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The likelihood of diabetes based on the proposed definitions for impaired fasting glucose.
Diabetes Res Clin Pract. 2008 Jan; 79(1):151-5.DR

Abstract

The current study aimed to evaluate whether individuals with fasting plasma glucose (FPG) of 5.6-6.0 mmol/l has a similar risk profiles for diabetes or impaired glucose tolerance (IGT) to those with FPG of 6.1-6.9 mmol/l. A community-based cross-sectional survey in Chinese adults (20-74 years) was conducted during April-July in 2002. Participants without a prior history of diabetes underwent a standardized 2-h 75 g oral glucose tolerance test. Positive likelihood ratios were calculated to estimate the odds of having diabetes or IGT for subjects with different FPG levels. Among 1856 participants, prevalence of IFG increased from 12.4 to 28.2% with the cut-off value of FPG lowered from 6.1 to 5.6 mmol/l. Individuals with FPG of 6.1-6.9 mmol/l were more obese and insulin resistant than those with FPG of 5.6-6.0 mmol/l. The positive likelihood ratio for diabetes and IGT were 1.83 (1.28-2.61) and 2.60 (1.96-3.44) in subjects with FPG of 6.1-6.9 mmol/l, and 0.54 (0.30-0.95) and 1.47 (1.11-1.95) for those with FPG of 5.6-6.0 mmol/l, respectively. In conclusion, the likelihood of diabetes and IGT was lower in subjects with FPG of 5.6-6.0 mmol/l than in those with FPG of 6.1-6.9 mmol/l. The clinical and social implication of labelling more individuals with impaired fasting glucose needs to be further studied.

Authors+Show Affiliations

Department of Public Health, University of Helsinki, Helsinki, Finland. aambaam@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17825938

Citation

Gao, Weiguo, et al. "The Likelihood of Diabetes Based On the Proposed Definitions for Impaired Fasting Glucose." Diabetes Research and Clinical Practice, vol. 79, no. 1, 2008, pp. 151-5.
Gao W, Dong Y, Nan H, et al. The likelihood of diabetes based on the proposed definitions for impaired fasting glucose. Diabetes Res Clin Pract. 2008;79(1):151-5.
Gao, W., Dong, Y., Nan, H., Tuomilehto, J., & Qiao, Q. (2008). The likelihood of diabetes based on the proposed definitions for impaired fasting glucose. Diabetes Research and Clinical Practice, 79(1), 151-5.
Gao W, et al. The Likelihood of Diabetes Based On the Proposed Definitions for Impaired Fasting Glucose. Diabetes Res Clin Pract. 2008;79(1):151-5. PubMed PMID: 17825938.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The likelihood of diabetes based on the proposed definitions for impaired fasting glucose. AU - Gao,Weiguo, AU - Dong,Yanhu, AU - Nan,Hairong, AU - Tuomilehto,Jaakko, AU - Qiao,Qing, Y1 - 2007/09/07/ PY - 2006/06/26/received PY - 2007/07/25/accepted PY - 2007/9/11/pubmed PY - 2008/3/8/medline PY - 2007/9/11/entrez SP - 151 EP - 5 JF - Diabetes research and clinical practice JO - Diabetes Res Clin Pract VL - 79 IS - 1 N2 - The current study aimed to evaluate whether individuals with fasting plasma glucose (FPG) of 5.6-6.0 mmol/l has a similar risk profiles for diabetes or impaired glucose tolerance (IGT) to those with FPG of 6.1-6.9 mmol/l. A community-based cross-sectional survey in Chinese adults (20-74 years) was conducted during April-July in 2002. Participants without a prior history of diabetes underwent a standardized 2-h 75 g oral glucose tolerance test. Positive likelihood ratios were calculated to estimate the odds of having diabetes or IGT for subjects with different FPG levels. Among 1856 participants, prevalence of IFG increased from 12.4 to 28.2% with the cut-off value of FPG lowered from 6.1 to 5.6 mmol/l. Individuals with FPG of 6.1-6.9 mmol/l were more obese and insulin resistant than those with FPG of 5.6-6.0 mmol/l. The positive likelihood ratio for diabetes and IGT were 1.83 (1.28-2.61) and 2.60 (1.96-3.44) in subjects with FPG of 6.1-6.9 mmol/l, and 0.54 (0.30-0.95) and 1.47 (1.11-1.95) for those with FPG of 5.6-6.0 mmol/l, respectively. In conclusion, the likelihood of diabetes and IGT was lower in subjects with FPG of 5.6-6.0 mmol/l than in those with FPG of 6.1-6.9 mmol/l. The clinical and social implication of labelling more individuals with impaired fasting glucose needs to be further studied. SN - 1872-8227 UR - https://www.unboundmedicine.com/medline/citation/17825938/The_likelihood_of_diabetes_based_on_the_proposed_definitions_for_impaired_fasting_glucose_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-8227(07)00350-6 DB - PRIME DP - Unbound Medicine ER -