Tags

Type your tag names separated by a space and hit enter

"Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs).
Clin Pharmacol Ther. 2007 Sep; 82(3):241-3.CP

Abstract

There has recently been an explosion of interest in adult stem/progenitor cells that have the potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous announcements of clinical trials in which the cells are used to treat individuals with a broad range of diseases. At the same time, the data present a paradox-the cells originally attracted attention because of their stem-cell-like properties, but the cells frequently repair injured tissues without much evidence of either engraftment or differentiation.

Authors+Show Affiliations

Tulane Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, Louisiana, USA. dprocko@tulane.edu

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17700588

Citation

Prockop, D J.. ""Stemness" Does Not Explain the Repair of Many Tissues By Mesenchymal Stem/multipotent Stromal Cells (MSCs)." Clinical Pharmacology and Therapeutics, vol. 82, no. 3, 2007, pp. 241-3.
Prockop DJ. "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). Clin Pharmacol Ther. 2007;82(3):241-3.
Prockop, D. J. (2007). "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). Clinical Pharmacology and Therapeutics, 82(3), 241-3.
Prockop DJ. "Stemness" Does Not Explain the Repair of Many Tissues By Mesenchymal Stem/multipotent Stromal Cells (MSCs). Clin Pharmacol Ther. 2007;82(3):241-3. PubMed PMID: 17700588.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - "Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs). A1 - Prockop,D J, PY - 2007/8/19/pubmed PY - 2007/9/27/medline PY - 2007/8/19/entrez SP - 241 EP - 3 JF - Clinical pharmacology and therapeutics JO - Clin. Pharmacol. Ther. VL - 82 IS - 3 N2 - There has recently been an explosion of interest in adult stem/progenitor cells that have the potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous announcements of clinical trials in which the cells are used to treat individuals with a broad range of diseases. At the same time, the data present a paradox-the cells originally attracted attention because of their stem-cell-like properties, but the cells frequently repair injured tissues without much evidence of either engraftment or differentiation. SN - 0009-9236 UR - https://www.unboundmedicine.com/medline/citation/17700588/"Stemness"_does_not_explain_the_repair_of_many_tissues_by_mesenchymal_stem/multipotent_stromal_cells__MSCs__ L2 - https://doi.org/10.1038/sj.clpt.6100313 DB - PRIME DP - Unbound Medicine ER -