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Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues.
Dig Dis. 2007; 25(3):241-4.DD

Abstract

Several reports have described post-infectious irritable bowel syndrome (Pi-IBS), while many animal and human studies have shown the presence of increased infiltration of inflammatory cells and hyperplasia of enterochromaffin cells in the intestinal mucosa after acute gastroenteritis. The potential value of probiotic bacteria in restoring normal gut function has been demonstrated by animal models of Pi-IBS. In humans, Pi-IBS can be prevented utilizing probiotics to reduce the duration of acute gastroenteritis, despite the variable efficacy shown in randomized control trials evaluating unspecified IBS. Here, advances in the pathophysiology supporting the post-infectious hypothesis are considered. In addition, the current role of probiotics in the management of Pi-IBS is discussed.

Authors+Show Affiliations

Gastroenterological Unit, Department of Clinical and Experimental Medicine, University of Naples Federico II, Naples, Italy. rcuomo@unina.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

17827948

Citation

Cuomo, Rosario, et al. "Almost All Irritable Bowel Syndromes Are Post-infectious and Respond to Probiotics: Consensus Issues." Digestive Diseases (Basel, Switzerland), vol. 25, no. 3, 2007, pp. 241-4.
Cuomo R, Savarese MF, Gargano R. Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues. Dig Dis. 2007;25(3):241-4.
Cuomo, R., Savarese, M. F., & Gargano, R. (2007). Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues. Digestive Diseases (Basel, Switzerland), 25(3), 241-4.
Cuomo R, Savarese MF, Gargano R. Almost All Irritable Bowel Syndromes Are Post-infectious and Respond to Probiotics: Consensus Issues. Dig Dis. 2007;25(3):241-4. PubMed PMID: 17827948.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Almost all irritable bowel syndromes are post-infectious and respond to probiotics: consensus issues. AU - Cuomo,Rosario, AU - Savarese,Maria Flavia, AU - Gargano,Rosalba, PY - 2007/9/11/pubmed PY - 2007/10/25/medline PY - 2007/9/11/entrez SP - 241 EP - 4 JF - Digestive diseases (Basel, Switzerland) JO - Dig Dis VL - 25 IS - 3 N2 - Several reports have described post-infectious irritable bowel syndrome (Pi-IBS), while many animal and human studies have shown the presence of increased infiltration of inflammatory cells and hyperplasia of enterochromaffin cells in the intestinal mucosa after acute gastroenteritis. The potential value of probiotic bacteria in restoring normal gut function has been demonstrated by animal models of Pi-IBS. In humans, Pi-IBS can be prevented utilizing probiotics to reduce the duration of acute gastroenteritis, despite the variable efficacy shown in randomized control trials evaluating unspecified IBS. Here, advances in the pathophysiology supporting the post-infectious hypothesis are considered. In addition, the current role of probiotics in the management of Pi-IBS is discussed. SN - 1421-9875 UR - https://www.unboundmedicine.com/medline/citation/17827948/Almost_all_irritable_bowel_syndromes_are_post_infectious_and_respond_to_probiotics:_consensus_issues_ L2 - https://www.karger.com?DOI=10.1159/000103893 DB - PRIME DP - Unbound Medicine ER -