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[Fingerprint analysis of Luotong capsule by HPLC].
Zhong Yao Cai. 2007 Apr; 30(4):460-3.ZY

Abstract

OBJECTIVE

To develop the chromatographic fingerprints of Luotong capsule by HPLC.

METHODS

The separation was performed on YMC-PacK ODS (4.6 mm x 250 mm, 5 microm) column with a mobile phase consisting of acetonitrile -0.5% phosphoric acid as gradient elution at the flow rate of 1.0 ml/min. The detective wavelength was 276 nm. The column temperature was 30 degrees C.

RESULTS

A standard HPLC fingerprint procedure was developed for Luotong capsule with 18 common peaks. The similarity of 10 batches of Luotong capsule was not lower than 0.978.

CONCLUSION

The mehtod is accurate, repeatable and useful for the quality control of Luotong capsule.

Authors+Show Affiliations

Zhao XL
Institue of TCM, Nanjing University of Traitional Chinese Medicine, Nanjing 210029, China. xlee_zhao@163.com
Di LQ
No affiliation info available
Wu H
No affiliation info available
Li WD
No affiliation info available

MeSH

CapsulesChromatography, High Pressure LiquidDrug CombinationsDrug StabilityDrugs, Chinese HerbalMethanolQuality ControlReproducibility of Results

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

17674803

Citation

Zhao, Xiao-li, et al. "[Fingerprint Analysis of Luotong Capsule By HPLC]." Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, vol. 30, no. 4, 2007, pp. 460-3.
Zhao XL, Di LQ, Wu H, et al. [Fingerprint analysis of Luotong capsule by HPLC]. Zhong Yao Cai. 2007;30(4):460-3.
Zhao, X. L., Di, L. Q., Wu, H., & Li, W. D. (2007). [Fingerprint analysis of Luotong capsule by HPLC]. Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials, 30(4), 460-3.
Zhao XL, et al. [Fingerprint Analysis of Luotong Capsule By HPLC]. Zhong Yao Cai. 2007;30(4):460-3. PubMed PMID: 17674803.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Fingerprint analysis of Luotong capsule by HPLC]. AU - Zhao,Xiao-li, AU - Di,Liu-qing, AU - Wu,Hao, AU - Li,Wei-dong, PY - 2007/8/7/pubmed PY - 2008/10/31/medline PY - 2007/8/7/entrez SP - 460 EP - 3 JF - Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials JO - Zhong Yao Cai VL - 30 IS - 4 N2 - OBJECTIVE: To develop the chromatographic fingerprints of Luotong capsule by HPLC. METHODS: The separation was performed on YMC-PacK ODS (4.6 mm x 250 mm, 5 microm) column with a mobile phase consisting of acetonitrile -0.5% phosphoric acid as gradient elution at the flow rate of 1.0 ml/min. The detective wavelength was 276 nm. The column temperature was 30 degrees C. RESULTS: A standard HPLC fingerprint procedure was developed for Luotong capsule with 18 common peaks. The similarity of 10 batches of Luotong capsule was not lower than 0.978. CONCLUSION: The mehtod is accurate, repeatable and useful for the quality control of Luotong capsule. SN - 1001-4454 UR - https://www.unboundmedicine.com/medline/citation/17674803/[Fingerprint_analysis_of_Luotong_capsule_by_HPLC]_ DB - PRIME DP - Unbound Medicine ER -