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Serum magnesium: an early predictor of course and complications of diabetes mellitus.

Abstract

The aim of this study was to evaluate relationship between serum magnesium and course of diabetes mellitus and also to find out, if there is any relation between serum magnesium and various complications of diabetes mellitus. A cross-sectional study was conducted to examine the relationship between serum magnesium in 50 type 1 and type 2 diabetic patients with or without complications and 40 normal healthy persons. Serum magneisum estimation was done using calmagite dye method using autoanalyser (Beckman DU clin systems). Serum magnesium levels in diabetic population was significantly low (1.93 +/- 0.282 meq/l) in comparison to control (2.25 +/- 0.429 meq/l). It was statistically significant (+3.84; p < 0.005). Serum magnesium was significantly low in diabetes with complication than without complications (p < 0.001). Duration of diabetes and serum magnesium were inversely related. Poor glycaemic control was associated with hypomagnesaemia (-2.623; p < 0.05). There was strong association between hypomagnesaemia and retinopathy (1.76 +/- 0.26), obesity (1.878 +/- 0.326) and hypertension (1.75 +/- 0.071) and it was statistically significantly (p < 0.005, 0.042, 0.000 respectively). Hence it is concluded that the change in serum magnesium level may have a bearing on the complication and morbidity in patients of diabetes mellitus.

Authors+Show Affiliations

,

Department of Medicine, SP Medical College, Bikaner 334003.

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Source

Journal of the Indian Medical Association 105:1 2007 Jan pg 16, 18, 20

MeSH

Adult
Biomarkers
Case-Control Studies
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Diabetic Retinopathy
Glycated Hemoglobin A
Humans
Indicators and Reagents
Magnesium
Magnesium Deficiency
Middle Aged

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17802971

Citation

Sharma, Aradhana, et al. "Serum Magnesium: an Early Predictor of Course and Complications of Diabetes Mellitus." Journal of the Indian Medical Association, vol. 105, no. 1, 2007, pp. 16, 18, 20.
Sharma A, Dabla S, Agrawal RP, et al. Serum magnesium: an early predictor of course and complications of diabetes mellitus. J Indian Med Assoc. 2007;105(1):16, 18, 20.
Sharma, A., Dabla, S., Agrawal, R. P., Barjatya, H., Kochar, D. K., & Kothari, R. P. (2007). Serum magnesium: an early predictor of course and complications of diabetes mellitus. Journal of the Indian Medical Association, 105(1), pp. 16, 18, 20.
Sharma A, et al. Serum Magnesium: an Early Predictor of Course and Complications of Diabetes Mellitus. J Indian Med Assoc. 2007;105(1):16, 18, 20. PubMed PMID: 17802971.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum magnesium: an early predictor of course and complications of diabetes mellitus. AU - Sharma,Aradhana, AU - Dabla,Surekha, AU - Agrawal,R P, AU - Barjatya,H, AU - Kochar,D K, AU - Kothari,R P, PY - 2007/9/7/pubmed PY - 2007/12/13/medline PY - 2007/9/7/entrez SP - 16, 18, 20 JF - Journal of the Indian Medical Association JO - J Indian Med Assoc VL - 105 IS - 1 N2 - The aim of this study was to evaluate relationship between serum magnesium and course of diabetes mellitus and also to find out, if there is any relation between serum magnesium and various complications of diabetes mellitus. A cross-sectional study was conducted to examine the relationship between serum magnesium in 50 type 1 and type 2 diabetic patients with or without complications and 40 normal healthy persons. Serum magneisum estimation was done using calmagite dye method using autoanalyser (Beckman DU clin systems). Serum magnesium levels in diabetic population was significantly low (1.93 +/- 0.282 meq/l) in comparison to control (2.25 +/- 0.429 meq/l). It was statistically significant (+3.84; p < 0.005). Serum magnesium was significantly low in diabetes with complication than without complications (p < 0.001). Duration of diabetes and serum magnesium were inversely related. Poor glycaemic control was associated with hypomagnesaemia (-2.623; p < 0.05). There was strong association between hypomagnesaemia and retinopathy (1.76 +/- 0.26), obesity (1.878 +/- 0.326) and hypertension (1.75 +/- 0.071) and it was statistically significantly (p < 0.005, 0.042, 0.000 respectively). Hence it is concluded that the change in serum magnesium level may have a bearing on the complication and morbidity in patients of diabetes mellitus. SN - 0019-5847 UR - https://www.unboundmedicine.com/medline/citation/17802971/Serum_magnesium:_an_early_predictor_of_course_and_complications_of_diabetes_mellitus_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -