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Multiple headspace solid-phase microextraction for eliminating matrix effect in the simultaneous determination of haloanisoles and volatile phenols in wines.
J Chromatogr A. 2007 Sep 28; 1166(1-2):1-8.JC

Abstract

This paper proposes a multiple headspace solid-phase microextraction (MHS-SPME) method coupled to gas chromatography-tandem mass spectrometry detection (GC/MS/MS) for the simultaneous determination of 2,4,6-trichloroanisole, 2,3,4,6-tetrachloroanisole, pentachloroanisole, 2,4,6-tribromoanisole, 4-ethylphenol, 4-ethylguaiacol, 4-vinylphenol and 4-vinylguaiacol in wines. These compounds are involved in the presence of "cork taint" and Brett character in wines. The MHS-SPME method is a modification of SPME developed for quantitative analysis that avoids possible matrix effects based on an exhaustive analyte extraction from the sample. After demonstrating the existence of matrix effect in the analysis of the target compounds by HS-SPME with a divinylbenzene/Carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fibre, the MHS-SPME method was developed and validated. The proposed method showed satisfactory linearity, precision and detection limits, all below the odour detection thresholds of the compounds in wine matrices. Good recoveries were observed for all compounds, always above 90%, and the repeatability obtained was considered acceptable, ranging between 2 and 11%. After checking the applicability of the method by comparing the results recorded with those obtained with the standard addition method, the method was applied successfully to the analysis of wine samples. To our knowledge, this is the first time that MHS-SPME combined with GC/MS/MS has been applied to simultaneously determine haloanisoles and volatile phenols in wine.

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Authors+Show Affiliations

Pizarro C
Department of Chemistry, University of La Rioja, C/ Madre de Dios 51, 26006 Logroño, La Rioja, Spain. consuelo.pizarro@dq.unirioja.es
Pérez-del-Notario N
No affiliation info available
González-Sáiz JM
No affiliation info available

MeSH

AnisolesFood ContaminationGas Chromatography-Mass SpectrometryPhenolsSolid Phase MicroextractionTandem Mass SpectrometryVolatilizationWine

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17727868

Citation

Pizarro, C, et al. "Multiple Headspace Solid-phase Microextraction for Eliminating Matrix Effect in the Simultaneous Determination of Haloanisoles and Volatile Phenols in Wines." Journal of Chromatography. A, vol. 1166, no. 1-2, 2007, pp. 1-8.
Pizarro C, Pérez-del-Notario N, González-Sáiz JM. Multiple headspace solid-phase microextraction for eliminating matrix effect in the simultaneous determination of haloanisoles and volatile phenols in wines. J Chromatogr A. 2007;1166(1-2):1-8.
Pizarro, C., Pérez-del-Notario, N., & González-Sáiz, J. M. (2007). Multiple headspace solid-phase microextraction for eliminating matrix effect in the simultaneous determination of haloanisoles and volatile phenols in wines. Journal of Chromatography. A, 1166(1-2), 1-8.
Pizarro C, Pérez-del-Notario N, González-Sáiz JM. Multiple Headspace Solid-phase Microextraction for Eliminating Matrix Effect in the Simultaneous Determination of Haloanisoles and Volatile Phenols in Wines. J Chromatogr A. 2007 Sep 28;1166(1-2):1-8. PubMed PMID: 17727868.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multiple headspace solid-phase microextraction for eliminating matrix effect in the simultaneous determination of haloanisoles and volatile phenols in wines. AU - Pizarro,C, AU - Pérez-del-Notario,N, AU - González-Sáiz,J M, Y1 - 2007/08/17/ PY - 2007/06/15/received PY - 2007/08/01/revised PY - 2007/08/01/accepted PY - 2007/8/31/pubmed PY - 2007/11/1/medline PY - 2007/8/31/entrez SP - 1 EP - 8 JF - Journal of chromatography. A JO - J Chromatogr A VL - 1166 IS - 1-2 N2 - This paper proposes a multiple headspace solid-phase microextraction (MHS-SPME) method coupled to gas chromatography-tandem mass spectrometry detection (GC/MS/MS) for the simultaneous determination of 2,4,6-trichloroanisole, 2,3,4,6-tetrachloroanisole, pentachloroanisole, 2,4,6-tribromoanisole, 4-ethylphenol, 4-ethylguaiacol, 4-vinylphenol and 4-vinylguaiacol in wines. These compounds are involved in the presence of "cork taint" and Brett character in wines. The MHS-SPME method is a modification of SPME developed for quantitative analysis that avoids possible matrix effects based on an exhaustive analyte extraction from the sample. After demonstrating the existence of matrix effect in the analysis of the target compounds by HS-SPME with a divinylbenzene/Carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fibre, the MHS-SPME method was developed and validated. The proposed method showed satisfactory linearity, precision and detection limits, all below the odour detection thresholds of the compounds in wine matrices. Good recoveries were observed for all compounds, always above 90%, and the repeatability obtained was considered acceptable, ranging between 2 and 11%. After checking the applicability of the method by comparing the results recorded with those obtained with the standard addition method, the method was applied successfully to the analysis of wine samples. To our knowledge, this is the first time that MHS-SPME combined with GC/MS/MS has been applied to simultaneously determine haloanisoles and volatile phenols in wine. SN - 0021-9673 UR - https://www.unboundmedicine.com/medline/citation/17727868/Multiple_headspace_solid_phase_microextraction_for_eliminating_matrix_effect_in_the_simultaneous_determination_of_haloanisoles_and_volatile_phenols_in_wines_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0021-9673(07)01340-4 DB - PRIME DP - Unbound Medicine ER -

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