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[Effect of concentration of catalpol and 5-hydroxymethyl-2-furaldehyde from processing of Rehmanniae Radix].
Zhongguo Zhong Yao Za Zhi. 2007 Jun; 32(12):1155-7.ZZ

Abstract

OBJECTIVE

To study on effect of concentration of catalpol and 5-hydroxy methyl-2-furaldehyde (5-HMF) from Rehmanniae Radix at various processing.

METHOD

The Rehmanniae Radix was dried and prepared from the steaming process with 10% ethanol, 50% ethanol at 90 degrees C and 100 degrees C each other. And the changes of catalpol and 5-HMF was determinated. The extraction of 5-HMF and catalpol was sonicated in 30% methanol for 2 h. The analysis of 5-HMF and catalpol was conducted by HPLC with reversed-phase C-18 column and detected under UV 284 nm, 204 nm. Elution was carried out at 1.0 mL min(-1) with 3% acetonitrile.

RESULT

From this analysis, we found out that the content of catalpol was decreased with the number of processing times, and content of 5-HMF was increased with the number of processing times at various processing. The temperature and concentration of ethanol can effect on content of catalpol and 5-HMF at processing. The Cooked Rehmanniae Radix processed at 100 degrees C, 10% ethanol is best. And the content of 5-HMF processed for more than 7 times was accorded with standard of Korea phamcopoetia.

CONCLUSION

Analyze the effect of concentration of catalpol and 5-HMF from Rehmanniae Radix at various processing, and provide the foundation for further study.

Authors+Show Affiliations

Department of Oriental Pharmaceutical Sciences, College of Phamacy, Kyung Hee University, Seoul 130701, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

17802874

Citation

Zhu, Mei-fen, et al. "[Effect of Concentration of Catalpol and 5-hydroxymethyl-2-furaldehyde From Processing of Rehmanniae Radix]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 32, no. 12, 2007, pp. 1155-7.
Zhu MF, Liu XQ, Ju-hee O, et al. [Effect of concentration of catalpol and 5-hydroxymethyl-2-furaldehyde from processing of Rehmanniae Radix]. Zhongguo Zhong Yao Za Zhi. 2007;32(12):1155-7.
Zhu, M. F., Liu, X. Q., Ju-hee, O., Chang-soo, Y., & Je-Hyun, L. (2007). [Effect of concentration of catalpol and 5-hydroxymethyl-2-furaldehyde from processing of Rehmanniae Radix]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 32(12), 1155-7.
Zhu MF, et al. [Effect of Concentration of Catalpol and 5-hydroxymethyl-2-furaldehyde From Processing of Rehmanniae Radix]. Zhongguo Zhong Yao Za Zhi. 2007;32(12):1155-7. PubMed PMID: 17802874.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effect of concentration of catalpol and 5-hydroxymethyl-2-furaldehyde from processing of Rehmanniae Radix]. AU - Zhu,Mei-fen, AU - Liu,Xiang-qian, AU - Ju-hee,Oh, AU - Chang-soo,Yook, AU - Je-Hyun,Lee, PY - 2007/9/7/pubmed PY - 2008/10/7/medline PY - 2007/9/7/entrez SP - 1155 EP - 7 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 32 IS - 12 N2 - OBJECTIVE: To study on effect of concentration of catalpol and 5-hydroxy methyl-2-furaldehyde (5-HMF) from Rehmanniae Radix at various processing. METHOD: The Rehmanniae Radix was dried and prepared from the steaming process with 10% ethanol, 50% ethanol at 90 degrees C and 100 degrees C each other. And the changes of catalpol and 5-HMF was determinated. The extraction of 5-HMF and catalpol was sonicated in 30% methanol for 2 h. The analysis of 5-HMF and catalpol was conducted by HPLC with reversed-phase C-18 column and detected under UV 284 nm, 204 nm. Elution was carried out at 1.0 mL min(-1) with 3% acetonitrile. RESULT: From this analysis, we found out that the content of catalpol was decreased with the number of processing times, and content of 5-HMF was increased with the number of processing times at various processing. The temperature and concentration of ethanol can effect on content of catalpol and 5-HMF at processing. The Cooked Rehmanniae Radix processed at 100 degrees C, 10% ethanol is best. And the content of 5-HMF processed for more than 7 times was accorded with standard of Korea phamcopoetia. CONCLUSION: Analyze the effect of concentration of catalpol and 5-HMF from Rehmanniae Radix at various processing, and provide the foundation for further study. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/17802874/[Effect_of_concentration_of_catalpol_and_5_hydroxymethyl_2_furaldehyde_from_processing_of_Rehmanniae_Radix]_ DB - PRIME DP - Unbound Medicine ER -