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[Impact of drug-eluting stents on transferring treatment with coronary surgical revascularization among patients initially admitted to department of internal medicine].
Zhonghua Yi Xue Za Zhi. 2007 Jun 12; 87(22):1518-22.ZY

Abstract

OBJECTIVE

To evaluate the impact of drug-eluting stent (DES) on transferring treatment with coronary surgical revascularization among the patients initially admitted to department of internal medicine.

METHODS

2598 patients initially admitted in department of internal medicine underwent revascularization by percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) before the introduction of DES from 1 July 2001 to 30 June 2002 [bare metal stent (BMS) era group, n = 923) or after the introduction of DES from 1 July 2003 to 30 June 2004 (DES era group). The clinical manifestations and coronary angiography characteristics were analyzed retrospectively.

RESULTS

In the DES era group 1333 patients (80.1%) were revascularized with PCI, and 331 patients (19.9%) were transferred to treatment with CABG; and in the BMS era group, 721 patients (77.2%) underwent PCI, and 213 patients (22.8%) were transferred to treatment with CABG. The rate of transference to CABG of the DES era group was lower by 12.7% compared with the BMS era group. The rates of left main coronary disease, proximal left anterior descending coronary stenosis and diffuse long lesions among the patients revascularized with PCI in the DES era group were 3.2%, 44.2%, and 19.7% respectively, all significantly higher than those in the BMS era group (1.4%, 39.8%, and 11.2%, P = 0.025, P = 0.047, and = 0.021 respectively). But no matter if DES was implanted or not, left main coronary disease, proximal left anterior descending coronary stenosis, diffuse long lesions and ostial lesions were the most common coronary lesions in the patients revascularized with CABG. Logistic regression showed that number of diseased vessels, left main coronary disease, chronic total occlusion lesions, and proximal left anterior descending coronary stenosis were independent predictor for transferring treatment with CABG (all P < 0.0001).

CONCLUSION

DES has a certain impact on the coronary revascularization strategies, because the rate of in-stent restenosis and repeat revascularization are lower significantly after implantation of DES than after implantation of BMS. Many coronary lesions that should undergo CABG in non-DES era may be revascularized with PCI and implantation of DES.

Authors+Show Affiliations

Department of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

17785099

Citation

He, Li-qun, et al. "[Impact of Drug-eluting Stents On Transferring Treatment With Coronary Surgical Revascularization Among Patients Initially Admitted to Department of Internal Medicine]." Zhonghua Yi Xue Za Zhi, vol. 87, no. 22, 2007, pp. 1518-22.
He LQ, Ma CS, Nie SP, et al. [Impact of drug-eluting stents on transferring treatment with coronary surgical revascularization among patients initially admitted to department of internal medicine]. Zhonghua Yi Xue Za Zhi. 2007;87(22):1518-22.
He, L. Q., Ma, C. S., Nie, S. P., Lü, Q., Jia, C. Q., DU, X., Liu, X. H., Dong, J. Z., Li, Z. Z., Chen, F., Zhou, Y. J., Lü, S. Z., & Wu, X. S. (2007). [Impact of drug-eluting stents on transferring treatment with coronary surgical revascularization among patients initially admitted to department of internal medicine]. Zhonghua Yi Xue Za Zhi, 87(22), 1518-22.
He LQ, et al. [Impact of Drug-eluting Stents On Transferring Treatment With Coronary Surgical Revascularization Among Patients Initially Admitted to Department of Internal Medicine]. Zhonghua Yi Xue Za Zhi. 2007 Jun 12;87(22):1518-22. PubMed PMID: 17785099.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Impact of drug-eluting stents on transferring treatment with coronary surgical revascularization among patients initially admitted to department of internal medicine]. AU - He,Li-qun, AU - Ma,Chang-sheng, AU - Nie,Shao-ping, AU - Lü,Qiang, AU - Jia,Chang-qi, AU - DU,Xin, AU - Liu,Xiao-hui, AU - Dong,Jian-zeng, AU - Li,Zhi-zhong, AU - Chen,Fang, AU - Zhou,Yu-jie, AU - Lü,Shu-zheng, AU - Wu,Xue-si, PY - 2007/9/6/pubmed PY - 2008/11/1/medline PY - 2007/9/6/entrez SP - 1518 EP - 22 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 87 IS - 22 N2 - OBJECTIVE: To evaluate the impact of drug-eluting stent (DES) on transferring treatment with coronary surgical revascularization among the patients initially admitted to department of internal medicine. METHODS: 2598 patients initially admitted in department of internal medicine underwent revascularization by percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) before the introduction of DES from 1 July 2001 to 30 June 2002 [bare metal stent (BMS) era group, n = 923) or after the introduction of DES from 1 July 2003 to 30 June 2004 (DES era group). The clinical manifestations and coronary angiography characteristics were analyzed retrospectively. RESULTS: In the DES era group 1333 patients (80.1%) were revascularized with PCI, and 331 patients (19.9%) were transferred to treatment with CABG; and in the BMS era group, 721 patients (77.2%) underwent PCI, and 213 patients (22.8%) were transferred to treatment with CABG. The rate of transference to CABG of the DES era group was lower by 12.7% compared with the BMS era group. The rates of left main coronary disease, proximal left anterior descending coronary stenosis and diffuse long lesions among the patients revascularized with PCI in the DES era group were 3.2%, 44.2%, and 19.7% respectively, all significantly higher than those in the BMS era group (1.4%, 39.8%, and 11.2%, P = 0.025, P = 0.047, and = 0.021 respectively). But no matter if DES was implanted or not, left main coronary disease, proximal left anterior descending coronary stenosis, diffuse long lesions and ostial lesions were the most common coronary lesions in the patients revascularized with CABG. Logistic regression showed that number of diseased vessels, left main coronary disease, chronic total occlusion lesions, and proximal left anterior descending coronary stenosis were independent predictor for transferring treatment with CABG (all P < 0.0001). CONCLUSION: DES has a certain impact on the coronary revascularization strategies, because the rate of in-stent restenosis and repeat revascularization are lower significantly after implantation of DES than after implantation of BMS. Many coronary lesions that should undergo CABG in non-DES era may be revascularized with PCI and implantation of DES. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/17785099/[Impact_of_drug_eluting_stents_on_transferring_treatment_with_coronary_surgical_revascularization_among_patients_initially_admitted_to_department_of_internal_medicine]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0376-2491&amp;year=2007&amp;vol=87&amp;issue=22&amp;fpage=1518 DB - PRIME DP - Unbound Medicine ER -