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Etiology of travel-related fever.
Curr Opin Infect Dis. 2007 Oct; 20(5):449-53.CO

Abstract

PURPOSE OF REVIEW

Many potentially life-threatening infections cause fever. Several recent large studies help to define causes of fever in returned travelers.

RECENT FINDINGS

The destination of travel determines the relative likelihood of the different major causes of fever. Systemic febrile illness occurs disproportionately among ill travelers returning from sub-Saharan Africa. Malaria remains the most important overall cause of systemic febrile illness in travelers to tropical regions; dengue fever is now the most prominent cause of fever in travelers to certain regions, most notably Asia. Chikungunya fever has emerged as a major cause of fever in travelers to Indian Ocean islands off Africa and to India itself. Causes of fever vary by the time of presentation after travel. Vivax malaria is an important cause of fever with onset more than a month after return; recently studies have shown that parasites causing relapse are genetically distinct from those causing primary infection. At expert referral centers up to 25% of febrile patients have no specific cause of fever determined.

SUMMARY

Knowledge of predominant causes of febrile infections by geographic region, traveler characteristics, and time of presentation can assist the clinician in guiding posttravel diagnosis and empiric therapy of ill returned travelers and is also valuable in pretravel preparation.

Authors+Show Affiliations

Harvard Medical School, Boston, Massachusetts, USA. mary_wilson@harvard.eduNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17762776

Citation

Wilson, Mary E., and David O. Freedman. "Etiology of Travel-related Fever." Current Opinion in Infectious Diseases, vol. 20, no. 5, 2007, pp. 449-53.
Wilson ME, Freedman DO. Etiology of travel-related fever. Curr Opin Infect Dis. 2007;20(5):449-53.
Wilson, M. E., & Freedman, D. O. (2007). Etiology of travel-related fever. Current Opinion in Infectious Diseases, 20(5), 449-53.
Wilson ME, Freedman DO. Etiology of Travel-related Fever. Curr Opin Infect Dis. 2007;20(5):449-53. PubMed PMID: 17762776.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Etiology of travel-related fever. AU - Wilson,Mary E, AU - Freedman,David O, PY - 2007/9/1/pubmed PY - 2007/12/11/medline PY - 2007/9/1/entrez SP - 449 EP - 53 JF - Current opinion in infectious diseases JO - Curr. Opin. Infect. Dis. VL - 20 IS - 5 N2 - PURPOSE OF REVIEW: Many potentially life-threatening infections cause fever. Several recent large studies help to define causes of fever in returned travelers. RECENT FINDINGS: The destination of travel determines the relative likelihood of the different major causes of fever. Systemic febrile illness occurs disproportionately among ill travelers returning from sub-Saharan Africa. Malaria remains the most important overall cause of systemic febrile illness in travelers to tropical regions; dengue fever is now the most prominent cause of fever in travelers to certain regions, most notably Asia. Chikungunya fever has emerged as a major cause of fever in travelers to Indian Ocean islands off Africa and to India itself. Causes of fever vary by the time of presentation after travel. Vivax malaria is an important cause of fever with onset more than a month after return; recently studies have shown that parasites causing relapse are genetically distinct from those causing primary infection. At expert referral centers up to 25% of febrile patients have no specific cause of fever determined. SUMMARY: Knowledge of predominant causes of febrile infections by geographic region, traveler characteristics, and time of presentation can assist the clinician in guiding posttravel diagnosis and empiric therapy of ill returned travelers and is also valuable in pretravel preparation. SN - 0951-7375 UR - https://www.unboundmedicine.com/medline/citation/17762776/Etiology_of_travel_related_fever_ L2 - http://dx.doi.org/10.1097/QCO.0b013e3282a95e27 DB - PRIME DP - Unbound Medicine ER -