Tags

Type your tag names separated by a space and hit enter

Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nerve-sparing radical prostatectomy.
Eur Urol. 2008 Mar; 53(3):564-70.EU

Abstract

OBJECTIVES

Assess acceptance of and discontinuation rate from erectile dysfunction (ED) treatment in patients after bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP).

METHODS

We analyzed acceptance and discontinuation data of 100 consecutive, age-comparable, preoperatively self-reported potent BNSRRP patients who at the discharge from the hospital received a phosphodiesterase type 5 inhibitor (PDE5-I) prescription. Patients were informed of the pharmacokinetic properties of the available compounds and the option of on-demand versus rehabilitative therapy. Thereafter, patients did not receive any specific counseling throughout the entire follow-up period and freely decided to use or not use any ED therapy. Complete preoperative data were obtained on hospital admission and included a medical and sexual history and the International Index of Erectile Function (IIEF). The IIEF was completed every 6 mo postoperatively, and patients participated in a semi-structured interview about the treatment adherence at the 18-mo follow-up.

RESULTS

Forty-nine (49%) patients freely decided not to start any ED therapy (group 1). Of the remaining patients, 36 (36%) opted for an as-needed PDE5-I (group 2), whereas 15 (15%) decided to use a daily PDE5-I (group 3). At the 18-mo follow-up, the overall discontinuation rate from both treatment modalities was 72.6% (eg, 72.2% vs. 73.3% in group 2 vs. group 3; p=0.79). Treatment effect below expectations was the main reason for treatment discontinuation, followed by loss of interest in sex due to partner's causes.

CONCLUSIONS

Almost 50% of BNSRRP patients freely decided not to start any ED treatment postoperatively. Roughly 73% of patients who started therapy eventually discontinued it.

Authors+Show Affiliations

Department of Urology, University Vita-Salute San Raffaele, Scientific Institute H. San Raffaele, Milan, Italy. salonia.andrea@hsr.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17761385

Citation

Salonia, Andrea, et al. "Acceptance of and Discontinuation Rate From Erectile Dysfunction Oral Treatment in Patients Following Bilateral Nerve-sparing Radical Prostatectomy." European Urology, vol. 53, no. 3, 2008, pp. 564-70.
Salonia A, Gallina A, Zanni G, et al. Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nerve-sparing radical prostatectomy. Eur Urol. 2008;53(3):564-70.
Salonia, A., Gallina, A., Zanni, G., Briganti, A., Dehò, F., Saccà, A., Suardi, N., Barbieri, L., Guazzoni, G., Rigatti, P., & Montorsi, F. (2008). Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nerve-sparing radical prostatectomy. European Urology, 53(3), 564-70.
Salonia A, et al. Acceptance of and Discontinuation Rate From Erectile Dysfunction Oral Treatment in Patients Following Bilateral Nerve-sparing Radical Prostatectomy. Eur Urol. 2008;53(3):564-70. PubMed PMID: 17761385.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acceptance of and discontinuation rate from erectile dysfunction oral treatment in patients following bilateral nerve-sparing radical prostatectomy. AU - Salonia,Andrea, AU - Gallina,Andrea, AU - Zanni,Giuseppe, AU - Briganti,Alberto, AU - Dehò,Federico, AU - Saccà,Antonino, AU - Suardi,Nazareno, AU - Barbieri,Luigi, AU - Guazzoni,Giorgio, AU - Rigatti,Patrizio, AU - Montorsi,Francesco, Y1 - 2007/08/20/ PY - 2007/06/30/received PY - 2007/08/07/accepted PY - 2007/9/1/pubmed PY - 2008/5/14/medline PY - 2007/9/1/entrez SP - 564 EP - 70 JF - European urology JO - Eur Urol VL - 53 IS - 3 N2 - OBJECTIVES: Assess acceptance of and discontinuation rate from erectile dysfunction (ED) treatment in patients after bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). METHODS: We analyzed acceptance and discontinuation data of 100 consecutive, age-comparable, preoperatively self-reported potent BNSRRP patients who at the discharge from the hospital received a phosphodiesterase type 5 inhibitor (PDE5-I) prescription. Patients were informed of the pharmacokinetic properties of the available compounds and the option of on-demand versus rehabilitative therapy. Thereafter, patients did not receive any specific counseling throughout the entire follow-up period and freely decided to use or not use any ED therapy. Complete preoperative data were obtained on hospital admission and included a medical and sexual history and the International Index of Erectile Function (IIEF). The IIEF was completed every 6 mo postoperatively, and patients participated in a semi-structured interview about the treatment adherence at the 18-mo follow-up. RESULTS: Forty-nine (49%) patients freely decided not to start any ED therapy (group 1). Of the remaining patients, 36 (36%) opted for an as-needed PDE5-I (group 2), whereas 15 (15%) decided to use a daily PDE5-I (group 3). At the 18-mo follow-up, the overall discontinuation rate from both treatment modalities was 72.6% (eg, 72.2% vs. 73.3% in group 2 vs. group 3; p=0.79). Treatment effect below expectations was the main reason for treatment discontinuation, followed by loss of interest in sex due to partner's causes. CONCLUSIONS: Almost 50% of BNSRRP patients freely decided not to start any ED treatment postoperatively. Roughly 73% of patients who started therapy eventually discontinued it. SN - 0302-2838 UR - https://www.unboundmedicine.com/medline/citation/17761385/Acceptance_of_and_discontinuation_rate_from_erectile_dysfunction_oral_treatment_in_patients_following_bilateral_nerve_sparing_radical_prostatectomy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0302-2838(07)01043-3 DB - PRIME DP - Unbound Medicine ER -