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Multiple filum terminale hemangioblastomas symptomatic during pregnancy. Case report.
J Neurosurg Spine. 2007 Aug; 7(2):254-8.JN

Abstract

Hemangioblastomas are low-grade, highly vascular tumors commonly associated with von Hippel-Lindau (VHL) syndrome and most often appearing in the cerebellum. They very rarely occur in the spinal nerve roots, and an origin in the filum terminale is exceptional with no instances of multiple hemangioblastomas of the filum terminale reported in the literature. Because of their vascular nature, these lesions can enlarge and become symptomatic in the context of the changes that take place during pregnancy, as has been noted with cerebellar hemangioblastomas. In any case, the evolution of spinal hemangioblastomas during pregnancy is not well known given its rarity. The conjunction of both processes--that is, multiple hemangioblastomas arising in the filum terminale and pregnancy--is unique. The authors describe the case of a 41-year-old woman with multiple hemangioblastomas of the filum terminale and no other evidence of VHL syndrome, in whom pregnancy precipitated symptoms. The interruption of gestation led to a remission of the symptoms. The literature concerning filum terminale hemangioblastomas and pregnancy is also reviewed.

Authors+Show Affiliations

Neurosurgical Service, Hospital Regional Universitario Infanta Cristina, Badajoz, Spain. marta.ort@terra.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

17688069

Citation

Ortega-Martínez, Marta, et al. "Multiple Filum Terminale Hemangioblastomas Symptomatic During Pregnancy. Case Report." Journal of Neurosurgery. Spine, vol. 7, no. 2, 2007, pp. 254-8.
Ortega-Martínez M, Cabezudo JM, Fernández-Portales I, et al. Multiple filum terminale hemangioblastomas symptomatic during pregnancy. Case report. J Neurosurg Spine. 2007;7(2):254-8.
Ortega-Martínez, M., Cabezudo, J. M., Fernández-Portales, I., Pineda-Palomo, M., Rodríguez-Sánchez, J. A., & Bernal-García, L. M. (2007). Multiple filum terminale hemangioblastomas symptomatic during pregnancy. Case report. Journal of Neurosurgery. Spine, 7(2), 254-8.
Ortega-Martínez M, et al. Multiple Filum Terminale Hemangioblastomas Symptomatic During Pregnancy. Case Report. J Neurosurg Spine. 2007;7(2):254-8. PubMed PMID: 17688069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multiple filum terminale hemangioblastomas symptomatic during pregnancy. Case report. AU - Ortega-Martínez,Marta, AU - Cabezudo,Jose M, AU - Fernández-Portales,Ignacio, AU - Pineda-Palomo,Manuel, AU - Rodríguez-Sánchez,Jose Antonio, AU - Bernal-García,Luis Miguel, PY - 2007/8/11/pubmed PY - 2007/8/24/medline PY - 2007/8/11/entrez SP - 254 EP - 8 JF - Journal of neurosurgery. Spine JO - J Neurosurg Spine VL - 7 IS - 2 N2 - Hemangioblastomas are low-grade, highly vascular tumors commonly associated with von Hippel-Lindau (VHL) syndrome and most often appearing in the cerebellum. They very rarely occur in the spinal nerve roots, and an origin in the filum terminale is exceptional with no instances of multiple hemangioblastomas of the filum terminale reported in the literature. Because of their vascular nature, these lesions can enlarge and become symptomatic in the context of the changes that take place during pregnancy, as has been noted with cerebellar hemangioblastomas. In any case, the evolution of spinal hemangioblastomas during pregnancy is not well known given its rarity. The conjunction of both processes--that is, multiple hemangioblastomas arising in the filum terminale and pregnancy--is unique. The authors describe the case of a 41-year-old woman with multiple hemangioblastomas of the filum terminale and no other evidence of VHL syndrome, in whom pregnancy precipitated symptoms. The interruption of gestation led to a remission of the symptoms. The literature concerning filum terminale hemangioblastomas and pregnancy is also reviewed. SN - 1547-5654 UR - https://www.unboundmedicine.com/medline/citation/17688069/Multiple_filum_terminale_hemangioblastomas_symptomatic_during_pregnancy__Case_report_ L2 - https://thejns.org/doi/10.3171/SPI-07/08/254 DB - PRIME DP - Unbound Medicine ER -