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[Diagnostic difficulties in neuroborreliosis in children].
Przegl Epidemiol. 2007; 61(1):73-8.PE

Abstract

OBJECTIVE

Analysis of clinical picture in children hospitalized because of suspicion of neuroborreliosis and evaluation of usefulness of testing serum and cerebrospinal fluid (CSF) for specific antibodies.

MATERIAL AND METHODS

23 children (age: 13 months - 15.5 years) were hospitalized: 11 children with facial palsy, 2 children with radiculopathy and 10 children with headache. In 21 children lumbar puncture and CSF examination was done. Serum of all children and CSF of 21 children were tested by ELISA for specific antibodies (IDEIA DakoCytomation).

RESULTS

Meningeal signs in physical examination were found in 4 children and inflammatory CSF changes in 8 children. Specific antibodies in sera of 19 children and in CSF of 7 children. Neuroborreliosis was diagnosed in 12 children: in 9 facial palsy (in 6 with inflammatory CSF changes), in 2 Bannwarth's syndrome and in 1 aseptic meningitis. Diagnosis was confirmed by detection of specific antibodies in sera of 10 children and in CSF of 6 children.

CONCLUSIONS

Meningitis in the course of neuroborreliosis is not always accompanied by meningeal signs. Positive serology is not an unequivocal confirmation of neuroborreliosis especially if symptoms are nonspecific (e.g. headache).

Authors+Show Affiliations

Klinika Chorób Zakaźnych Wieku Dzieciecego AM w Warszawie.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

pol

PubMed ID

17702442

Citation

Talarek, Ewa, et al. "[Diagnostic Difficulties in Neuroborreliosis in Children]." Przeglad Epidemiologiczny, vol. 61, no. 1, 2007, pp. 73-8.
Talarek E, Duszczyk E, Zarnowska H. [Diagnostic difficulties in neuroborreliosis in children]. Przegl Epidemiol. 2007;61(1):73-8.
Talarek, E., Duszczyk, E., & Zarnowska, H. (2007). [Diagnostic difficulties in neuroborreliosis in children]. Przeglad Epidemiologiczny, 61(1), 73-8.
Talarek E, Duszczyk E, Zarnowska H. [Diagnostic Difficulties in Neuroborreliosis in Children]. Przegl Epidemiol. 2007;61(1):73-8. PubMed PMID: 17702442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Diagnostic difficulties in neuroborreliosis in children]. AU - Talarek,Ewa, AU - Duszczyk,Ewa, AU - Zarnowska,Hanna, PY - 2007/8/19/pubmed PY - 2007/10/12/medline PY - 2007/8/19/entrez SP - 73 EP - 8 JF - Przeglad epidemiologiczny JO - Przegl Epidemiol VL - 61 IS - 1 N2 - OBJECTIVE: Analysis of clinical picture in children hospitalized because of suspicion of neuroborreliosis and evaluation of usefulness of testing serum and cerebrospinal fluid (CSF) for specific antibodies. MATERIAL AND METHODS: 23 children (age: 13 months - 15.5 years) were hospitalized: 11 children with facial palsy, 2 children with radiculopathy and 10 children with headache. In 21 children lumbar puncture and CSF examination was done. Serum of all children and CSF of 21 children were tested by ELISA for specific antibodies (IDEIA DakoCytomation). RESULTS: Meningeal signs in physical examination were found in 4 children and inflammatory CSF changes in 8 children. Specific antibodies in sera of 19 children and in CSF of 7 children. Neuroborreliosis was diagnosed in 12 children: in 9 facial palsy (in 6 with inflammatory CSF changes), in 2 Bannwarth's syndrome and in 1 aseptic meningitis. Diagnosis was confirmed by detection of specific antibodies in sera of 10 children and in CSF of 6 children. CONCLUSIONS: Meningitis in the course of neuroborreliosis is not always accompanied by meningeal signs. Positive serology is not an unequivocal confirmation of neuroborreliosis especially if symptoms are nonspecific (e.g. headache). SN - 0033-2100 UR - https://www.unboundmedicine.com/medline/citation/17702442/[Diagnostic_difficulties_in_neuroborreliosis_in_children]_ DB - PRIME DP - Unbound Medicine ER -