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Mixed outbreak of Bordetella pertussis and Bordetella parapertussis in an apartment house.
Dev Biol Stand. 1991; 73:333-41.DB

Abstract

From September through November of 1985, a mixed outbreak of Bordetella pertussis and Bordetella parapertussis occurred in an apartment house in Ashikaga City, Japan. Bacteriological and serological investigations were conducted on seven families, comprising 13 adults and 19 children, living in the same apartment house and having social contacts. For all the subjects, cultivation of nasopharyngeal mucus and measurement of pertussis agglutinin antibody, anti-PT antibody, and anti-F-HA antibody were performed. On the basis of the clinical, bacteriological or serological findings, seven children of three families (families A, B and C), including the first child patient (index case) of family A, were diagnosed as having infections caused by B. pertussis, or B. parapertussis or both. B. pertussis and/or B. parapertussis were isolated from six of the seven child patients. B. pertussis alone was isolated from three children (one in each family), and two of them had not been vaccinated. B. parapertussis alone was isolated from two children, while both bacteria were isolated from one child. Those three children from whom B. parapertussis was isolated were in family C, which was the last of the three families to develop symptoms of infection. Josamycin had been administered to two of the three children from whom B. parapertussis was isolated before the nasopharyngeal mucus specimen was collected. In one of the two children from whom only B. parapertussis was isolated, the significant elevation of anti-PT antibody titer was observed, which was indicative of a mixed infection with B. pertussis.(ABSTRACT TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Department of Pediatrics, Kasumigaura National Hospital, Ibaraki, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1778328

Citation

Iwata, S, et al. "Mixed Outbreak of Bordetella Pertussis and Bordetella Parapertussis in an Apartment House." Developments in Biological Standardization, vol. 73, 1991, pp. 333-41.
Iwata S, Aoyama T, Goto A, et al. Mixed outbreak of Bordetella pertussis and Bordetella parapertussis in an apartment house. Dev Biol Stand. 1991;73:333-41.
Iwata, S., Aoyama, T., Goto, A., Iwai, H., Sato, Y., Akita, H., Murase, Y., Oikawa, T., Iwata, T., & Kusano, S. (1991). Mixed outbreak of Bordetella pertussis and Bordetella parapertussis in an apartment house. Developments in Biological Standardization, 73, 333-41.
Iwata S, et al. Mixed Outbreak of Bordetella Pertussis and Bordetella Parapertussis in an Apartment House. Dev Biol Stand. 1991;73:333-41. PubMed PMID: 1778328.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mixed outbreak of Bordetella pertussis and Bordetella parapertussis in an apartment house. A1 - Iwata,S, AU - Aoyama,T, AU - Goto,A, AU - Iwai,H, AU - Sato,Y, AU - Akita,H, AU - Murase,Y, AU - Oikawa,T, AU - Iwata,T, AU - Kusano,S, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 333 EP - 41 JF - Developments in biological standardization JO - Dev Biol Stand VL - 73 N2 - From September through November of 1985, a mixed outbreak of Bordetella pertussis and Bordetella parapertussis occurred in an apartment house in Ashikaga City, Japan. Bacteriological and serological investigations were conducted on seven families, comprising 13 adults and 19 children, living in the same apartment house and having social contacts. For all the subjects, cultivation of nasopharyngeal mucus and measurement of pertussis agglutinin antibody, anti-PT antibody, and anti-F-HA antibody were performed. On the basis of the clinical, bacteriological or serological findings, seven children of three families (families A, B and C), including the first child patient (index case) of family A, were diagnosed as having infections caused by B. pertussis, or B. parapertussis or both. B. pertussis and/or B. parapertussis were isolated from six of the seven child patients. B. pertussis alone was isolated from three children (one in each family), and two of them had not been vaccinated. B. parapertussis alone was isolated from two children, while both bacteria were isolated from one child. Those three children from whom B. parapertussis was isolated were in family C, which was the last of the three families to develop symptoms of infection. Josamycin had been administered to two of the three children from whom B. parapertussis was isolated before the nasopharyngeal mucus specimen was collected. In one of the two children from whom only B. parapertussis was isolated, the significant elevation of anti-PT antibody titer was observed, which was indicative of a mixed infection with B. pertussis.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0301-5149 UR - https://www.unboundmedicine.com/medline/citation/1778328/Mixed_outbreak_of_Bordetella_pertussis_and_Bordetella_parapertussis_in_an_apartment_house_ L2 - https://medlineplus.gov/whoopingcough.html DB - PRIME DP - Unbound Medicine ER -