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Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytes.
J Reprod Med. 2007 Jul; 52(7):585-90.JR

Abstract

OBJECTIVE

To evaluate obstetric complications in women conceiving with donated oocytes as compared to controls of advanced maternal age.

STUDY DESIGN

We compared the obstetric outcomes of a cohort of 69 women who conceived through oocyte donation to all women over 38 years old (n = 681) who delivered at the same hospital in the same period. We first compared obstetric complications and outcomes in the entire cohort. Additional comparisons were made while controlling for multiple covariates: maternal and fetal complications, mode of delivery, estimated gestational age and infant weight at delivery.

RESULTS

Women who conceived with donor oocytes were older than controls. In the cohort, oocyte recipients were at increased risk for several obstetric complications. However, when controlling for age and multiple gestations, only preterm labor, preeclampsia and protracted labor were increased in oocyte recipients.

CONCLUSION

Women who conceive with donor oocytes might be at increased risk of complications during pregnancy. When age and multiple gestations are accounted for, these patients remain at risk for preterm labor, preeclampsia and protracted labor requiring cesarean delivery.

Authors+Show Affiliations

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

17847755

Citation

Henne, Melinda B., et al. "Comparison of Obstetric Outcomes in Recipients of Donor Oocytes Vs. Women of Advanced Maternal Age With Autologous Oocytes." The Journal of Reproductive Medicine, vol. 52, no. 7, 2007, pp. 585-90.
Henne MB, Zhang M, Paroski S, et al. Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytes. J Reprod Med. 2007;52(7):585-90.
Henne, M. B., Zhang, M., Paroski, S., Kelshikar, B., & Westphal, L. M. (2007). Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytes. The Journal of Reproductive Medicine, 52(7), 585-90.
Henne MB, et al. Comparison of Obstetric Outcomes in Recipients of Donor Oocytes Vs. Women of Advanced Maternal Age With Autologous Oocytes. J Reprod Med. 2007;52(7):585-90. PubMed PMID: 17847755.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytes. AU - Henne,Melinda B, AU - Zhang,Mallory, AU - Paroski,Sylvie, AU - Kelshikar,Bhagyashree, AU - Westphal,Lynn M, PY - 2007/9/13/pubmed PY - 2007/10/17/medline PY - 2007/9/13/entrez SP - 585 EP - 90 JF - The Journal of reproductive medicine JO - J Reprod Med VL - 52 IS - 7 N2 - OBJECTIVE: To evaluate obstetric complications in women conceiving with donated oocytes as compared to controls of advanced maternal age. STUDY DESIGN: We compared the obstetric outcomes of a cohort of 69 women who conceived through oocyte donation to all women over 38 years old (n = 681) who delivered at the same hospital in the same period. We first compared obstetric complications and outcomes in the entire cohort. Additional comparisons were made while controlling for multiple covariates: maternal and fetal complications, mode of delivery, estimated gestational age and infant weight at delivery. RESULTS: Women who conceived with donor oocytes were older than controls. In the cohort, oocyte recipients were at increased risk for several obstetric complications. However, when controlling for age and multiple gestations, only preterm labor, preeclampsia and protracted labor were increased in oocyte recipients. CONCLUSION: Women who conceive with donor oocytes might be at increased risk of complications during pregnancy. When age and multiple gestations are accounted for, these patients remain at risk for preterm labor, preeclampsia and protracted labor requiring cesarean delivery. SN - 0024-7758 UR - https://www.unboundmedicine.com/medline/citation/17847755/Comparison_of_obstetric_outcomes_in_recipients_of_donor_oocytes_vs__women_of_advanced_maternal_age_with_autologous_oocytes_ L2 - https://medlineplus.gov/organdonation.html DB - PRIME DP - Unbound Medicine ER -