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[Levels of C-reactive protein and antibodies against oxidized low-density lipoprotein in patients with different types of coronary heart disease].
Nan Fang Yi Ke Da Xue Xue Bao 2007; 27(7):1068-70NF

Abstract

OBJECTIVE

To investigate the relation of the levels of C-reactive protein (CRP) and antibodies against oxidized low-density lipoprotein (anti-oxLDL) to with acute coronary syndrome (ACS).

METHODS

The levels of CRP, anti-oxLDL and anti-LDL were measured and compared in 96 subjects including 26 with acute myocardial infarction (AMI), 29 with unstable angina pectoris (UAP), 20 with stable angina pectoris (SAP) and 21 control subjects to evaluate the relationship between CRP and anti-oxLDL.

RESULTS

Both CRP and anti-oxLDL levels in patients with ACS, including AMI and UAP, were significantly higher than those in SAP patients and the control subjects (P<0.05), but the level of anti-LDL showed no significant difference between the groups (P>0.05). There was significant positive correlation between the levels of CRP and anti-oxLDL (P<0.001).

CONCLUSION

The specific immune response to oxLDL may play an important role in the instability of plaque and the occurrence of ACS, and anti-oxLDL level may serve as an important specific marker for the instability of plaque.

Authors+Show Affiliations

Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. maliqin@fimmu.com

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

17666352

Citation

Ma, Li-qin, et al. "[Levels of C-reactive Protein and Antibodies Against Oxidized Low-density Lipoprotein in Patients With Different Types of Coronary Heart Disease]." Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, vol. 27, no. 7, 2007, pp. 1068-70.
Ma LQ, Zheng H, Wu SZ. [Levels of C-reactive protein and antibodies against oxidized low-density lipoprotein in patients with different types of coronary heart disease]. Nan Fang Yi Ke Da Xue Xue Bao. 2007;27(7):1068-70.
Ma, L. Q., Zheng, H., & Wu, S. Z. (2007). [Levels of C-reactive protein and antibodies against oxidized low-density lipoprotein in patients with different types of coronary heart disease]. Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 27(7), pp. 1068-70.
Ma LQ, Zheng H, Wu SZ. [Levels of C-reactive Protein and Antibodies Against Oxidized Low-density Lipoprotein in Patients With Different Types of Coronary Heart Disease]. Nan Fang Yi Ke Da Xue Xue Bao. 2007;27(7):1068-70. PubMed PMID: 17666352.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Levels of C-reactive protein and antibodies against oxidized low-density lipoprotein in patients with different types of coronary heart disease]. AU - Ma,Li-qin, AU - Zheng,Hua, AU - Wu,Sai-zhu, PY - 2007/8/2/pubmed PY - 2010/6/10/medline PY - 2007/8/2/entrez SP - 1068 EP - 70 JF - Nan fang yi ke da xue xue bao = Journal of Southern Medical University JO - Nan Fang Yi Ke Da Xue Xue Bao VL - 27 IS - 7 N2 - OBJECTIVE: To investigate the relation of the levels of C-reactive protein (CRP) and antibodies against oxidized low-density lipoprotein (anti-oxLDL) to with acute coronary syndrome (ACS). METHODS: The levels of CRP, anti-oxLDL and anti-LDL were measured and compared in 96 subjects including 26 with acute myocardial infarction (AMI), 29 with unstable angina pectoris (UAP), 20 with stable angina pectoris (SAP) and 21 control subjects to evaluate the relationship between CRP and anti-oxLDL. RESULTS: Both CRP and anti-oxLDL levels in patients with ACS, including AMI and UAP, were significantly higher than those in SAP patients and the control subjects (P<0.05), but the level of anti-LDL showed no significant difference between the groups (P>0.05). There was significant positive correlation between the levels of CRP and anti-oxLDL (P<0.001). CONCLUSION: The specific immune response to oxLDL may play an important role in the instability of plaque and the occurrence of ACS, and anti-oxLDL level may serve as an important specific marker for the instability of plaque. SN - 1673-4254 UR - https://www.unboundmedicine.com/medline/citation/17666352/[Levels_of_C_reactive_protein_and_antibodies_against_oxidized_low_density_lipoprotein_in_patients_with_different_types_of_coronary_heart_disease]_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -