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Composition and antifungal activity of the essential oil of Mentha cervina from Portugal.
Nat Prod Res. 2007 Aug; 21(10):867-71.NP

Abstract

The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervina collected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9-79.6%) and isomenthone (8.7-77.0%). Antifungal activity of the oils was evaluated by minimal inhibitory concentrations (MIC) and minimal lethal concentrations (MLC) against Candida, Apergillus and dermatophyte strains. Antifungal activity of the sample containing lower amounts of pulegone was the highest for dermatophytes, particularly for Epidermophyton floccosum with MIC and MLC values of 0.63 microL mL(- 1). Mentha cervina oils with low content of pulegone, may be an alternative as antifungal agents in dermatophytosis.

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Authors+Show Affiliations

Gonçalves MJ
Laboratório de Farmacognosia/CEF, Faculdade de Farmácia, Universidade de Coimbra, 3000-295 Coimbra, Portugal.
Vicente AM
No affiliation info available
Cavaleiro C
No affiliation info available
Salgueiro L
No affiliation info available

MeSH

Antifungal AgentsAspergillusCandidaHumansMedicine, TraditionalMenthaMicrobial Sensitivity TestsPhytotherapyPlant OilsPortugal

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17680495

Citation

Gonçalves, M J., et al. "Composition and Antifungal Activity of the Essential Oil of Mentha Cervina From Portugal." Natural Product Research, vol. 21, no. 10, 2007, pp. 867-71.
Gonçalves MJ, Vicente AM, Cavaleiro C, et al. Composition and antifungal activity of the essential oil of Mentha cervina from Portugal. Nat Prod Res. 2007;21(10):867-71.
Gonçalves, M. J., Vicente, A. M., Cavaleiro, C., & Salgueiro, L. (2007). Composition and antifungal activity of the essential oil of Mentha cervina from Portugal. Natural Product Research, 21(10), 867-71.
Gonçalves MJ, et al. Composition and Antifungal Activity of the Essential Oil of Mentha Cervina From Portugal. Nat Prod Res. 2007;21(10):867-71. PubMed PMID: 17680495.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition and antifungal activity of the essential oil of Mentha cervina from Portugal. AU - Gonçalves,M J, AU - Vicente,A M, AU - Cavaleiro,C, AU - Salgueiro,L, PY - 2007/8/8/pubmed PY - 2007/11/1/medline PY - 2007/8/8/entrez SP - 867 EP - 71 JF - Natural product research JO - Nat Prod Res VL - 21 IS - 10 N2 - The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervina collected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9-79.6%) and isomenthone (8.7-77.0%). Antifungal activity of the oils was evaluated by minimal inhibitory concentrations (MIC) and minimal lethal concentrations (MLC) against Candida, Apergillus and dermatophyte strains. Antifungal activity of the sample containing lower amounts of pulegone was the highest for dermatophytes, particularly for Epidermophyton floccosum with MIC and MLC values of 0.63 microL mL(- 1). Mentha cervina oils with low content of pulegone, may be an alternative as antifungal agents in dermatophytosis. SN - 1478-6419 UR - https://www.unboundmedicine.com/medline/citation/17680495/Composition_and_antifungal_activity_of_the_essential_oil_of_Mentha_cervina_from_Portugal_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410701482244 DB - PRIME DP - Unbound Medicine ER -