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Identification and characterization of SMI32-immunoreactive amacrine cells in the mouse retina.
Neurosci Lett 2007; 424(3):199-202NL

Abstract

Mammalian neurons express the neural intermediate filament protein neurofilament (NF). In the retina, NFs have been detected primarily in the axons and processes of retinal ganglion and horizontal cells. We found an amacrine cell type that was immunolabeled with an antibody against SMI32, a non-phosphorylated epitope on neurofilament proteins of high molecular weight, in the mouse retina. This type of amacrine cell was non-randomly distributed, and these cells exhibited a central-peripheral density gradient. Most of these cells co-expressed GABA and ChAT, but not glycine or any other amacrine cell marker. These results suggest that some SMI32-immunoreactive amacrine cells belong to a GABAergic population, and that SMI32 can therefore be used as a marker for a subset of amacrine cells in addition to ganglion cells and horizontal cells in the mouse retina.

Authors+Show Affiliations

Department of Anatomy, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Socho-gu, Seoul 137-701, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17723270

Citation

Lim, Eun-Jin, et al. "Identification and Characterization of SMI32-immunoreactive Amacrine Cells in the Mouse Retina." Neuroscience Letters, vol. 424, no. 3, 2007, pp. 199-202.
Lim EJ, Kim IB, Oh SJ, et al. Identification and characterization of SMI32-immunoreactive amacrine cells in the mouse retina. Neurosci Lett. 2007;424(3):199-202.
Lim, E. J., Kim, I. B., Oh, S. J., & Chun, M. H. (2007). Identification and characterization of SMI32-immunoreactive amacrine cells in the mouse retina. Neuroscience Letters, 424(3), pp. 199-202.
Lim EJ, et al. Identification and Characterization of SMI32-immunoreactive Amacrine Cells in the Mouse Retina. Neurosci Lett. 2007 Sep 13;424(3):199-202. PubMed PMID: 17723270.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Identification and characterization of SMI32-immunoreactive amacrine cells in the mouse retina. AU - Lim,Eun-Jin, AU - Kim,In-Beom, AU - Oh,Su-Ja, AU - Chun,Myung-Hoon, Y1 - 2007/08/08/ PY - 2007/05/28/received PY - 2007/07/10/revised PY - 2007/07/29/accepted PY - 2007/8/29/pubmed PY - 2008/1/5/medline PY - 2007/8/29/entrez SP - 199 EP - 202 JF - Neuroscience letters JO - Neurosci. Lett. VL - 424 IS - 3 N2 - Mammalian neurons express the neural intermediate filament protein neurofilament (NF). In the retina, NFs have been detected primarily in the axons and processes of retinal ganglion and horizontal cells. We found an amacrine cell type that was immunolabeled with an antibody against SMI32, a non-phosphorylated epitope on neurofilament proteins of high molecular weight, in the mouse retina. This type of amacrine cell was non-randomly distributed, and these cells exhibited a central-peripheral density gradient. Most of these cells co-expressed GABA and ChAT, but not glycine or any other amacrine cell marker. These results suggest that some SMI32-immunoreactive amacrine cells belong to a GABAergic population, and that SMI32 can therefore be used as a marker for a subset of amacrine cells in addition to ganglion cells and horizontal cells in the mouse retina. SN - 0304-3940 UR - https://www.unboundmedicine.com/medline/citation/17723270/Identification_and_characterization_of_SMI32_immunoreactive_amacrine_cells_in_the_mouse_retina_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0304-3940(07)00835-X DB - PRIME DP - Unbound Medicine ER -