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The benign prostatic hyperplasia registry and patient survey: study design, methods and patient baseline characteristics.
BJU Int. 2007 Oct; 100(4):813-9.BI

Abstract

OBJECTIVE

To describe the design and baseline cohort characteristics of the Benign Prostatic Hyperplasia (BPH) Registry and Patient Survey, an ongoing, prospective, observational, disease registry documenting management practices and patient outcomes in men in the USA with lower urinary tract symptoms associated with BPH (LUTS/BPH) in actual clinical practice settings.

PATIENTS AND METHODS

Men with LUTS/BPH who were either untreated or treated with alpha(1)-adrenergic blockers (ABs), 5alpha-reductase inhibitors (5ARIs), a combination of these medications, or anticholinergics, and who met selection criteria, were enrolled at sites throughout the USA. At each visit, standardized forms and validated questionnaires were completed to assess the physicians' management practices and patients' clinical characteristics, sexual function, and health-related quality of life.

RESULTS

At the close of recruitment (February 2005), 6909 men (mean age 66.0 years) were enrolled at 402 sites by urologists and primary-care physicians. Before enrolment, 49% of the men were managed with watchful waiting (WW), 21% with uroselective AB monotherapy, 11% with non-uroselective AB monotherapy, 6% with 5ARI monotherapy, 11% with AB + 5ARI, and 2% with anticholinergics. After enrolment, 42% were on WW and 26% were on selective AB monotherapy; changes in other management groups were minimal. Overall, 33% of the men had mild, 52% had moderate and 15% had severe LUTS. The most common comorbidities were hypertension (53%), high cholesterol (45%) and sexual dysfunction (36%).

CONCLUSION

The BPH Registry and Patient Survey will provide information on physician management practices and outcomes of men with LUTS/BPH, while examining the effects of demographics, socio-economics, comorbidities, and medical therapies.

Authors+Show Affiliations

Department of Urology, The University of Texas South-Western Medical Center, Dallas, Texas, USA. claus.roerborn@utsouthwestern.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

17822462

Citation

Roehrborn, Claus G., et al. "The Benign Prostatic Hyperplasia Registry and Patient Survey: Study Design, Methods and Patient Baseline Characteristics." BJU International, vol. 100, no. 4, 2007, pp. 813-9.
Roehrborn CG, Nuckolls JG, Wei JT, et al. The benign prostatic hyperplasia registry and patient survey: study design, methods and patient baseline characteristics. BJU Int. 2007;100(4):813-9.
Roehrborn, C. G., Nuckolls, J. G., Wei, J. T., & Steers, W. (2007). The benign prostatic hyperplasia registry and patient survey: study design, methods and patient baseline characteristics. BJU International, 100(4), 813-9.
Roehrborn CG, et al. The Benign Prostatic Hyperplasia Registry and Patient Survey: Study Design, Methods and Patient Baseline Characteristics. BJU Int. 2007;100(4):813-9. PubMed PMID: 17822462.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The benign prostatic hyperplasia registry and patient survey: study design, methods and patient baseline characteristics. AU - Roehrborn,Claus G, AU - Nuckolls,James G, AU - Wei,John T, AU - Steers,William, AU - ,, PY - 2007/9/8/pubmed PY - 2007/12/6/medline PY - 2007/9/8/entrez SP - 813 EP - 9 JF - BJU international JO - BJU Int VL - 100 IS - 4 N2 - OBJECTIVE: To describe the design and baseline cohort characteristics of the Benign Prostatic Hyperplasia (BPH) Registry and Patient Survey, an ongoing, prospective, observational, disease registry documenting management practices and patient outcomes in men in the USA with lower urinary tract symptoms associated with BPH (LUTS/BPH) in actual clinical practice settings. PATIENTS AND METHODS: Men with LUTS/BPH who were either untreated or treated with alpha(1)-adrenergic blockers (ABs), 5alpha-reductase inhibitors (5ARIs), a combination of these medications, or anticholinergics, and who met selection criteria, were enrolled at sites throughout the USA. At each visit, standardized forms and validated questionnaires were completed to assess the physicians' management practices and patients' clinical characteristics, sexual function, and health-related quality of life. RESULTS: At the close of recruitment (February 2005), 6909 men (mean age 66.0 years) were enrolled at 402 sites by urologists and primary-care physicians. Before enrolment, 49% of the men were managed with watchful waiting (WW), 21% with uroselective AB monotherapy, 11% with non-uroselective AB monotherapy, 6% with 5ARI monotherapy, 11% with AB + 5ARI, and 2% with anticholinergics. After enrolment, 42% were on WW and 26% were on selective AB monotherapy; changes in other management groups were minimal. Overall, 33% of the men had mild, 52% had moderate and 15% had severe LUTS. The most common comorbidities were hypertension (53%), high cholesterol (45%) and sexual dysfunction (36%). CONCLUSION: The BPH Registry and Patient Survey will provide information on physician management practices and outcomes of men with LUTS/BPH, while examining the effects of demographics, socio-economics, comorbidities, and medical therapies. SN - 1464-4096 UR - https://www.unboundmedicine.com/medline/citation/17822462/The_benign_prostatic_hyperplasia_registry_and_patient_survey:_study_design_methods_and_patient_baseline_characteristics_ L2 - https://doi.org/10.1111/j.1464-410X.2007.07061.x DB - PRIME DP - Unbound Medicine ER -