Tags

Type your tag names separated by a space and hit enter

Liquid-core waveguide in CE.
Electrophoresis. 2007 Oct; 28(19):3414-9.E

Abstract

Liquid-core waveguide (LCW) brings about several advantages in CE. This review discusses some aspects of fundamental and practical importance involved in this method. Sensitivity in absorption and fluorescence detection is in general improved by more than one order of magnitude over usual crossbeam detection arrangements; the improvements come from the long light path in absorption detection and low light scattering in fluorescence detection. Versatile instrumental arrangements are another advantage of LCW in CE, leading to several detection schemes, some of which provide information that is not gained by usual capillary-end crossbeam detection, e.g. whole-capillary imaging, simultaneous monitoring of multicapillary separation, and kinetic evaluation. The high potential and perspectives of LCW in CE are discussed based on the state-of-the-art developments.

Authors+Show Affiliations

Okada T
Department of Chemistry, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8551, Japan. tokada@chem.titech.ac.jp

MeSH

Electrophoresis, CapillaryFiber Optic TechnologyIsoelectric FocusingMicrofluidic Analytical TechniquesMiniaturizationReproducibility of ResultsScattering, RadiationSensitivity and SpecificitySpectrometry, Fluorescence

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

17828798

Citation

Okada, Tetsuo. "Liquid-core Waveguide in CE." Electrophoresis, vol. 28, no. 19, 2007, pp. 3414-9.
Okada T. Liquid-core waveguide in CE. Electrophoresis. 2007;28(19):3414-9.
Okada, T. (2007). Liquid-core waveguide in CE. Electrophoresis, 28(19), 3414-9.
Okada T. Liquid-core Waveguide in CE. Electrophoresis. 2007;28(19):3414-9. PubMed PMID: 17828798.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Liquid-core waveguide in CE. A1 - Okada,Tetsuo, PY - 2007/9/11/pubmed PY - 2008/2/7/medline PY - 2007/9/11/entrez SP - 3414 EP - 9 JF - Electrophoresis JO - Electrophoresis VL - 28 IS - 19 N2 - Liquid-core waveguide (LCW) brings about several advantages in CE. This review discusses some aspects of fundamental and practical importance involved in this method. Sensitivity in absorption and fluorescence detection is in general improved by more than one order of magnitude over usual crossbeam detection arrangements; the improvements come from the long light path in absorption detection and low light scattering in fluorescence detection. Versatile instrumental arrangements are another advantage of LCW in CE, leading to several detection schemes, some of which provide information that is not gained by usual capillary-end crossbeam detection, e.g. whole-capillary imaging, simultaneous monitoring of multicapillary separation, and kinetic evaluation. The high potential and perspectives of LCW in CE are discussed based on the state-of-the-art developments. SN - 0173-0835 UR - https://www.unboundmedicine.com/medline/citation/17828798/Liquid_core_waveguide_in_CE_ DB - PRIME DP - Unbound Medicine ER -