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Subtyping the irritable bowel syndrome by predominant bowel habit: Rome II versus Rome III.
Aliment Pharmacol Ther 2007; 26(6):953-61AP

Abstract

BACKGROUND

The agreement between subtyping irritable bowel syndrome (IBS) patients based on Rome II criteria versus Rome III criteria is unknown.

AIM

To compare IBS subtyping based on Rome II versus III criteria.

METHODS

The Rome II Modular Questionnaire and the Bristol Stool Form Scale (one-week diary cards) were completed by 249 IBS patients. Based on the Rome II criteria, patients were defined as having diarrhoea- or constipation-predominant IBS, or alternating IBS. Based on the Rome III criteria, patients were divided into IBS with constipation, IBS with diarrhoea, mixed IBS or unsubtyped IBS. Agreement between Rome II and Rome III was assessed with kappa statistics.

RESULTS

Based on Rome II there were 92 diarrhoea-predominant IBS, 45 constipation-predominant IBS and 112 alternating IBS, and based on Rome III 97 IBS with diarrhoea, 77 IBS with constipation, 16 mixed IBS and 59 unsubtyped IBS. The agreement between Rome II and Rome III subgroups was 46% (kappa = 0.19). Changes from the constipation to the diarrhoea subgroups and vice versa were uncommon (8% of patients). The majority of changes occurred from/to the alternating IBS, mixed IBS and unsubtyped IBS subgroups.

CONCLUSION

There is poor agreement between subtyping of IBS patients based on Rome II versus Rome III criteria.

Authors+Show Affiliations

Department of Internal Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17767480

Citation

Ersryd, A, et al. "Subtyping the Irritable Bowel Syndrome By Predominant Bowel Habit: Rome II Versus Rome III." Alimentary Pharmacology & Therapeutics, vol. 26, no. 6, 2007, pp. 953-61.
Ersryd A, Posserud I, Abrahamsson H, et al. Subtyping the irritable bowel syndrome by predominant bowel habit: Rome II versus Rome III. Aliment Pharmacol Ther. 2007;26(6):953-61.
Ersryd, A., Posserud, I., Abrahamsson, H., & Simrén, M. (2007). Subtyping the irritable bowel syndrome by predominant bowel habit: Rome II versus Rome III. Alimentary Pharmacology & Therapeutics, 26(6), pp. 953-61.
Ersryd A, et al. Subtyping the Irritable Bowel Syndrome By Predominant Bowel Habit: Rome II Versus Rome III. Aliment Pharmacol Ther. 2007 Sep 15;26(6):953-61. PubMed PMID: 17767480.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subtyping the irritable bowel syndrome by predominant bowel habit: Rome II versus Rome III. AU - Ersryd,A, AU - Posserud,I, AU - Abrahamsson,H, AU - Simrén,M, PY - 2007/9/5/pubmed PY - 2007/12/15/medline PY - 2007/9/5/entrez SP - 953 EP - 61 JF - Alimentary pharmacology & therapeutics JO - Aliment. Pharmacol. Ther. VL - 26 IS - 6 N2 - BACKGROUND: The agreement between subtyping irritable bowel syndrome (IBS) patients based on Rome II criteria versus Rome III criteria is unknown. AIM: To compare IBS subtyping based on Rome II versus III criteria. METHODS: The Rome II Modular Questionnaire and the Bristol Stool Form Scale (one-week diary cards) were completed by 249 IBS patients. Based on the Rome II criteria, patients were defined as having diarrhoea- or constipation-predominant IBS, or alternating IBS. Based on the Rome III criteria, patients were divided into IBS with constipation, IBS with diarrhoea, mixed IBS or unsubtyped IBS. Agreement between Rome II and Rome III was assessed with kappa statistics. RESULTS: Based on Rome II there were 92 diarrhoea-predominant IBS, 45 constipation-predominant IBS and 112 alternating IBS, and based on Rome III 97 IBS with diarrhoea, 77 IBS with constipation, 16 mixed IBS and 59 unsubtyped IBS. The agreement between Rome II and Rome III subgroups was 46% (kappa = 0.19). Changes from the constipation to the diarrhoea subgroups and vice versa were uncommon (8% of patients). The majority of changes occurred from/to the alternating IBS, mixed IBS and unsubtyped IBS subgroups. CONCLUSION: There is poor agreement between subtyping of IBS patients based on Rome II versus Rome III criteria. SN - 0269-2813 UR - https://www.unboundmedicine.com/medline/citation/17767480/Subtyping_the_irritable_bowel_syndrome_by_predominant_bowel_habit:_Rome_II_versus_Rome_III_ L2 - https://doi.org/10.1111/j.1365-2036.2007.03422.x DB - PRIME DP - Unbound Medicine ER -