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Practical approaches of taste masking technologies in oral solid forms.
Expert Opin Drug Deliv. 2007 Jul; 4(4):417-26.EO

Abstract

In the pharmaceutical industry, taste masking techniques are applied to prevent active pharmaceutical ingredients exhibiting a bitter and unpleasant taste. The oral administration of bitter drugs through solid dosage forms requires an acceptable degree of palatability, patient tolerance and significant therapeutic value. In the recent years, enormous progress in taste masking technologies has given rise to novel strategies such as fast dissolving dosage forms, chewable tablets and coating of molten materials. Similarly, common technologies applying double coating layers, microencapsulation or even chemical modification have been employed to improve patient compliance. This review endeavours to present the practical technologies and platforms applied for taste masking and indicate the most interesting features of each approach.

Authors+Show Affiliations

Phoqus Pharmaceutical Limited, 10 Kings Hill Avenue, Kings Hill, West Malling, ME19 4PQ, Kent, UK. dionysios.douroumis@phoqus.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17683254

Citation

Douroumis, Dionysios. "Practical Approaches of Taste Masking Technologies in Oral Solid Forms." Expert Opinion On Drug Delivery, vol. 4, no. 4, 2007, pp. 417-26.
Douroumis D. Practical approaches of taste masking technologies in oral solid forms. Expert Opin Drug Deliv. 2007;4(4):417-26.
Douroumis, D. (2007). Practical approaches of taste masking technologies in oral solid forms. Expert Opinion On Drug Delivery, 4(4), 417-26.
Douroumis D. Practical Approaches of Taste Masking Technologies in Oral Solid Forms. Expert Opin Drug Deliv. 2007;4(4):417-26. PubMed PMID: 17683254.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Practical approaches of taste masking technologies in oral solid forms. A1 - Douroumis,Dionysios, PY - 2007/8/9/pubmed PY - 2007/9/19/medline PY - 2007/8/9/entrez SP - 417 EP - 26 JF - Expert opinion on drug delivery JO - Expert Opin Drug Deliv VL - 4 IS - 4 N2 - In the pharmaceutical industry, taste masking techniques are applied to prevent active pharmaceutical ingredients exhibiting a bitter and unpleasant taste. The oral administration of bitter drugs through solid dosage forms requires an acceptable degree of palatability, patient tolerance and significant therapeutic value. In the recent years, enormous progress in taste masking technologies has given rise to novel strategies such as fast dissolving dosage forms, chewable tablets and coating of molten materials. Similarly, common technologies applying double coating layers, microencapsulation or even chemical modification have been employed to improve patient compliance. This review endeavours to present the practical technologies and platforms applied for taste masking and indicate the most interesting features of each approach. SN - 1742-5247 UR - https://www.unboundmedicine.com/medline/citation/17683254/Practical_approaches_of_taste_masking_technologies_in_oral_solid_forms_ L2 - http://www.tandfonline.com/doi/full/10.1517/17425247.4.4.417 DB - PRIME DP - Unbound Medicine ER -