TY - JOUR T1 - MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. AU - van Rooij,Eva, AU - Olson,Eric N, PY - 2007/9/6/pubmed PY - 2007/10/24/medline PY - 2007/9/6/entrez SP - 2369 EP - 76 JF - The Journal of clinical investigation JO - J Clin Invest VL - 117 IS - 9 N2 - MicroRNAs act as negative regulators of gene expression by inhibiting the translation or promoting the degradation of target mRNAs. Recent studies have revealed key roles of microRNAs as regulators of the growth, development, function, and stress responsiveness of the heart, providing glimpses of undiscovered regulatory mechanisms and potential therapeutic targets for the treatment of heart disease. SN - 0021-9738 UR - https://www.unboundmedicine.com/medline/citation/17786230/MicroRNAs:_powerful_new_regulators_of_heart_disease_and_provocative_therapeutic_targets_ L2 - https://doi.org/10.1172/JCI33099 DB - PRIME DP - Unbound Medicine ER -