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Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial.
Clin Exp Hypertens. 2007 Aug; 29(6):383-94.CE

Abstract

In the setting of a six-month, open-label clinical trial, 141 consecutively enrolled, hypertensive, overweight patients were randomized to the oral ingestion of psyllium powder or guar gum 3.5 gr t.i.d., to be taken 20 min before the main two meals, or to standard diet. Both fibers improved significantly BMI, FPG, FPI, HOMA Index, HbA1c, LDL-C, and ApoB. Psyllium supplementation only exerted a significant improvement in plasma TG concentration, in SBP and DBP. In our study, six-month supplementation with psyllium fiber, but not with guar fiber nor standard diet, appears to significantly reduce both SBP and DBP in hypertensive overweight subjects.

Authors+Show Affiliations

GC Descovich Atherosclerosis Research Centre, D. Campanacci Clinical Medicine and Applied Biotechnology Dept., University of Bologna, Italy. afgcicero@cardionet.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

17729055

Citation

Cicero, Arrigo F G., et al. "Different Effect of Psyllium and Guar Dietary Supplementation On Blood Pressure Control in Hypertensive Overweight Patients: a Six-month, Randomized Clinical Trial." Clinical and Experimental Hypertension (New York, N.Y. : 1993), vol. 29, no. 6, 2007, pp. 383-94.
Cicero AF, Derosa G, Manca M, et al. Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. Clin Exp Hypertens. 2007;29(6):383-94.
Cicero, A. F., Derosa, G., Manca, M., Bove, M., Borghi, C., & Gaddi, A. V. (2007). Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. Clinical and Experimental Hypertension (New York, N.Y. : 1993), 29(6), 383-94.
Cicero AF, et al. Different Effect of Psyllium and Guar Dietary Supplementation On Blood Pressure Control in Hypertensive Overweight Patients: a Six-month, Randomized Clinical Trial. Clin Exp Hypertens. 2007;29(6):383-94. PubMed PMID: 17729055.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. AU - Cicero,Arrigo F G, AU - Derosa,Giuseppe, AU - Manca,Marco, AU - Bove,Marilisa, AU - Borghi,Claudio, AU - Gaddi,Antonio V, PY - 2007/8/31/pubmed PY - 2007/12/6/medline PY - 2007/8/31/entrez SP - 383 EP - 94 JF - Clinical and experimental hypertension (New York, N.Y. : 1993) JO - Clin Exp Hypertens VL - 29 IS - 6 N2 - In the setting of a six-month, open-label clinical trial, 141 consecutively enrolled, hypertensive, overweight patients were randomized to the oral ingestion of psyllium powder or guar gum 3.5 gr t.i.d., to be taken 20 min before the main two meals, or to standard diet. Both fibers improved significantly BMI, FPG, FPI, HOMA Index, HbA1c, LDL-C, and ApoB. Psyllium supplementation only exerted a significant improvement in plasma TG concentration, in SBP and DBP. In our study, six-month supplementation with psyllium fiber, but not with guar fiber nor standard diet, appears to significantly reduce both SBP and DBP in hypertensive overweight subjects. SN - 1064-1963 UR - https://www.unboundmedicine.com/medline/citation/17729055/Different_effect_of_psyllium_and_guar_dietary_supplementation_on_blood_pressure_control_in_hypertensive_overweight_patients:_a_six_month_randomized_clinical_trial_ L2 - https://www.tandfonline.com/doi/full/10.1080/10641960701578378 DB - PRIME DP - Unbound Medicine ER -