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The long term (5-years) objective TVT success rate does not depend on predictive factors at multivariate analysis: a multicentre retrospective study.
Eur Urol. 2008 Jan; 53(1):176-82.EU

Abstract

OBJECTIVES

We evaluated the predictive risk factors that could affect the long-term efficacy of the tension-free vaginal tape (TVT) procedure for the treatment of female stress urinary incontinence (SUI).

METHODS

One hundred thirty-eight (mean age, 52.4+/-9.3 yr) women who underwent the TVT procedure for SUI were selected and followed up for at least 5 yr (mean, 67.2 mo; range, 60-76) after the surgery. We analyzed the preoperative and intraoperative parameters using univariate and multivariate regression for cure rates and patients' satisfaction.

RESULTS

The overall 5-yr cure rate was 76.8%, with a satisfaction rate of 86.9%. The cure rates were lower in patients with high body mass index (BMI>or=25 kg/m2/BMI<25 kg/m2=68.3%:83.3%, p=0.044), low abdominal leak point pressure (ALPP<60 cm H2O/ALPP>or=60 cm H2O=51.6%:82.8%, p=0.003), and high grade of SUI (40.0% in grade III; 69.7% in grade II; 86.6% in grade I, p=0.012). On multivariate analysis, there were no independent risk factors related to cure rate, and urgency was the only factor independently associated with patients' satisfaction (p=0.017; odds ratio=4.114).

CONCLUSIONS

This study demonstrates that the TVT procedure is effective for female SUI without any independent predictive factors affecting long-term cure rate. Urgency was the only predictive factor affecting patient satisfaction. However, high BMI, low ALPP, and high grade of incontinence may impair the cure rate of the TVT.

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Authors+Show Affiliations

Lee KS
Department Of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Choo MS
No affiliation info available
Doo CK
No affiliation info available
Han DH
No affiliation info available
Lee YS
No affiliation info available
Kim JY
No affiliation info available
Kim WS
No affiliation info available
Jung HC
No affiliation info available

MeSH

AdultAgedBody Mass IndexFemaleFollow-Up StudiesHumansMiddle AgedMultivariate AnalysisPatient SatisfactionPredictive Value of TestsProsthesis ImplantationRetrospective StudiesRheologyRisk FactorsSuburethral SlingsTime FactorsTreatment OutcomeUrinary Incontinence, StressUrodynamicsUrologic Surgical Procedures

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

17825478

Citation

Lee, Kyu-Sung, et al. "The Long Term (5-years) Objective TVT Success Rate Does Not Depend On Predictive Factors at Multivariate Analysis: a Multicentre Retrospective Study." European Urology, vol. 53, no. 1, 2008, pp. 176-82.
Lee KS, Choo MS, Doo CK, et al. The long term (5-years) objective TVT success rate does not depend on predictive factors at multivariate analysis: a multicentre retrospective study. Eur Urol. 2008;53(1):176-82.
Lee, K. S., Choo, M. S., Doo, C. K., Han, D. H., Lee, Y. S., Kim, J. Y., Kim, W. S., & Jung, H. C. (2008). The long term (5-years) objective TVT success rate does not depend on predictive factors at multivariate analysis: a multicentre retrospective study. European Urology, 53(1), 176-82.
Lee KS, et al. The Long Term (5-years) Objective TVT Success Rate Does Not Depend On Predictive Factors at Multivariate Analysis: a Multicentre Retrospective Study. Eur Urol. 2008;53(1):176-82. PubMed PMID: 17825478.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The long term (5-years) objective TVT success rate does not depend on predictive factors at multivariate analysis: a multicentre retrospective study. AU - Lee,Kyu-Sung, AU - Choo,Myung-Soo, AU - Doo,Chin Kyung, AU - Han,Deok-Hyun, AU - Lee,Young-Suk, AU - Kim,Ji Yoon, AU - Kim,Wan Suk, AU - Jung,Hee Chang, Y1 - 2007/08/28/ PY - 2007/04/23/received PY - 2007/08/17/accepted PY - 2007/9/11/pubmed PY - 2008/3/12/medline PY - 2007/9/11/entrez SP - 176 EP - 82 JF - European urology JO - Eur Urol VL - 53 IS - 1 N2 - OBJECTIVES: We evaluated the predictive risk factors that could affect the long-term efficacy of the tension-free vaginal tape (TVT) procedure for the treatment of female stress urinary incontinence (SUI). METHODS: One hundred thirty-eight (mean age, 52.4+/-9.3 yr) women who underwent the TVT procedure for SUI were selected and followed up for at least 5 yr (mean, 67.2 mo; range, 60-76) after the surgery. We analyzed the preoperative and intraoperative parameters using univariate and multivariate regression for cure rates and patients' satisfaction. RESULTS: The overall 5-yr cure rate was 76.8%, with a satisfaction rate of 86.9%. The cure rates were lower in patients with high body mass index (BMI>or=25 kg/m2/BMI<25 kg/m2=68.3%:83.3%, p=0.044), low abdominal leak point pressure (ALPP<60 cm H2O/ALPP>or=60 cm H2O=51.6%:82.8%, p=0.003), and high grade of SUI (40.0% in grade III; 69.7% in grade II; 86.6% in grade I, p=0.012). On multivariate analysis, there were no independent risk factors related to cure rate, and urgency was the only factor independently associated with patients' satisfaction (p=0.017; odds ratio=4.114). CONCLUSIONS: This study demonstrates that the TVT procedure is effective for female SUI without any independent predictive factors affecting long-term cure rate. Urgency was the only predictive factor affecting patient satisfaction. However, high BMI, low ALPP, and high grade of incontinence may impair the cure rate of the TVT. SN - 0302-2838 UR - https://www.unboundmedicine.com/medline/citation/17825478/The_long_term__5_years__objective_TVT_success_rate_does_not_depend_on_predictive_factors_at_multivariate_analysis:_a_multicentre_retrospective_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0302-2838(07)01092-5 DB - PRIME DP - Unbound Medicine ER -
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