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Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs.
Bioresour Technol. 2008 Jun; 99(9):3908-13.BT

Abstract

In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be L-bornyl acetate (15.89%), caryophyllene oxide (12.98%), gamma-eudesmol (8.03%), beta-caryophyllene (6.60%), T-cadinol (5.49%), delta-cadinene (4.79%), trans-beta-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, L-borneol, L-bornyl acetate, eugenol, beta-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products.

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Publisher Full Text

Authors+Show Affiliations

Tung YT
School of Forestry and Resource Conservation, National Taiwan University, Taipei 106, Taiwan.
Chua MT
No affiliation info available
Wang SY
No affiliation info available
Chang ST
No affiliation info available

MeSH

AcroleinAnimalsAnti-Inflammatory AgentsCell DeathCell LineCinnamomumCurcuminDinoprostoneHumansLipopolysaccharidesMiceNitric OxideOils, Volatile

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

17826984

Clinical Trial Links

The Effect of Cinnamon on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome; a Pilot Study

Citation

Tung, Yu-Tang, et al. "Anti-inflammation Activities of Essential Oil and Its Constituents From Indigenous Cinnamon (Cinnamomum Osmophloeum) Twigs." Bioresource Technology, vol. 99, no. 9, 2008, pp. 3908-13.
Tung YT, Chua MT, Wang SY, et al. Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresour Technol. 2008;99(9):3908-13.
Tung, Y. T., Chua, M. T., Wang, S. Y., & Chang, S. T. (2008). Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. Bioresource Technology, 99(9), 3908-13.
Tung YT, et al. Anti-inflammation Activities of Essential Oil and Its Constituents From Indigenous Cinnamon (Cinnamomum Osmophloeum) Twigs. Bioresour Technol. 2008;99(9):3908-13. PubMed PMID: 17826984.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammation activities of essential oil and its constituents from indigenous cinnamon (Cinnamomum osmophloeum) twigs. AU - Tung,Yu-Tang, AU - Chua,Meng-Thong, AU - Wang,Sheng-Yang, AU - Chang,Shang-Tzen, Y1 - 2007/09/10/ PY - 2007/05/29/received PY - 2007/07/27/revised PY - 2007/07/27/accepted PY - 2007/9/11/pubmed PY - 2008/5/22/medline PY - 2007/9/11/entrez SP - 3908 EP - 13 JF - Bioresource technology JO - Bioresour Technol VL - 99 IS - 9 N2 - In this study, chemical compositions of hydrodistilled essential oil and anti-inflammatory activities from the twigs of Cinnamomum osmophloeum Kaneh. were investigated for the first time. The chemical constituents of the twig essential oil were further analyzed by GC-MS and they were found to be L-bornyl acetate (15.89%), caryophyllene oxide (12.98%), gamma-eudesmol (8.03%), beta-caryophyllene (6.60%), T-cadinol (5.49%), delta-cadinene (4.79%), trans-beta-elemenone (4.25%), cadalene (4.19%), and trans-cinnamaldehyde (4.07%). The effects of essential oil on nitric oxide (NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages were also examined. Results of nitric oxide tests indicated that twig essential oil and its major constituents such as trans-cinnamaldehyde, caryophyllene oxide, L-borneol, L-bornyl acetate, eugenol, beta-caryophyllene, E-nerolidol, and cinnamyl acetate have excellent activities. These findings demonstrated that essential oil of C. osmophloeum twigs have excellent anti-inflammatory activities and thus have great potential to be used as a source for natural health products. SN - 0960-8524 UR - https://www.unboundmedicine.com/medline/citation/17826984/Anti_inflammation_activities_of_essential_oil_and_its_constituents_from_indigenous_cinnamon__Cinnamomum_osmophloeum__twigs_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0960-8524(07)00609-8 DB - PRIME DP - Unbound Medicine ER -