Tags

Type your tag names separated by a space and hit enter

Types of anemia and mortality among older disabled women living in the community: the Women's Health and Aging Study I.
Aging Clin Exp Res. 2007 Aug; 19(4):259-64.AC

Abstract

AIMS

To classify the different types of anemia among moderately to severely disabled women living in the community and examine the relationship between types of anemia and mortality.

METHODS

We studied anemia in 688 women, >or=65 years, in the Women's Health and Aging Study I, a population based study of moderately to severely disabled older women living in the community in Baltimore, Maryland. Anemia was defined by World Health Organization criteria. Causes of anemia were classified as due to nutritional deficiencies (iron, folate, and B12 deficiencies), anemia of chronic inflammation, anemia with renal disease, and unexplained anemia.

RESULTS

147 of 688 (21.4%) women were anemic (hemoglobin <12 g/dL). Of the 147 anemic women, 22 (15.0%) had anemia due to nutritional causes, 45 (30.6%) had anemia due to chronic inflammation, 29 (19.7%) had anemia and renal disease, and 51 (34.7%) had unexplained anemia. The proportions of those who died over five years among non-anemic women and women with anemia due to nutritional causes, chronic inflammation, renal disease, and unexplained anemia were 26.1%, 18.2%, 38.6%, 64.3%, and 33.3%, respectively (p<0.0001). Compared with non-anemic women, those with anemia and renal disease (HR 1.99, 95% CI 1.18-3.35, p=0.009) and anemia of chronic inflammation (HR 1.69, 95% CI 1.00-2.84, p=0.05) had higher risk of death.

CONCLUSIONS

Anemia is common among moderately to severely disabled older women living in the community, and about one-third of the anemia is unexplained. Anemia with renal disease and anemia of chronic inflammation are associated with a higher mortality.

Authors+Show Affiliations

The Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA. rdsemba@jhmi.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural

Language

eng

PubMed ID

17726354

Citation

Semba, Richard D., et al. "Types of Anemia and Mortality Among Older Disabled Women Living in the Community: the Women's Health and Aging Study I." Aging Clinical and Experimental Research, vol. 19, no. 4, 2007, pp. 259-64.
Semba RD, Ricks MO, Ferrucci L, et al. Types of anemia and mortality among older disabled women living in the community: the Women's Health and Aging Study I. Aging Clin Exp Res. 2007;19(4):259-64.
Semba, R. D., Ricks, M. O., Ferrucci, L., Xue, Q. L., Chaves, P., Fried, L. P., & Guralnik, J. M. (2007). Types of anemia and mortality among older disabled women living in the community: the Women's Health and Aging Study I. Aging Clinical and Experimental Research, 19(4), 259-64.
Semba RD, et al. Types of Anemia and Mortality Among Older Disabled Women Living in the Community: the Women's Health and Aging Study I. Aging Clin Exp Res. 2007;19(4):259-64. PubMed PMID: 17726354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Types of anemia and mortality among older disabled women living in the community: the Women's Health and Aging Study I. AU - Semba,Richard D, AU - Ricks,Michelle O, AU - Ferrucci,Luigi, AU - Xue,Qian-Li, AU - Chaves,Paulo, AU - Fried,Linda P, AU - Guralnik,Jack M, PY - 2007/8/30/pubmed PY - 2007/11/6/medline PY - 2007/8/30/entrez SP - 259 EP - 64 JF - Aging clinical and experimental research JO - Aging Clin Exp Res VL - 19 IS - 4 N2 - AIMS: To classify the different types of anemia among moderately to severely disabled women living in the community and examine the relationship between types of anemia and mortality. METHODS: We studied anemia in 688 women, >or=65 years, in the Women's Health and Aging Study I, a population based study of moderately to severely disabled older women living in the community in Baltimore, Maryland. Anemia was defined by World Health Organization criteria. Causes of anemia were classified as due to nutritional deficiencies (iron, folate, and B12 deficiencies), anemia of chronic inflammation, anemia with renal disease, and unexplained anemia. RESULTS: 147 of 688 (21.4%) women were anemic (hemoglobin <12 g/dL). Of the 147 anemic women, 22 (15.0%) had anemia due to nutritional causes, 45 (30.6%) had anemia due to chronic inflammation, 29 (19.7%) had anemia and renal disease, and 51 (34.7%) had unexplained anemia. The proportions of those who died over five years among non-anemic women and women with anemia due to nutritional causes, chronic inflammation, renal disease, and unexplained anemia were 26.1%, 18.2%, 38.6%, 64.3%, and 33.3%, respectively (p<0.0001). Compared with non-anemic women, those with anemia and renal disease (HR 1.99, 95% CI 1.18-3.35, p=0.009) and anemia of chronic inflammation (HR 1.69, 95% CI 1.00-2.84, p=0.05) had higher risk of death. CONCLUSIONS: Anemia is common among moderately to severely disabled older women living in the community, and about one-third of the anemia is unexplained. Anemia with renal disease and anemia of chronic inflammation are associated with a higher mortality. SN - 1594-0667 UR - https://www.unboundmedicine.com/medline/citation/17726354/Types_of_anemia_and_mortality_among_older_disabled_women_living_in_the_community:_the_Women's_Health_and_Aging_Study_I_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/17726354/ DB - PRIME DP - Unbound Medicine ER -