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Comparison of sleep variables between chronic widespread musculoskeletal pain, insomnia, periodic leg movements syndrome and control subjects in a clinical sleep medicine practice.
Sleep Med. 2008 May; 9(4):352-61.SM

Abstract

BACKGROUND

Between 50% and 89% of chronic pain patients report unrefreshing sleep. The aim of this retrospective analysis was to compare the sleep of normal subjects with the sleep of a clinical population presenting musculoskeletal chronic widespread pain (CWP), psychophysiological insomnia and restless legs syndrome/periodic limb movements during sleep (RLS/PLMS) in order to identify sleep variables that may explain the poor sleep complaints of CWP patients.

METHODS

Sleep data from 10 normal subjects and 37 patients (mean age 55+/-3 yo), matched for age and sex, were retrieved from our sleep data bank. Sub-analysis controlled for the effects of medication.

RESULTS

In comparison to normal subjects, sleep duration was shorter in CWP patients (-71 min; p<0.01); sleep efficiency was significantly lower in CWP and insomnia patients (-10.1% and -11.1%, respectively; p<0.05). CWP and PLMS patients lost one non-rapid eye movement (REM) to REM sleep cycle (p<0.04). An intermediate level of PLM was observed during the sleep of CWP patients in comparison to normal subjects (8.8/h vs. 2.0/h) and PLMS patients (33/h). Regular use of non-narcotic analgesics did not seem to interfere with sleep variables.

CONCLUSIONS

The sleep of middle-aged patients with CWP is comparable to that of insomnia patients. The moderate level of PLM during sleep suggests that such sensory motor activity needs to be evaluated in patients suffering from chronic pain.

Authors+Show Affiliations

Facultés de médecine dentaire et de médecine, Université de Montréal, CP 6128, succursale Centre-ville, Montréal, Que., Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17804292

Citation

Okura, Kazuo, et al. "Comparison of Sleep Variables Between Chronic Widespread Musculoskeletal Pain, Insomnia, Periodic Leg Movements Syndrome and Control Subjects in a Clinical Sleep Medicine Practice." Sleep Medicine, vol. 9, no. 4, 2008, pp. 352-61.
Okura K, Lavigne GJ, Huynh N, et al. Comparison of sleep variables between chronic widespread musculoskeletal pain, insomnia, periodic leg movements syndrome and control subjects in a clinical sleep medicine practice. Sleep Med. 2008;9(4):352-61.
Okura, K., Lavigne, G. J., Huynh, N., Manzini, C., Fillipini, D., & Montplaisir, J. Y. (2008). Comparison of sleep variables between chronic widespread musculoskeletal pain, insomnia, periodic leg movements syndrome and control subjects in a clinical sleep medicine practice. Sleep Medicine, 9(4), 352-61.
Okura K, et al. Comparison of Sleep Variables Between Chronic Widespread Musculoskeletal Pain, Insomnia, Periodic Leg Movements Syndrome and Control Subjects in a Clinical Sleep Medicine Practice. Sleep Med. 2008;9(4):352-61. PubMed PMID: 17804292.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of sleep variables between chronic widespread musculoskeletal pain, insomnia, periodic leg movements syndrome and control subjects in a clinical sleep medicine practice. AU - Okura,Kazuo, AU - Lavigne,Gilles J, AU - Huynh,Nelly, AU - Manzini,Christiane, AU - Fillipini,Daniel, AU - Montplaisir,Jacques Y, Y1 - 2007/09/04/ PY - 2006/10/10/received PY - 2007/07/03/revised PY - 2007/07/12/accepted PY - 2007/9/7/pubmed PY - 2008/12/17/medline PY - 2007/9/7/entrez SP - 352 EP - 61 JF - Sleep medicine JO - Sleep Med VL - 9 IS - 4 N2 - BACKGROUND: Between 50% and 89% of chronic pain patients report unrefreshing sleep. The aim of this retrospective analysis was to compare the sleep of normal subjects with the sleep of a clinical population presenting musculoskeletal chronic widespread pain (CWP), psychophysiological insomnia and restless legs syndrome/periodic limb movements during sleep (RLS/PLMS) in order to identify sleep variables that may explain the poor sleep complaints of CWP patients. METHODS: Sleep data from 10 normal subjects and 37 patients (mean age 55+/-3 yo), matched for age and sex, were retrieved from our sleep data bank. Sub-analysis controlled for the effects of medication. RESULTS: In comparison to normal subjects, sleep duration was shorter in CWP patients (-71 min; p<0.01); sleep efficiency was significantly lower in CWP and insomnia patients (-10.1% and -11.1%, respectively; p<0.05). CWP and PLMS patients lost one non-rapid eye movement (REM) to REM sleep cycle (p<0.04). An intermediate level of PLM was observed during the sleep of CWP patients in comparison to normal subjects (8.8/h vs. 2.0/h) and PLMS patients (33/h). Regular use of non-narcotic analgesics did not seem to interfere with sleep variables. CONCLUSIONS: The sleep of middle-aged patients with CWP is comparable to that of insomnia patients. The moderate level of PLM during sleep suggests that such sensory motor activity needs to be evaluated in patients suffering from chronic pain. SN - 1389-9457 UR - https://www.unboundmedicine.com/medline/citation/17804292/Comparison_of_sleep_variables_between_chronic_widespread_musculoskeletal_pain_insomnia_periodic_leg_movements_syndrome_and_control_subjects_in_a_clinical_sleep_medicine_practice_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1389-9457(07)00263-8 DB - PRIME DP - Unbound Medicine ER -