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Antimicrobial treatment of sinusitis.
Semin Respir Infect. 1991 Jun; 6(2):77-84.SR

Abstract

Sinusitis is a common disease. Most cases of acute sinusitis involve the maxillary sinus and occur after viral infections of the upper respiratory tract. The usual pathogens are Streptococcus pneumoniae and Haemophilus influenzae. Moraxella (Branhamella) catarrhalis is also an important pathogen in children. Anaerobic infections are more common in chronic sinusitis. Fungi are frequently observed in granulocytopenic cancer patients but also can occur in apparently normal hosts. Many strains of H influenzae and M catarrhalis observed in patients with sinusitis produce beta-lactamases. Many antimicrobial regimens have proven successful in the treatment of sinusitis, including ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, the tetracyclines, and cefuroxime axetil, but only the latter three drugs are active against most beta-lactamase-producing strains. Nosocomial sinusitis usually occurs in intensive care unit settings and is frequently associated with nasopharyngeal instrumentation. The pathogens observed in nosocomial sinusitis are gram-negative bacilli or staphylococci and frequently require therapy with broad-spectrum penicillins or cephalosporins, an aminoglycoside, or vancomycin.

Authors+Show Affiliations

Bamberger DM
School of Medicine, University of Missouri, Kansas City 64108.

MeSH

Anti-Bacterial AgentsBacterial InfectionsChronic DiseaseHaemophilus InfectionsHaemophilus influenzaeHumansMaxillary SinusitisMoraxella catarrhalisNeisseriaceae InfectionsPneumococcal Infections

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

1771306

Citation

Bamberger, D M.. "Antimicrobial Treatment of Sinusitis." Seminars in Respiratory Infections, vol. 6, no. 2, 1991, pp. 77-84.
Bamberger DM. Antimicrobial treatment of sinusitis. Semin Respir Infect. 1991;6(2):77-84.
Bamberger, D. M. (1991). Antimicrobial treatment of sinusitis. Seminars in Respiratory Infections, 6(2), 77-84.
Bamberger DM. Antimicrobial Treatment of Sinusitis. Semin Respir Infect. 1991;6(2):77-84. PubMed PMID: 1771306.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial treatment of sinusitis. A1 - Bamberger,D M, PY - 1991/6/1/pubmed PY - 1991/6/1/medline PY - 1991/6/1/entrez SP - 77 EP - 84 JF - Seminars in respiratory infections JO - Semin Respir Infect VL - 6 IS - 2 N2 - Sinusitis is a common disease. Most cases of acute sinusitis involve the maxillary sinus and occur after viral infections of the upper respiratory tract. The usual pathogens are Streptococcus pneumoniae and Haemophilus influenzae. Moraxella (Branhamella) catarrhalis is also an important pathogen in children. Anaerobic infections are more common in chronic sinusitis. Fungi are frequently observed in granulocytopenic cancer patients but also can occur in apparently normal hosts. Many strains of H influenzae and M catarrhalis observed in patients with sinusitis produce beta-lactamases. Many antimicrobial regimens have proven successful in the treatment of sinusitis, including ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, the tetracyclines, and cefuroxime axetil, but only the latter three drugs are active against most beta-lactamase-producing strains. Nosocomial sinusitis usually occurs in intensive care unit settings and is frequently associated with nasopharyngeal instrumentation. The pathogens observed in nosocomial sinusitis are gram-negative bacilli or staphylococci and frequently require therapy with broad-spectrum penicillins or cephalosporins, an aminoglycoside, or vancomycin. SN - 0882-0546 UR - https://www.unboundmedicine.com/medline/citation/1771306/Antimicrobial_treatment_of_sinusitis_ DB - PRIME DP - Unbound Medicine ER -