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[Endocrine response to extracorporeal circulation].

Abstract

The authors analyze the results of measuring the content of vasopressin, renin, angiotensin II and aldosterone coupled with the results of studying hemodynamics, acid-base state, and lactate in the arterial blood during operations on the heart in 32 patients with different acquired heart diseases. The main attention was concentrated on studies into the nature of humoral changes during extracorporeal circulation in three types of anesthesia. In group I, anesthesia was maintained by fentanyl given in a dose of 5-6 micrograms/kg/h, diazepam (0.1 mg/kg/h), and arduan (0.02 mg/kg/h). In the second observation group, at the beginning of perfusion the patients were administered trimetotan (artonad) (0.2 mg/kg), and in group III, the dose of fentanyl was raised during perfusion to 10-12 micrograms/kg/h. It is concluded that during extracorporeal circulation, it is desirable that the dose of fentanyl be increased to attain more adequate anesthesia in that period of heart surgery. The magnitude of humoral changes occurring in the body during extracorporeal circulation served as a criterion for anesthesia adequacy.

Authors

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Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

1781213

Citation

Meshcheriakov, A V., et al. "[Endocrine Response to Extracorporeal Circulation]." Vestnik Akademii Meditsinskikh Nauk SSSR, 1991, pp. 21-4.
Meshcheriakov AV, Nurmatov UB, Vinnitskiĭ LI, et al. [Endocrine response to extracorporeal circulation]. Vestn Akad Med Nauk SSSR. 1991.
Meshcheriakov, A. V., Nurmatov, U. B., Vinnitskiĭ, L. I., Dement'eva, I. I., & Egorova, I. A. (1991). [Endocrine response to extracorporeal circulation]. Vestnik Akademii Meditsinskikh Nauk SSSR, (7), 21-4.
Meshcheriakov AV, et al. [Endocrine Response to Extracorporeal Circulation]. Vestn Akad Med Nauk SSSR. 1991;(7)21-4. PubMed PMID: 1781213.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Endocrine response to extracorporeal circulation]. AU - Meshcheriakov,A V, AU - Nurmatov,U B, AU - Vinnitskiĭ,L I, AU - Dement'eva,I I, AU - Egorova,I A, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 21 EP - 4 JF - Vestnik Akademii meditsinskikh nauk SSSR JO - Vestn Akad Med Nauk SSSR IS - 7 N2 - The authors analyze the results of measuring the content of vasopressin, renin, angiotensin II and aldosterone coupled with the results of studying hemodynamics, acid-base state, and lactate in the arterial blood during operations on the heart in 32 patients with different acquired heart diseases. The main attention was concentrated on studies into the nature of humoral changes during extracorporeal circulation in three types of anesthesia. In group I, anesthesia was maintained by fentanyl given in a dose of 5-6 micrograms/kg/h, diazepam (0.1 mg/kg/h), and arduan (0.02 mg/kg/h). In the second observation group, at the beginning of perfusion the patients were administered trimetotan (artonad) (0.2 mg/kg), and in group III, the dose of fentanyl was raised during perfusion to 10-12 micrograms/kg/h. It is concluded that during extracorporeal circulation, it is desirable that the dose of fentanyl be increased to attain more adequate anesthesia in that period of heart surgery. The magnitude of humoral changes occurring in the body during extracorporeal circulation served as a criterion for anesthesia adequacy. SN - 0002-3027 UR - https://www.unboundmedicine.com/medline/citation/1781213/[Endocrine_response_to_extracorporeal_circulation]_ L2 - https://medlineplus.gov/heartdiseases.html DB - PRIME DP - Unbound Medicine ER -