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[Long-term prognosis after coronary revascularization in patients with end-stage renal disease on dialysis: comparison of percutaneous coronary intervention and coronary artery bypass grafting].
J Cardiol. 2007 Jul; 50(1):11-20.JC

Abstract

OBJECTIVES

To investigate the optimal method of coronary revascularization in patients on dialysis.

METHODS

We retrospectively analyzed 145 patients on dialysis who underwent percutaneous coronary intervention (PCI) (81 patients) or coronary artery bypass grafting (CABG) (64 patients). Survival and non-fatal cardiac event-free rates were compared between the two groups by the Kaplan-Meier method. The impact of independent predictors on survival and non-fatal cardiac event-free rates were examined by the Cox regression model.

RESULTS

The number of diseased vessels was smaller and ejection fraction was greater in the PCI group compared with the CABG group (1.74 +/- 0.67 vs 2.56 +/- 0.61, p < 0.0001 and 61.1 +/- 14.3% vs 50.6 +/- 17.4%, p = 0.001). The 1-year and 5-year survival rates of the PCI group were significantly higher than those of the CABG group (93.8 +/- 2.7% and 66.6 +/- 5.7% vs 76.0 +/- 5.4% and 44.8 +/- 6.5%, p = 0.0065). However, CABG was not an independent predictor of death by multivariate analysis (p = 0.06). The 1-year and 5-year non-fatal cardiac event-free rates of the PCI group were significantly lower than those of the CABG group (63.7 +/- 5.4% and 34.7 +/- 5.8% vs 83.2 +/- 4.9% and 66.8 +/- 7.4%, p = 0.0003). PCI was an independent predictor of non-fatal cardiac event by multivariate analysis (p = 0.007).

CONCLUSIONS

PCI was associated with a higher incidence of non-fatal cardiac events, but survival rate was better after PCI than after CABG. PCI is very important and acceptable as a method of coronary revascularization in patients on dialysis.

Authors+Show Affiliations

Department of Cardiovascular Center Medicine, Toranomon Hospital, Tokyo. fujimoto@toranomon.gr.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

jpn

PubMed ID

17685025

Citation

Fujimoto, Yo, et al. "[Long-term Prognosis After Coronary Revascularization in Patients With End-stage Renal Disease On Dialysis: Comparison of Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting]." Journal of Cardiology, vol. 50, no. 1, 2007, pp. 11-20.
Fujimoto Y, Ishiwata S, Dohi T, et al. [Long-term prognosis after coronary revascularization in patients with end-stage renal disease on dialysis: comparison of percutaneous coronary intervention and coronary artery bypass grafting]. J Cardiol. 2007;50(1):11-20.
Fujimoto, Y., Ishiwata, S., Dohi, T., Masuda, J., Fujimoto, H., Mitani, H., Maehara, A., Ohno, M., Yamaguchi, T., Tanaka, K., & Naruse, Y. (2007). [Long-term prognosis after coronary revascularization in patients with end-stage renal disease on dialysis: comparison of percutaneous coronary intervention and coronary artery bypass grafting]. Journal of Cardiology, 50(1), 11-20.
Fujimoto Y, et al. [Long-term Prognosis After Coronary Revascularization in Patients With End-stage Renal Disease On Dialysis: Comparison of Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting]. J Cardiol. 2007;50(1):11-20. PubMed PMID: 17685025.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Long-term prognosis after coronary revascularization in patients with end-stage renal disease on dialysis: comparison of percutaneous coronary intervention and coronary artery bypass grafting]. AU - Fujimoto,Yo, AU - Ishiwata,Sugao, AU - Dohi,Tomotaka, AU - Masuda,Jun, AU - Fujimoto,Hajime, AU - Mitani,Haruo, AU - Maehara,Akiko, AU - Ohno,Minoru, AU - Yamaguchi,Tetsu, AU - Tanaka,Keita, AU - Naruse,Yoshihiro, PY - 2007/8/10/pubmed PY - 2007/8/29/medline PY - 2007/8/10/entrez SP - 11 EP - 20 JF - Journal of cardiology JO - J Cardiol VL - 50 IS - 1 N2 - OBJECTIVES: To investigate the optimal method of coronary revascularization in patients on dialysis. METHODS: We retrospectively analyzed 145 patients on dialysis who underwent percutaneous coronary intervention (PCI) (81 patients) or coronary artery bypass grafting (CABG) (64 patients). Survival and non-fatal cardiac event-free rates were compared between the two groups by the Kaplan-Meier method. The impact of independent predictors on survival and non-fatal cardiac event-free rates were examined by the Cox regression model. RESULTS: The number of diseased vessels was smaller and ejection fraction was greater in the PCI group compared with the CABG group (1.74 +/- 0.67 vs 2.56 +/- 0.61, p < 0.0001 and 61.1 +/- 14.3% vs 50.6 +/- 17.4%, p = 0.001). The 1-year and 5-year survival rates of the PCI group were significantly higher than those of the CABG group (93.8 +/- 2.7% and 66.6 +/- 5.7% vs 76.0 +/- 5.4% and 44.8 +/- 6.5%, p = 0.0065). However, CABG was not an independent predictor of death by multivariate analysis (p = 0.06). The 1-year and 5-year non-fatal cardiac event-free rates of the PCI group were significantly lower than those of the CABG group (63.7 +/- 5.4% and 34.7 +/- 5.8% vs 83.2 +/- 4.9% and 66.8 +/- 7.4%, p = 0.0003). PCI was an independent predictor of non-fatal cardiac event by multivariate analysis (p = 0.007). CONCLUSIONS: PCI was associated with a higher incidence of non-fatal cardiac events, but survival rate was better after PCI than after CABG. PCI is very important and acceptable as a method of coronary revascularization in patients on dialysis. SN - 0914-5087 UR - https://www.unboundmedicine.com/medline/citation/17685025/[Long_term_prognosis_after_coronary_revascularization_in_patients_with_end_stage_renal_disease_on_dialysis:_comparison_of_percutaneous_coronary_intervention_and_coronary_artery_bypass_grafting]_ L2 - https://medlineplus.gov/kidneyfailure.html DB - PRIME DP - Unbound Medicine ER -