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[Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy].
Z Geburtshilfe Neonatol. 2007 Aug; 211(4):157-61.ZG

Abstract

BACKGROUND

Symptoms of Vitamin B (12) deficiency in infancy include growth retardation, regression of psychomotor development, muscular hypotonia and brain atrophy. Besides an inappropriate vegetarian diet of the infants, a vegan diet or a pernicious anaemia of the mother may lead to an insufficient vitamin B (12) supply of the child.

PATIENTS AND METHODS

We report here the neurological symptoms of 4 fully breast-fed infants from mothers on vegan diet or with pernicious anaemia.

DISCUSSION AND CONCLUSION

Vitamin B (12) deficiency can easily be diagnosed by detection of methylmalonic acid when measuring the organic acids in urine. Vitamin B (12) deficiency should be avoided or diagnosed as early as possible since a supplementation of mother and child can prevent neurological symptoms of the baby. Furthermore, the neurological symptoms of the infant with manifest vitamin B (12) deficiency are (partially) reversible.

Authors+Show Affiliations

Klinik für Kinder und Jugendliche, Medizinische Hochschule Hannover.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

17729202

Citation

Lücke, T, et al. "[Maternal Vitamin B12 Deficiency: Cause for Neurological Symptoms in Infancy]." Zeitschrift Fur Geburtshilfe Und Neonatologie, vol. 211, no. 4, 2007, pp. 157-61.
Lücke T, Korenke GC, Poggenburg I, et al. [Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]. Z Geburtshilfe Neonatol. 2007;211(4):157-61.
Lücke, T., Korenke, G. C., Poggenburg, I., Bentele, K. H., Das, A. M., & Hartmann, H. (2007). [Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]. Zeitschrift Fur Geburtshilfe Und Neonatologie, 211(4), 157-61.
Lücke T, et al. [Maternal Vitamin B12 Deficiency: Cause for Neurological Symptoms in Infancy]. Z Geburtshilfe Neonatol. 2007;211(4):157-61. PubMed PMID: 17729202.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Maternal vitamin B12 deficiency: cause for neurological symptoms in infancy]. AU - Lücke,T, AU - Korenke,G C, AU - Poggenburg,I, AU - Bentele,K H P, AU - Das,A M, AU - Hartmann,H, PY - 2007/8/31/pubmed PY - 2007/11/14/medline PY - 2007/8/31/entrez SP - 157 EP - 61 JF - Zeitschrift fur Geburtshilfe und Neonatologie JO - Z Geburtshilfe Neonatol VL - 211 IS - 4 N2 - BACKGROUND: Symptoms of Vitamin B (12) deficiency in infancy include growth retardation, regression of psychomotor development, muscular hypotonia and brain atrophy. Besides an inappropriate vegetarian diet of the infants, a vegan diet or a pernicious anaemia of the mother may lead to an insufficient vitamin B (12) supply of the child. PATIENTS AND METHODS: We report here the neurological symptoms of 4 fully breast-fed infants from mothers on vegan diet or with pernicious anaemia. DISCUSSION AND CONCLUSION: Vitamin B (12) deficiency can easily be diagnosed by detection of methylmalonic acid when measuring the organic acids in urine. Vitamin B (12) deficiency should be avoided or diagnosed as early as possible since a supplementation of mother and child can prevent neurological symptoms of the baby. Furthermore, the neurological symptoms of the infant with manifest vitamin B (12) deficiency are (partially) reversible. SN - 0948-2393 UR - https://www.unboundmedicine.com/medline/citation/17729202/[Maternal_vitamin_B12_deficiency:_cause_for_neurological_symptoms_in_infancy]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-981249 DB - PRIME DP - Unbound Medicine ER -