(7):363-6. PubMed PMID: 17663457.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ultrasound-guided core needle biopsy of breast masses: How many cores are necessary to diagnose cancer? AU - de Lucena,Clécio Enio Murta, AU - Dos Santos Júnior,João Lúcio, AU - de Lima Resende,César Alencar, AU - do Amaral,Vănia Fonseca, AU - de Almeida Barra,Alexandre, AU - Reis,Joño Henrique Pena, PY - 2007/8/1/pubmed PY - 2007/12/15/medline PY - 2007/8/1/entrez SP - 363 EP - 6 JF - Journal of clinical ultrasound : JCU JO - J Clin Ultrasound VL - 35 IS - 7 N2 - PURPOSE: To investigate the number of cores required to diagnose breast cancer using ultrasound (US)-guided core needle biopsy. METHODS: US-guided core biopsy of 150 masses was performed in 144 patients. For each mass, 6 cores were obtained and analyzed separately. The histopathologic diagnosis was classified as benign, malignant, or normal breast tissue. Each core was analyzed separately. For diagnostic purposes, the cases were grouped as follows: group G1 comprised the first core; group G2 comprised the first and second core; group G3 comprised the first 3 cores; up to group G6, which included all 6 cores. The results were also analyzed by tumor size (</=2 cm and >2 cm). RESULTS: The sensitivity in the diagnosis of breast cancer was 90.1% in group G1 and 94.1% in the remaining groups (G2-G6). In tumors </=2 cm, the sensitivity was 88.4% for group G1 and 90.7% for the others, whereas for tumors >2 cm the sensitivity was 91.4% for group G1 and 96.6% when 2 or more cores were obtained. CONCLUSION: It appears that 2 cores are sufficient to diagnose breast cancer in this study population assuming no technical error occurred in US guidance of the needle through the mass. SN - 0091-2751 UR - https://www.unboundmedicine.com/medline/citation/17663457/Ultrasound_guided_core_needle_biopsy_of_breast_masses:_How_many_cores_are_necessary_to_diagnose_cancer L2 - https://doi.org/10.1002/jcu.20380 DB - PRIME DP - Unbound Medicine ER -